Ch. 1 Intro to Clinical Pharmacology
Pharmacology The biomedical study of the interaction of chemical substances with living systems,
including cells, tissues, and organisms.
FDA A governmental agency is responsible for the approval of drugs, food, and
cosmetics
Drugs Substances or chemical agents that affect biological or living systems, but do not
create new physiological responses
biologics Agents that are naturally produced in the animal or human body
EX: Vaccines, Blood, and blood components
Pharmakonetics The way the body affects the drug (absorption, distribution, metabolism, and
excretion)
Pharmacodynamics The action a drug has on a specific target
Posology Study of the dosages of medicines and drugs
Therapeutics Branch of medicine that deals with the treatment of disease
Pharmacotherapeutics The study of how drugs may be used in the treatment of disease
Pharmacogenetics The convergence of psychology and genetics deals with genetic factors that
influence an organism's response to a drug.
Toxicology The scientific study of poisons, chemical pollutants, and the undesirable effects of
cells, tissues, and organisms
What are Phase 1 trials? The first time a drug is administered into a human being.
Purpose of Phase 1 trial To determine the proper and safe dose of the drug.
Phase 2 trials After safety has been documented, human subjects with the specific disease for the
drug are given the drug and monitored
Phase 3 trial Review of a new drug application
, Ch. 1 Intro to Clinical Pharmacology
Phase 4 trial Final stage of drug approval that monitors the actual use of the drug in dental/
medical practice
Class I recall Reasonable chance that exposure to the product with cause adverse health effects
Class II recall when the use of a product may cause temporary or reversible health problems
Class III recall use of or exposure to a product is not likely to cause health problems
Chemical Name of drug long and complicated; refers to the makeup of the drug
Chemical Name of acetaminophen N-(hydroxyphenyl) acetamide
Generic Name official preferred name, far less complicated and easier to pronounce
EX: acetaminophen
Brand Name A drug that is registered to a trademark that belongs to a specific drug manufacturer
EX: Tylenol
prescription order to dispense a specific drug for the patient
Parts of a prescription Heading
Body
Closing
Heading Prescriber and pt information, including prescribers name, and address
Body Contains the symbol RX, drug generic or brand) strength and quantity to be
dispensed
closing contains the prescriber's signature, DEA number, refill information, check off box,
and expiration date
Pharmacology The biomedical study of the interaction of chemical substances with living systems,
including cells, tissues, and organisms.
FDA A governmental agency is responsible for the approval of drugs, food, and
cosmetics
Drugs Substances or chemical agents that affect biological or living systems, but do not
create new physiological responses
biologics Agents that are naturally produced in the animal or human body
EX: Vaccines, Blood, and blood components
Pharmakonetics The way the body affects the drug (absorption, distribution, metabolism, and
excretion)
Pharmacodynamics The action a drug has on a specific target
Posology Study of the dosages of medicines and drugs
Therapeutics Branch of medicine that deals with the treatment of disease
Pharmacotherapeutics The study of how drugs may be used in the treatment of disease
Pharmacogenetics The convergence of psychology and genetics deals with genetic factors that
influence an organism's response to a drug.
Toxicology The scientific study of poisons, chemical pollutants, and the undesirable effects of
cells, tissues, and organisms
What are Phase 1 trials? The first time a drug is administered into a human being.
Purpose of Phase 1 trial To determine the proper and safe dose of the drug.
Phase 2 trials After safety has been documented, human subjects with the specific disease for the
drug are given the drug and monitored
Phase 3 trial Review of a new drug application
, Ch. 1 Intro to Clinical Pharmacology
Phase 4 trial Final stage of drug approval that monitors the actual use of the drug in dental/
medical practice
Class I recall Reasonable chance that exposure to the product with cause adverse health effects
Class II recall when the use of a product may cause temporary or reversible health problems
Class III recall use of or exposure to a product is not likely to cause health problems
Chemical Name of drug long and complicated; refers to the makeup of the drug
Chemical Name of acetaminophen N-(hydroxyphenyl) acetamide
Generic Name official preferred name, far less complicated and easier to pronounce
EX: acetaminophen
Brand Name A drug that is registered to a trademark that belongs to a specific drug manufacturer
EX: Tylenol
prescription order to dispense a specific drug for the patient
Parts of a prescription Heading
Body
Closing
Heading Prescriber and pt information, including prescribers name, and address
Body Contains the symbol RX, drug generic or brand) strength and quantity to be
dispensed
closing contains the prescriber's signature, DEA number, refill information, check off box,
and expiration date
