Mental Health Assessment & Differential
Diagnosis Practice Exam 2026/2027 | Practice
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Question 1
A 28-year-old client reports six months of excessive worry about
finances, work performance, family health, and everyday
responsibilities. The client describes the worry as difficult to
control and reports muscle tension, irritability, fatigue, and poor
sleep. Which diagnosis should the PMHNP consider most
strongly?
A. Panic disorder
B. Generalized anxiety disorder
C. Adjustment disorder
D. Obsessive-compulsive disorder
Correct Answer: B. Generalized anxiety disorder
,Rationale: Generalized anxiety disorder is characterized by
excessive anxiety and worry about multiple areas of life that is
difficult to control and occurs more days than not for at least six
months. Associated symptoms commonly include restlessness,
fatigue, difficulty concentrating, irritability, muscle tension, and
sleep disturbance. Panic disorder instead centers on recurrent
unexpected panic attacks and concern about additional attacks,
while obsessive-compulsive disorder involves obsessions and/or
compulsions. Adjustment disorder requires symptoms occurring
in response to an identifiable stressor and does not best explain
persistent, broad-based worry lasting six months.
Question 2
A client presents with new-onset hallucinations and paranoid
behavior. Which assessment is most important before
concluding that the client has a primary psychotic disorder?
A. Determine the client's preferred coping style
B. Assess for medical, substance-related, and medication-
related causes
C. Determine whether the client has a history of childhood
trauma
D. Ask whether the client prefers individual or group therapy
Correct Answer: B. Assess for medical, substance-related, and
medication-related causes
,Rationale: New-onset psychosis requires careful evaluation for
secondary causes before assigning a primary psychiatric
diagnosis. Medical disorders, neurologic conditions,
intoxication, withdrawal, and medications can produce
psychotic symptoms. Establishing whether symptoms have a
medical or substance-related explanation is a fundamental
component of differential diagnosis and prevents potentially
reversible conditions from being overlooked. Psychosocial
history remains important, but it does not replace evaluation for
potentially urgent medical or substance-related causes.
Question 3
A client reports hearing a voice that speaks directly to the client
when no one is present. How should this symptom be
documented?
A. Visual hallucination
B. Auditory hallucination
C. Somatic delusion
D. Illusion
Correct Answer: B. Auditory hallucination
Rationale: An auditory hallucination is a perception of sound or
a voice without an external auditory stimulus. A visual
hallucination involves seeing something that is not present. A
, delusion is a fixed false belief rather than a perceptual
experience. An illusion occurs when an actual external stimulus
is misinterpreted. Accurate identification of the type of
perceptual disturbance helps establish an appropriate
differential diagnosis.
Question 4
A client reports a persistent belief that coworkers are secretly
communicating about the client through ordinary television
advertisements. There is no evidence supporting the belief.
Which symptom is most consistent with this presentation?
A. Delusion
B. Obsession
C. Compulsion
D. Depersonalization
Correct Answer: A. Delusion
Rationale: A delusion is a fixed belief that is not consistent with
available evidence and is not better explained by cultural or
religious beliefs. The client's interpretation of ordinary
advertisements as secret communications represents a false,
fixed belief. An obsession is an intrusive, unwanted thought or
urge, whereas a compulsion is a repetitive behavior or mental
act performed in response to an obsession. Depersonalization