NUR 2407 PHARMACOLOGY QUIZ 3
COMPREHENSIVE ASSESSMENT
1. A patient is prescribed Omeprazole (Prilosec) for GERD. Which statement by the patient
indicates a need for further teaching regarding the mechanism of Proton Pump Inhibitors
(PPIs)?
A. This medication blocks the final step of acid production.
B. This drug irreversibly inhibits the H+/K+ ATPase enzyme system.
C. I should take this medication 30 minutes after my largest meal.
D. I may need to be monitored for bone density loss if I take this long-term.
Answer: C
Conceptual Explanation: PPIs like Omeprazole should be taken 30 to 60 minutes BEFORE
meals, usually in the morning, to provide maximum inhibition of acid secretion stimulated
by food. Taking it after a meal is incorrect.
2. A nurse is preparing to administer Lispro (Humalog) insulin to a patient. At what time
should the nurse ensure the patient’s meal tray is available?
A. Immediately following the morning walk
,B. Exactly 45 minutes after administration
C. One hour after administration
D. Within 15 minutes of administration
Answer: D
Conceptual Explanation: Lispro is a rapid-acting insulin with an onset of 15 minutes. To
prevent hypoglycemia, the patient must eat within 15 minutes of the injection.
3. The nurse is reviewing the laboratory results of a patient taking Levothyroxine (Synthroid).
Which result would indicate the dosage is too high?
A. Elevated Thyroid Stimulating Hormone (TSH)
B. Low Thyroid Stimulating Hormone (TSH)
C. Decreased T3 and T4 levels
D. Normal Serum Glucose levels
Answer: B
Conceptual Explanation: In primary hypothyroidism, TSH is high because the body is
trying to stimulate the thyroid. If the Levothyroxine dose is too high (excessive), TSH will
drop below normal due to the negative feedback loop.
4. A patient with Type 2 Diabetes is scheduled for a CT scan with intravenous contrast dye.
Which medication must be held for 48 hours after the procedure?
A. Glipizide
, B. Pioglitazone
C. Metformin
D. Sitagliptin
Answer: C
Conceptual Explanation: Metformin must be held prior to and for 48 hours after
procedures involving iodine-based contrast media to prevent the risk of lactic acidosis if
renal failure occurs.
5. Which of the following is the most appropriate instruction for a patient prescribed
Sucralfate (Carafate) for a duodenal ulcer?
A. Take the medication with a high-fat meal to improve absorption.
B. Limit fluid intake to 500 mL per day while on this medication.
C. Crush the tablet and mix it with applesauce for better effect.
D. Take the medication on an empty stomach at least 1 hour before meals.
Answer: D
Conceptual Explanation: Sucralfate works by creating a protective barrier over the ulcer.
It requires an acidic environment and must be taken on an empty stomach (1 hour before
meals and at bedtime) to coat the ulcer before food arrives.
COMPREHENSIVE ASSESSMENT
1. A patient is prescribed Omeprazole (Prilosec) for GERD. Which statement by the patient
indicates a need for further teaching regarding the mechanism of Proton Pump Inhibitors
(PPIs)?
A. This medication blocks the final step of acid production.
B. This drug irreversibly inhibits the H+/K+ ATPase enzyme system.
C. I should take this medication 30 minutes after my largest meal.
D. I may need to be monitored for bone density loss if I take this long-term.
Answer: C
Conceptual Explanation: PPIs like Omeprazole should be taken 30 to 60 minutes BEFORE
meals, usually in the morning, to provide maximum inhibition of acid secretion stimulated
by food. Taking it after a meal is incorrect.
2. A nurse is preparing to administer Lispro (Humalog) insulin to a patient. At what time
should the nurse ensure the patient’s meal tray is available?
A. Immediately following the morning walk
,B. Exactly 45 minutes after administration
C. One hour after administration
D. Within 15 minutes of administration
Answer: D
Conceptual Explanation: Lispro is a rapid-acting insulin with an onset of 15 minutes. To
prevent hypoglycemia, the patient must eat within 15 minutes of the injection.
3. The nurse is reviewing the laboratory results of a patient taking Levothyroxine (Synthroid).
Which result would indicate the dosage is too high?
A. Elevated Thyroid Stimulating Hormone (TSH)
B. Low Thyroid Stimulating Hormone (TSH)
C. Decreased T3 and T4 levels
D. Normal Serum Glucose levels
Answer: B
Conceptual Explanation: In primary hypothyroidism, TSH is high because the body is
trying to stimulate the thyroid. If the Levothyroxine dose is too high (excessive), TSH will
drop below normal due to the negative feedback loop.
4. A patient with Type 2 Diabetes is scheduled for a CT scan with intravenous contrast dye.
Which medication must be held for 48 hours after the procedure?
A. Glipizide
, B. Pioglitazone
C. Metformin
D. Sitagliptin
Answer: C
Conceptual Explanation: Metformin must be held prior to and for 48 hours after
procedures involving iodine-based contrast media to prevent the risk of lactic acidosis if
renal failure occurs.
5. Which of the following is the most appropriate instruction for a patient prescribed
Sucralfate (Carafate) for a duodenal ulcer?
A. Take the medication with a high-fat meal to improve absorption.
B. Limit fluid intake to 500 mL per day while on this medication.
C. Crush the tablet and mix it with applesauce for better effect.
D. Take the medication on an empty stomach at least 1 hour before meals.
Answer: D
Conceptual Explanation: Sucralfate works by creating a protective barrier over the ulcer.
It requires an acidic environment and must be taken on an empty stomach (1 hour before
meals and at bedtime) to coat the ulcer before food arrives.
