NUR 641E Final Actual Questions and Correct Answers
Q1
Pharmacokinetics involves
Answer: a: Absorption: absorption from the administration site either directly or indirectly into
theblood/plasma.b: Distribution: reversibly or irreversibly move from the bloodstream into the
interstitial andintracellular fluid.c: Metabolism: biotransformed via hepatic metabolism or by other
tissues.d: Elimination: the drug and its metabolites are eliminated from the body
Q2
The route of administration with the highest bioavailability is
Answer: Intravenous, putting an entire dose into a patient's vein and bypassing absorption
Q3
Intravenous route avoids
Answer: First-pass metabolism in the liver
Q4
Rectal administration has
Answer: variable and erratic absorption
Q5
Steady State (SS) is usually reached within
Answer: 4-5 half-lives of a drug
Q6
First-order (linear) pharmacokinetics means
Answer: The metabolism is directly proportional to the free concentration of the drug
Q7
Zero-order (nonlinear)pharmacokinetics means
Answer: A drug is metabolized at a constant rate per unit time
Q1
Pharmacokinetics involves
Answer: a: Absorption: absorption from the administration site either directly or indirectly into
theblood/plasma.b: Distribution: reversibly or irreversibly move from the bloodstream into the
interstitial andintracellular fluid.c: Metabolism: biotransformed via hepatic metabolism or by other
tissues.d: Elimination: the drug and its metabolites are eliminated from the body
Q2
The route of administration with the highest bioavailability is
Answer: Intravenous, putting an entire dose into a patient's vein and bypassing absorption
Q3
Intravenous route avoids
Answer: First-pass metabolism in the liver
Q4
Rectal administration has
Answer: variable and erratic absorption
Q5
Steady State (SS) is usually reached within
Answer: 4-5 half-lives of a drug
Q6
First-order (linear) pharmacokinetics means
Answer: The metabolism is directly proportional to the free concentration of the drug
Q7
Zero-order (nonlinear)pharmacokinetics means
Answer: A drug is metabolized at a constant rate per unit time