2026 NEWEST EXAM PREP COMPLETE QUESTIONS AND CORRECT
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SECTION 1: ANATOMY & PHYSIOLOGY OF THE RESPIRATORY SYSTEM
(Questions 1-25)
QUESTION 1
What is the primary muscle of inspiration?
A) Internal intercostals
B) Diaphragm
C) External intercostals
D) Abdominal muscles
ANSWER: B
EXPLANATION: The diaphragm is the primary muscle of inspiration. When it
contracts, it flattens and moves downward, increasing the vertical diameter
of the thoracic cavity. This creates negative pressure that draws air into
the lungs. The external intercostals also assist with inspiration by elevating
the ribs. The internal intercostals and abdominal muscles are muscles of
expiration.
QUESTION 2
The anatomical dead space is composed of which of the following?
A) Alveoli and respiratory bronchioles
B) Trachea, bronchi, and terminal bronchioles
C) Respiratory bronchioles and alveolar ducts
D) All airways from the nose to the alveoli
ANSWER: B
EXPLANATION: Anatomical dead space is the volume of air in the conducting
airways (trachea, bronchi, terminal bronchioles) that does not participate in
gas exchange. It is approximately 1 mL per pound of ideal body weight, or about
1
,150 mL in an average adult. Alveoli are part of the respiratory zone where gas
exchange occurs. Physiological dead space includes anatomical dead space plus
alveolar dead space (ventilated but not perfused alveoli).
QUESTION 3
What is the normal tidal volume for a healthy adult?
A) 2-3 mL/kg
B) 5-7 mL/kg
C) 8-10 mL/kg
D) 10-15 mL/kg
ANSWER: B
EXPLANATION: Normal tidal volume (VT) in a healthy adult is approximately
5-7 mL/kg of ideal body weight, typically 400-600 mL. This is the volume
of air inspired and expired with each normal breath. Tidal volume can be
measured with a spirometer. Alveolar ventilation is calculated as:
(VT - Dead space) × Respiratory rate.
QUESTION 4
Which structure is the primary site of gas exchange in the lungs?
A) Terminal bronchioles
B) Respiratory bronchioles
C) Alveolar ducts
D) Alveoli
ANSWER: D
EXPLANATION: The alveoli are the primary site of gas exchange in the lungs.
They are small, thin-walled sacs surrounded by pulmonary capillaries.
Oxygen diffuses from the alveoli into the blood, and carbon dioxide diffuses
from the blood into the alveoli. The alveolar-capillary membrane is very thin
(0.2-0.5 microns) to facilitate efficient gas exchange.
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,QUESTION 5
What is the normal minute ventilation for a healthy adult?
A) 2-4 L/min
B) 5-8 L/min
C) 10-12 L/min
D) 15-20 L/min
ANSWER: B
EXPLANATION: Normal minute ventilation is approximately 5-8 L/min. It is
calculated as tidal volume multiplied by respiratory rate. For example, if
tidal volume is 500 mL and respiratory rate is 12 breaths/min, minute
ventilation is 6 L/min. Alveolar ventilation is the volume of air that reaches
the alveoli per minute and is calculated as (VT - VD) × RR.
QUESTION 6
What is the function of type II pneumocytes in the alveoli?
A) Gas exchange
B) Production of surfactant
C) Phagocytosis of debris
D) Immune defense
ANSWER: B
EXPLANATION: Type II pneumocytes (type II alveolar cells) produce surfactant,
a phospholipid-protein substance that reduces surface tension in the alveoli.
Surfactant prevents alveolar collapse during expiration and keeps the alveoli
stable. Type I pneumocytes are the cells responsible for gas exchange.
Alveolar macrophages are responsible for phagocytosis.
QUESTION 7
Which of the following is NOT a function of the upper airway?
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, A) Warming inspired air
B) Humidifying inspired air
C) Gas exchange
D) Filtering inspired air
ANSWER: C
EXPLANATION: Gas exchange is a function of the lower airways (alveoli), not
the upper airway. The upper airway warms, humidifies, and filters inspired
air. The nose, pharynx, and larynx provide these functions. The upper airway
also houses the vocal cords for speech and protects the lower airway from
aspiration.
QUESTION 8
What is the normal resting respiratory rate for a healthy adult?
A) 8-10 breaths/min
B) 12-20 breaths/min
C) 20-28 breaths/min
D) 28-36 breaths/min
ANSWER: B
EXPLANATION: The normal resting respiratory rate for a healthy adult is
12-20 breaths/min. Tachypnea is a respiratory rate >20 breaths/min.
Bradypnea is a respiratory rate <12 breaths/min. Infants and children have
higher normal respiratory rates. The respiratory rate is controlled by the
respiratory centers in the brainstem (medulla oblongata and pons).
QUESTION 9
What is the functional residual capacity (FRC)?
A) The volume of air remaining in the lungs after a normal expiration
B) The volume of air remaining in the lungs after a maximal expiration
C) The volume of air inhaled during a normal breath
D) The maximum volume of air that can be exhaled after a maximal inspiration
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