NURS 365 PHARMACOLOGY EXAM 1 UPDATED ACTUAL
QUESTIONS AND CORRECT ANSWERS
Question:
1. Select the most important property of an ideal drug.
A)Safety
B)Effectiveness
C)Predictability
D)Selectivity
Answer:
B
Question:
2. A drug that elicits only those responses for which it is given is considered to be:
A)predictable
B)safe
C)effective
D)selective
Answer:
D
Question:
3. When a disease process triggers increased metabolism of a drug, the disease has altered the drug's:
A)selectivity.
B)pharmacodynamics.
C)pharmacokinetics.
D)pharmacotherapeutics.
Answer:
C
Question:
4. During which step of the nursing process will a nurse develop a teaching program for a diabetic patient
who is designated to start insulin therapy?
A)Assessment
B)Planning
C)Analysis
D)Implementation
E)Evaluation
Answer:
B
,Question:
5. Which of the following is a component of the baseline data that the nurse collects prior to administering
an antihypertensive agent to any patient?
A)The patient's blood pressure prior to administration.
B)Drug storage information.
C)The route by which the drug was ordered to be administered.
D)The early signs that an adverse reaction is occurring.
Answer:
A
Question:
6. The nurse is reviewing drug literature about a medication that he is preparing to administer. The
literature mentions precautions. Which of the following is the best example of a patient in whom
precautions are warranted for administration of penicillin?
A)In a patient who is allergic to sulfa drugs, but has no history of reactions to penicillin.
B)In a patient who reports a remote history of a mild rash from penicillin taken 20 years ago.
C)In a patient who has never received penicillin or any related agents.
D)In a patient who has a history of anaphylaxis from penicillin
Answer:
B
Question:
7. Drug distribution is determined by:
A)blood flow out of the tissues
B)the density of capillary beds
C)the ability of the drug to exit the vascular system
D)the ability of the drug to exit cells
Answer:
C
Question:
8. A patient is receiving the drug warfarin, a drug with a strong attraction to albumin. While taking the
warfarin, the patient begins to take a second drug that also has a strong attraction to albumin. The nurse
would need to watch the patient for signs of:
A)decreased effects of the warfarin because the second drug may cause the warfarin to bind more strongly
to the albumin
B)toxic levels of warfarin because the second drug may displace the warfarin from the albumin
C)subtherapeutic levels of warfarin because the second drug may displace the warfarin from the albumin
D)increased effects of the warfarin because the second drug may cause the warfarin to bind more strongly
to the albumin
Answer:
B
,Question:
9. A patient has been taking a medication to prevent seizures. What is the best rationale for measuring
therapeutic drug levels?
A)There is a direct correlation between therapeutic and toxic levels for most drugs
B)Plasma drug levels are better indicators of drug efficacy than are clinical symptoms.
C)Drug levels that are within the therapeutic range cannot be associated with toxicity.
D)Drug levels below the therapeutic range can never be effective.
Answer:
A
Question:
10. Which of the following is a true statement in regard to pH-dependent ionization?
A)Bases will ionize in an alkaline medium.
B)Medications are not affected by the surrounding pH in body tissues.
C)Acids will ionize best in an acidic medium.
D)An acid is a proton donor, while a base is a proton acceptor.
Answer:
D
Question:
11. The binding of a drug to its receptor is _______ reversible.
A)rarely
B)never
C)usually
D)always
Answer:
C
Question:
12. The majority of drug metabolism is catalyzed by the cytochrome P450 group of liver enzymes. When
these enzymes are inhibited, a drug given simultaneously will:
A)have no effect in the body
B)create the potential for anaphylaxis
C)be inhibited, and levels in the body will drop
D)reach higher-than-intended levels in the body
Answer:
D
Question:
13. Most people who receive a neuromuscular blocker during surgery have a brief response lasting only a
few minutes. A person who has a very prolonged effect from the drug at a standard dosage is experiencing:
A)a physical dependence
B)an idiosyncratic effect
C)an anaphylactic reaction
D)an iatrogenic response
Answer:
B
, Question:
14. When determining whether an adverse drug reaction has occurred, the nurse should consider which
question?
A)Could the pathophysiologic events of the illness itself explain the effect?
B)Is the patient complaining about the frequency of drug dosing?
C)Has the drug produced this effect in another patient receiving the same agent at the same dose?
D)Did the patient notice that the drug caused a bad taste in the mouth?
Answer:
A
Question:
15. Select the accurate statement regarding gender differences in response to drugs.
A)Women are inefficient metabolizers of drugs, and will be more prone to side effects.
B)Men metabolize drugs more effectively, and are therefore more likely to experience the intended drug
effect.
C)Men and women may respond differently to drugs, but little is known about how and why.
D)Gender has no effect on drug kinetics or dynamics.
Answer:
C
Question:
16. A drug given by which of the following routes would be most likely to exhibit the first-pass effect?
A)subcutaneous
B)intravenous
C)oral
D)sublingual
Answer:
C
Question:
17. When discussing the concept of drug tolerance, the nurse should include the fact that
A)addiction is likely to develop if the drug is not tapered
B)this means that the patient will require more drug to achieve the same effect
C)the phenomenon only occurs with opioid medications
D)the patient requires a stable dose of medication until the drug is discontinued
Answer:
B
Question:
18. Which of the following drugs will cross the placenta most readily?
A)Highly polar drugs
B)Ionized drugs
C)Lipid-soluble drugs
D)Protein-bound drugs
Answer:
C
QUESTIONS AND CORRECT ANSWERS
Question:
1. Select the most important property of an ideal drug.
A)Safety
B)Effectiveness
C)Predictability
D)Selectivity
Answer:
B
Question:
2. A drug that elicits only those responses for which it is given is considered to be:
A)predictable
B)safe
C)effective
D)selective
Answer:
D
Question:
3. When a disease process triggers increased metabolism of a drug, the disease has altered the drug's:
A)selectivity.
B)pharmacodynamics.
C)pharmacokinetics.
D)pharmacotherapeutics.
Answer:
C
Question:
4. During which step of the nursing process will a nurse develop a teaching program for a diabetic patient
who is designated to start insulin therapy?
A)Assessment
B)Planning
C)Analysis
D)Implementation
E)Evaluation
Answer:
B
,Question:
5. Which of the following is a component of the baseline data that the nurse collects prior to administering
an antihypertensive agent to any patient?
A)The patient's blood pressure prior to administration.
B)Drug storage information.
C)The route by which the drug was ordered to be administered.
D)The early signs that an adverse reaction is occurring.
Answer:
A
Question:
6. The nurse is reviewing drug literature about a medication that he is preparing to administer. The
literature mentions precautions. Which of the following is the best example of a patient in whom
precautions are warranted for administration of penicillin?
A)In a patient who is allergic to sulfa drugs, but has no history of reactions to penicillin.
B)In a patient who reports a remote history of a mild rash from penicillin taken 20 years ago.
C)In a patient who has never received penicillin or any related agents.
D)In a patient who has a history of anaphylaxis from penicillin
Answer:
B
Question:
7. Drug distribution is determined by:
A)blood flow out of the tissues
B)the density of capillary beds
C)the ability of the drug to exit the vascular system
D)the ability of the drug to exit cells
Answer:
C
Question:
8. A patient is receiving the drug warfarin, a drug with a strong attraction to albumin. While taking the
warfarin, the patient begins to take a second drug that also has a strong attraction to albumin. The nurse
would need to watch the patient for signs of:
A)decreased effects of the warfarin because the second drug may cause the warfarin to bind more strongly
to the albumin
B)toxic levels of warfarin because the second drug may displace the warfarin from the albumin
C)subtherapeutic levels of warfarin because the second drug may displace the warfarin from the albumin
D)increased effects of the warfarin because the second drug may cause the warfarin to bind more strongly
to the albumin
Answer:
B
,Question:
9. A patient has been taking a medication to prevent seizures. What is the best rationale for measuring
therapeutic drug levels?
A)There is a direct correlation between therapeutic and toxic levels for most drugs
B)Plasma drug levels are better indicators of drug efficacy than are clinical symptoms.
C)Drug levels that are within the therapeutic range cannot be associated with toxicity.
D)Drug levels below the therapeutic range can never be effective.
Answer:
A
Question:
10. Which of the following is a true statement in regard to pH-dependent ionization?
A)Bases will ionize in an alkaline medium.
B)Medications are not affected by the surrounding pH in body tissues.
C)Acids will ionize best in an acidic medium.
D)An acid is a proton donor, while a base is a proton acceptor.
Answer:
D
Question:
11. The binding of a drug to its receptor is _______ reversible.
A)rarely
B)never
C)usually
D)always
Answer:
C
Question:
12. The majority of drug metabolism is catalyzed by the cytochrome P450 group of liver enzymes. When
these enzymes are inhibited, a drug given simultaneously will:
A)have no effect in the body
B)create the potential for anaphylaxis
C)be inhibited, and levels in the body will drop
D)reach higher-than-intended levels in the body
Answer:
D
Question:
13. Most people who receive a neuromuscular blocker during surgery have a brief response lasting only a
few minutes. A person who has a very prolonged effect from the drug at a standard dosage is experiencing:
A)a physical dependence
B)an idiosyncratic effect
C)an anaphylactic reaction
D)an iatrogenic response
Answer:
B
, Question:
14. When determining whether an adverse drug reaction has occurred, the nurse should consider which
question?
A)Could the pathophysiologic events of the illness itself explain the effect?
B)Is the patient complaining about the frequency of drug dosing?
C)Has the drug produced this effect in another patient receiving the same agent at the same dose?
D)Did the patient notice that the drug caused a bad taste in the mouth?
Answer:
A
Question:
15. Select the accurate statement regarding gender differences in response to drugs.
A)Women are inefficient metabolizers of drugs, and will be more prone to side effects.
B)Men metabolize drugs more effectively, and are therefore more likely to experience the intended drug
effect.
C)Men and women may respond differently to drugs, but little is known about how and why.
D)Gender has no effect on drug kinetics or dynamics.
Answer:
C
Question:
16. A drug given by which of the following routes would be most likely to exhibit the first-pass effect?
A)subcutaneous
B)intravenous
C)oral
D)sublingual
Answer:
C
Question:
17. When discussing the concept of drug tolerance, the nurse should include the fact that
A)addiction is likely to develop if the drug is not tapered
B)this means that the patient will require more drug to achieve the same effect
C)the phenomenon only occurs with opioid medications
D)the patient requires a stable dose of medication until the drug is discontinued
Answer:
B
Question:
18. Which of the following drugs will cross the placenta most readily?
A)Highly polar drugs
B)Ionized drugs
C)Lipid-soluble drugs
D)Protein-bound drugs
Answer:
C