MIDTERM EXAM
Exam-Style Qs that mirror the Exam
Advanced Pathophysiology
Chamberlain
This Document Description:
• Exam-Style Qs that mirror the actual Advanced
Pathophysiology Exam at Chamberlain.
• Designed for advanced nursing students preparing for the
MIDTERM
,Which of the following client(s) should the nurse practitioner (NP) recognize as
being at risk for developing folate deficiency? Select all that apply.
A 30-year-old client with severe anorexia nervosa
A 19-year-old client with sickle cell disease
A 27-year-old client who is newly pregnant and breastfeeding their toddler
A 40-year-old client with celiac disease
A 32-year-old client who had a gastrectomy one year ago
A 30-year-old client with severe anorexia nervosa
A 27-year-old client who is newly pregnant and breastfeeding their toddler
A 40-year-old client with celiac disease
What medications impact the absorption of B12
Metformin, H2 receptor blockers, PPI
What medications impact the absorption of folate anticonvulsants
and methotrexate
A nurse practitioner (NP) evaluates a 45-year-old client who presents with fatigue
and weakness. The NP diagnoses the client with anemia of chronic disease. What is
the primary pathophysiological mechanism causing this normocytic anemia?
Excessive blood loss
Defective erythropoiesis
Impaired iron absorption
Delayed maturation of erythrocyte precursors
Defective erythropoiesis
A nurse practitioner (NP) evaluates a 28-year-old client who presents with fatigue,
jaundice, and dark-colored urine. The NP diagnoses the client with hemolytic
anemia. What is the most likely pathophysiological mechanism causing this
normocytic anemia?
Impaired iron absorption
Excessive blood loss
Defective erythropoiesis
Increased red blood cell destruction
,Increased red blood cell destruction
Which client should the nurse practitioner (NP) recognize as most at risk for
developing hemolytic anemia?
60-year-old with a history of iron-deficiency anemia
35-year-old who recently underwent surgery for a bleeding ulcer
50-year-old who experienced a transfusion reaction after a blood transfusion
28-year-old with a family history of thalassemia
50-year-old who experienced a transfusion reaction after a blood transfusion
The nurse practitioner (NP) evaluates a 30-year-old client with chronic kidney
disease who presents with fatigue, weakness, and pallor. The laboratory results reveal
a low hemoglobin, increased c-reactive protein, and increased erythrocyte
sedimentation rate. The NP anticipates which additional laboratory finding?
Reticulocyte count is not relevant to anemia assessment
Decreased reticulocytes
Increased reticulocytes
Normal reticulocyte count
Decreased reticulocytes
A nurse practitioner (NP) is evaluating a client with a history of chronic kidney
disease who reports symptoms of fatigue, weakness, and occasional shortness of
breath. The client notes a gradual onset of these symptoms over the past few
months. Which laboratory test(s) should the NP order? Select all that apply.
C-reactive protein
Erythrocyte sedimentation rate
Ferritin level
Basic metabolic panel
Complete blood count
C-reactive protein
Erythrocyte sedimentation rate
Ferritin level
Complete blood count Hemolytic anemia labs low
H&H, high bili, high reticulocytes, pos Coombs
, Which of the following best describes the primary pathophysiological mechanism
underlying sickle cell disease?
Altered synthesis of hemoglobin due to a mutation in the beta-globin gene
Impaired immune response leading to frequent infections
Abnormal clotting leading to vascular occlusion
Dysregulated iron metabolism causing excessive iron deposition Altered
synthesis of hemoglobin due to a mutation in the beta-globin gene
which of these Findings are Consistent With Sickle Cell Disease Anemia?
Joint pain
Migraine headache
Joint swelling
Restricted range of motion Pallor
Joint pain
Joint swelling
Restricted range of motion Pallor
The nurse practitioner (NP) is counseling the parents of a child with sickle cell
disease. Which of the following topics should the NP plan to include when
educating the parents? Select all that apply.
Hydroxyurea therapy
Blood transfusion schedule
Homeopathic remedies for a cure
Vaccination schedule
Pain management strategies
Hydroxyurea therapy
Blood transfusion schedule
Vaccination schedule
Pain management strategies
A 28-year-old client with a history of sickle cell anemia presents to the emergency
department with severe pain in the joints and abdomen, decreased range of motion
in extremities, and decreased oxygen saturation levels. The client denies recent
infections. The nurse practitioner (NP) should recognize the client is most likely
experiencing which type of sickle cell crisis?