EXAM 2
Psychopharmacology
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Wilkes University
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NSG 552 Exam 2 .................................................... 2
NSG 552 Exam 2 Study Guide ............................. 45
NSG 552 Exam 2
Question 1 [Case-Based Scenario]
A 22-year-old female with Anorexia Nervosa is admitted to an inpatient
psychiatric unit. She reports severe anxiety before meals and refuses to eat due
to intense fear of weight gain. The psychiatrist considers pharmacologic
intervention. Which medication is most appropriate to administer as a pre-meal
anxiolytic to decrease anticipatory anxiety?
• A. Fluoxetine 20 mg daily
• B. Lorazepam 0.5 mg PRN before meals
• C. Olanzapine 5 mg daily
• D. Buspirone 10 mg BID
Correct Answer: B. Lorazepam 0.5 mg PRN before meals
Rationale: Lorazepam is a short-acting benzodiazepine commonly used as a pre-
meal anxiolytic in Anorexia Nervosa to reduce anticipatory anxiety. It has a rapid
onset and can be given PRN. SSRIs like fluoxetine take weeks to work and are not
appropriate for acute anxiety. Olanzapine is used for severe preoccupation with
, weight and food, not acute anxiety. Buspirone has a slow onset and is not useful
for PRN anxiety relief.
Question 2 [Select All That Apply (SATA)]
A 19-year-old female with Anorexia Nervosa has been hospitalized for severe
malnutrition and obsessive preoccupation with food and body weight. Her BMI is
14.2. The treatment team is considering pharmacologic options. Select all that
apply regarding appropriate medication management for this patient.
• A. Olanzapine may be prescribed to reduce severe preoccupation with weight
and food
• B. Fluoxetine is FDA-approved for Anorexia Nervosa
• C. A pre-meal benzodiazepine such as lorazepam may reduce anticipatory
anxiety
• D. Bupropion is contraindicated due to seizure risk in malnourished patients
• E. Mirtazapine is first-line for weight restoration in Anorexia Nervosa
Correct Answer: A, C, D
Rationale: Olanzapine (A) is used off-label for severe preoccupation with weight
and food in Anorexia Nervosa. A pre-meal benzodiazepine like lorazepam (C) can
help with anticipatory anxiety. Bupropion (D) is contraindicated in eating
disorders due to increased seizure risk, especially in malnourished patients.
Fluoxetine (B) is NOT FDA-approved for Anorexia Nervosa—it is approved for
Bulimia Nervosa. Mirtazapine (E) is not first-line for weight restoration, though it
may be used adjunctively.
Question 3 [Single Best Answer]
Which of the following medications is FDA-approved for the treatment of Bulimia
Nervosa?
• A. Sertraline (Zoloft)