,TEST BANK
Applied Pathophysiology for the Advanced Practice Nurse
2nd Edition by Lucie Dlugasch & Lachel Story
Complete Guide with Rationales – 350 Questions
TABLE OF CONTENTS
Chapter Content Area Questions
Chapter 1 Cellular Function 1-35
Chapter 2 Immunity 36-60
Chapter 3 Inflammation and Wound Healing 61-80
Chapter 4 Genetic and Congenital Disorders 81-95
Chapter 5 Neoplasia 96-115
Chapter 6 Fluid, Electrolyte, and Acid-Base Balance 116-140
Chapter 7 Cardiovascular System 141-180
Chapter 8 Respiratory System 181-210
Chapter 9 Neurological System 211-240
Chapter 10 Gastrointestinal System 241-265
Chapter 11 Renal and Urinary System 266-285
Chapter 12 Endocrine System 286-310
Chapter 13 Musculoskeletal System 311-330
Chapter 14 Reproductive System 331-350
,CHAPTER 1: CELLULAR FUNCTION
Questions 1-35
Question 1
The nucleus, which is essential for function and survival of the cell:
A. Is the site of protein synthesis
B. Contains the genetic code
C. Transforms cellular energy
D. Initiates aerobic metabolism
Correct Answer: B
Rationale: The nucleus contains the genetic code (DNA) that directs cellular activities and
replication . Protein synthesis (A) occurs at ribosomes. Cellular energy transformation (C)
and aerobic metabolism (D) occur in mitochondria.
Question 2
Although energy is not made in mitochondria, they are known as the power plants of the
cell because they:
A. Contain RNA for protein synthesis
B. Utilize glycolysis for oxidative energy
C. Extract energy from organic compounds
D. Store calcium bonds for muscle contractions
Correct Answer: C
Rationale: Mitochondria are the "power plants" of the cell because they extract energy
from organic compounds through oxidative phosphorylation to produce ATP . RNA for
protein synthesis (A) is found in ribosomes. Glycolysis (B) occurs in the cytoplasm. Calcium
storage (D) is a function of the sarcoplasmic reticulum.
Question 3
, Although the basic structure of the cell plasma membrane is formed by a lipid bilayer, most
of the specific membrane functions are carried out by:
A. Bound and transmembrane proteins
B. Complex, long carbohydrate chains
C. Surface antigens and hormone receptors
D. A gating system of selective ion channels
Correct Answer: A
Rationale: Bound and transmembrane proteins carry out most specific membrane
functions, including transport, signaling, and cell adhesion . Carbohydrate chains (B)
contribute to cell recognition. Surface antigens and receptors (C) and ion channels (D) are
specific types of membrane proteins.
Question 4
To effectively relay signals, cell-to-cell communication utilizes chemical messenger systems
that:
A. Displace surface receptor proteins
B. Accumulate within cell gap junctions
C. Bind to contractile microfilaments
D. Release secretions into extracellular fluid
Correct Answer: D
Rationale: Cell-to-cell communication uses chemical messengers that are released into the
extracellular fluid to bind to receptors on target cells . Displacing receptors (A),
accumulating in gap junctions (B), and binding to microfilaments (C) do not describe
chemical messenger signaling.
Question 5
Aerobic metabolism, also known as oxidative metabolism, provides energy by:
A. Removing phosphate bonds from ATP
B. Combining hydrogen and oxygen to form water
C. Activating pyruvate stored in the cytoplasm
D. Breaking down glucose to form lactic acid
Applied Pathophysiology for the Advanced Practice Nurse
2nd Edition by Lucie Dlugasch & Lachel Story
Complete Guide with Rationales – 350 Questions
TABLE OF CONTENTS
Chapter Content Area Questions
Chapter 1 Cellular Function 1-35
Chapter 2 Immunity 36-60
Chapter 3 Inflammation and Wound Healing 61-80
Chapter 4 Genetic and Congenital Disorders 81-95
Chapter 5 Neoplasia 96-115
Chapter 6 Fluid, Electrolyte, and Acid-Base Balance 116-140
Chapter 7 Cardiovascular System 141-180
Chapter 8 Respiratory System 181-210
Chapter 9 Neurological System 211-240
Chapter 10 Gastrointestinal System 241-265
Chapter 11 Renal and Urinary System 266-285
Chapter 12 Endocrine System 286-310
Chapter 13 Musculoskeletal System 311-330
Chapter 14 Reproductive System 331-350
,CHAPTER 1: CELLULAR FUNCTION
Questions 1-35
Question 1
The nucleus, which is essential for function and survival of the cell:
A. Is the site of protein synthesis
B. Contains the genetic code
C. Transforms cellular energy
D. Initiates aerobic metabolism
Correct Answer: B
Rationale: The nucleus contains the genetic code (DNA) that directs cellular activities and
replication . Protein synthesis (A) occurs at ribosomes. Cellular energy transformation (C)
and aerobic metabolism (D) occur in mitochondria.
Question 2
Although energy is not made in mitochondria, they are known as the power plants of the
cell because they:
A. Contain RNA for protein synthesis
B. Utilize glycolysis for oxidative energy
C. Extract energy from organic compounds
D. Store calcium bonds for muscle contractions
Correct Answer: C
Rationale: Mitochondria are the "power plants" of the cell because they extract energy
from organic compounds through oxidative phosphorylation to produce ATP . RNA for
protein synthesis (A) is found in ribosomes. Glycolysis (B) occurs in the cytoplasm. Calcium
storage (D) is a function of the sarcoplasmic reticulum.
Question 3
, Although the basic structure of the cell plasma membrane is formed by a lipid bilayer, most
of the specific membrane functions are carried out by:
A. Bound and transmembrane proteins
B. Complex, long carbohydrate chains
C. Surface antigens and hormone receptors
D. A gating system of selective ion channels
Correct Answer: A
Rationale: Bound and transmembrane proteins carry out most specific membrane
functions, including transport, signaling, and cell adhesion . Carbohydrate chains (B)
contribute to cell recognition. Surface antigens and receptors (C) and ion channels (D) are
specific types of membrane proteins.
Question 4
To effectively relay signals, cell-to-cell communication utilizes chemical messenger systems
that:
A. Displace surface receptor proteins
B. Accumulate within cell gap junctions
C. Bind to contractile microfilaments
D. Release secretions into extracellular fluid
Correct Answer: D
Rationale: Cell-to-cell communication uses chemical messengers that are released into the
extracellular fluid to bind to receptors on target cells . Displacing receptors (A),
accumulating in gap junctions (B), and binding to microfilaments (C) do not describe
chemical messenger signaling.
Question 5
Aerobic metabolism, also known as oxidative metabolism, provides energy by:
A. Removing phosphate bonds from ATP
B. Combining hydrogen and oxygen to form water
C. Activating pyruvate stored in the cytoplasm
D. Breaking down glucose to form lactic acid
