Blood Transfusion Competency Exam Prep Bundle 2026 | 250+ Practice
Questions with Verified Answers & Rationales
Question 1
1. Which blood component is most commonly transfused to increase
oxygen-carrying capacity?
A) Platelets
B) Fresh frozen plasma
C) Packed red blood cells (PRBCs)
D) Cryoprecipitate
Answer
Answer C: – Packed red blood cells (PRBCs)
Rationale
PRBCs are transfused to increase the oxygen-carrying capacity of blood in
patients with anemia or acute blood loss. They are the most commonly
transfused blood component. ---
,Question 2
2. What is the primary indication for transfusion of platelets?
A) Anemia
B) Thrombocytopenia or platelet dysfunction
C) Coagulopathy
D) Hypovolemia
Answer
Answer B: – Thrombocytopenia or platelet dysfunction
Rationale
Platelets are transfused to prevent or treat bleeding in patients with
thrombocytopenia (low platelet count) or platelet dysfunction. ---
Question 3
3. Which blood product is used to replace clotting factors in patients with
coagulopathy?
A) Packed red blood cells
B) Platelets
C) Fresh frozen plasma (FFP)
D) Cryoprecipitate
Answer
,Answer C: – Fresh frozen plasma (FFP)
Rationale
FFP contains all coagulation factors and is used to treat coagulopathy in
patients with liver disease, DIC, or massive transfusion. ---
Question 4
4. What is the primary indication for cryoprecipitate transfusion?
A) Anemia
B) Fibrinogen deficiency or factor VIII deficiency
C) Thrombocytopenia
D) Hypovolemia
Answer
Answer B: – Fibrinogen deficiency or factor VIII deficiency
Rationale
Cryoprecipitate is rich in fibrinogen, factor VIII, and von Willebrand factor. It
is used to treat fibrinogen deficiency and factor VIII deficiency. ---
Question 5
5. Which blood component is indicated for volume expansion in patients
with hypovolemic shock?
, A) Platelets
B) Fresh frozen plasma
C) Cryoprecipitate
D) Packed red blood cells (when oxygen-carrying capacity is needed)
Answer
Answer D: – Packed red blood cells (when oxygen-carrying capacity is
needed)
Rationale
While crystalloids and colloids are first-line for volume expansion, PRBCs are
indicated when volume loss is accompanied by decreased oxygen-carrying
capacity. ---
Question 6
6. Which blood product contains all coagulation factors and is stored
frozen?
A) Cryoprecipitate
B) Fresh frozen plasma (FFP)
C) Platelets
D) Packed red blood cells
Answer
Answer B: – Fresh frozen plasma (FFP)
Questions with Verified Answers & Rationales
Question 1
1. Which blood component is most commonly transfused to increase
oxygen-carrying capacity?
A) Platelets
B) Fresh frozen plasma
C) Packed red blood cells (PRBCs)
D) Cryoprecipitate
Answer
Answer C: – Packed red blood cells (PRBCs)
Rationale
PRBCs are transfused to increase the oxygen-carrying capacity of blood in
patients with anemia or acute blood loss. They are the most commonly
transfused blood component. ---
,Question 2
2. What is the primary indication for transfusion of platelets?
A) Anemia
B) Thrombocytopenia or platelet dysfunction
C) Coagulopathy
D) Hypovolemia
Answer
Answer B: – Thrombocytopenia or platelet dysfunction
Rationale
Platelets are transfused to prevent or treat bleeding in patients with
thrombocytopenia (low platelet count) or platelet dysfunction. ---
Question 3
3. Which blood product is used to replace clotting factors in patients with
coagulopathy?
A) Packed red blood cells
B) Platelets
C) Fresh frozen plasma (FFP)
D) Cryoprecipitate
Answer
,Answer C: – Fresh frozen plasma (FFP)
Rationale
FFP contains all coagulation factors and is used to treat coagulopathy in
patients with liver disease, DIC, or massive transfusion. ---
Question 4
4. What is the primary indication for cryoprecipitate transfusion?
A) Anemia
B) Fibrinogen deficiency or factor VIII deficiency
C) Thrombocytopenia
D) Hypovolemia
Answer
Answer B: – Fibrinogen deficiency or factor VIII deficiency
Rationale
Cryoprecipitate is rich in fibrinogen, factor VIII, and von Willebrand factor. It
is used to treat fibrinogen deficiency and factor VIII deficiency. ---
Question 5
5. Which blood component is indicated for volume expansion in patients
with hypovolemic shock?
, A) Platelets
B) Fresh frozen plasma
C) Cryoprecipitate
D) Packed red blood cells (when oxygen-carrying capacity is needed)
Answer
Answer D: – Packed red blood cells (when oxygen-carrying capacity is
needed)
Rationale
While crystalloids and colloids are first-line for volume expansion, PRBCs are
indicated when volume loss is accompanied by decreased oxygen-carrying
capacity. ---
Question 6
6. Which blood product contains all coagulation factors and is stored
frozen?
A) Cryoprecipitate
B) Fresh frozen plasma (FFP)
C) Platelets
D) Packed red blood cells
Answer
Answer B: – Fresh frozen plasma (FFP)
