Pharmacology Chapter 4
2026-2027 Updated
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, Pharma reps need a solid understanding of 3 things 1.) Anatomy
2.) Physiology
3.) Clinical pharmacology
Anatomy the study of the basic structures of the body
Physiology the study of how those body structures function
Clinical Pharmacology study of the effects and movement of drugs in the human body
How many prescriptions dispensed each year in the US? more than 3 billion
the ____ recorded the earliest surviving prescriptions Babylonians
Pen Tsao (Great Herbal)
-recorded by the chinese and it was a 40 volume compendium of plant remedies
dating to 2700BC
Ebers Papyrus Egyptian archived remedies dating back to 1500BC
Fredrich Serturner first isolated morphine in 1805 and injected it into himself and 3 friends in a huge
dose
John Jacob Abel father of American pharmacology
University of Michigan in 1890
Basic clinical pharmacology involves three main 1.) Pharmacodynamics
concepts 2.) Pharmacokinetics
3.) drug distribution and elimination
Pharmacodynamics study of biochemical and physiological effects of drugs and their mechanisms of
action
ie: study of what drugs do to the body
Pharmacokinetics Study of how a drug is processed by the body, with emphasis on the time
required for absorption, duration of action, distribution, and method of excretion
ie: study of how the body effects drugs
Drug (defined by US law) and substance (other than food or device intended for use in the diagnosis, cure,
relief, treatment, or prevention of disease) intended to affect the structure or
function of the body.
simple definition: any chemical substance that affects the body and its processes
Drugs divided into 2 categories prescription and non-prescription drugs