Assessment 3.1 2025/2026 Verified Practice Questions with
Answers & Detailed Rationales | Complete Study Guide for OB
Medication Math & IV Flow Rates
INTRODUCTION
This comprehensive study guide features verified practice questions
covering the most frequently tested topics on the ATI Dosage Calculation
RN Maternal Newborn Proctored Assessment 3.1, including oral and
injectable medication calculations, IV infusion flow rates, weight-based
dosing, newborn and postpartum medication administration, and
medication safety principles . Each question includes the correct answer
in bold italics with a detailed rationale explaining the step-by-step
calculation method and clinical considerations, following ATI testing
standards and NCLEX-RN guidelines. Based on the latest 2025/2026
examination content, this resource is designed for nursing students to
master maternal-newborn dosage calculations and successfully pass the
ATI proctored assessment with confidence.
,SECTION 1: ORAL & INJECTABLE MEDICATION DOSAGE CALCULATIONS
Question 1
A nurse is preparing to administer docusate sodium PO to a postpartum
client who has a prescription for 200 mg/day in two equally divided
doses. The client states she has trouble swallowing tablets and capsules.
Therefore, the nurse has obtained docusate sodium liquid 50 mg/5 mL.
How many mL should the nurse administer per dose?
A) 5 mL
B) 10 mL
C) 15 mL
D) 20 mL
Answer: B) 10 mL
Explanation: Step 1: Determine the amount needed per dose. Total daily
dose is 200 mg divided into two doses = 100 mg per dose. Step 2: Use the
formula: Desired dose ÷ Available dose × Volume. (100 mg ÷ 50 mg) × 5
mL = 2 × 5 mL = 10 mL. The nurse should administer 10 mL of docusate
sodium liquid per dose .**
Question 2
A nurse is preparing to administer enoxaparin 55 mg subcutaneously to a
client who has a deep-vein thrombosis after undergoing a cesarean birth.
,Available is enoxaparin solution for injection 60 mg/0.6 mL. How many mL
should the nurse administer?
A) 0.5 mL
B) 0.55 mL
C) 0.6 mL
D) 0.65 mL
Answer: C) 0.6 mL
Explanation: Use the proportion method: 60 mg / 0.6 mL = 55 mg / X mL.
Cross-multiply: 60X = 55 × 0.6 = 33. X = 33 ÷ 60 = 0.55 mL. Round to the
nearest tenth = 0.6 mL .**
Question 3
A nurse is preparing to administer ferrous sulfate 120 mg PO two times
each day with meals to a client who is at 12 weeks of gestation and has
anemia. Available is ferrous sulfate syrup 90 mg/5 mL. How many mL
should the nurse administer per dose?
A) 5.7 mL
B) 6.0 mL
C) 6.7 mL
D) 7.0 mL
Answer: C) 6.7 mL
, Explanation: Use the formula: Desired dose ÷ Available dose × Volume.
(120 mg ÷ 90 mg) × 5 mL = 1.333 × 5 mL = 6.67 mL. Round to the nearest
tenth = 6.7 mL .**
Question 4
A nurse is preparing to administer iron polysaccharide 100 mg PO.
Available is iron polysaccharide 50 mg tablets. How many tablets should
the nurse administer?
A) 1 tablet
B) 1.5 tablets
C) 2 tablets
D) 2.5 tablets
Answer: C) 2 tablets
Explanation: Number of tablets = Desired dose ÷ Available dose per
tablet. 100 mg ÷ 50 mg/tablet = 2 tablets .**
Question 5
A nurse is preparing to administer acyclovir 400 mg PO to a client who
has herpes simplex type 2 virus. Available is acyclovir 200 mg capsules.
How many capsules should the nurse administer?
A) 1 capsule
B) 2 capsules