NR 565 MIDTERM EXAM ACTUAL EXAM 2026 | ADVANCED
PHARMACOLOGY MIDTERM EXAM || MOST RECENT EXAM
2026|2027 ACTUAL COMPLETE REAL EXAM QUESTIONS
AND CORRECT ANSWERS (VERIFIED ANSWERS) ALREADY
GRADED A+ | GUARANTEED SUCCESS!! NEWEST EXAM |
JUST RELEASED!! CHAMBERLAIN
A patient with hypertension is prescribed Lisinopril. Which
mechanism best describes the therapeutic action of this medication?
A. Direct relaxation of vascular smooth muscle
B. Inhibition of angiotensin-converting enzyme
C. Blockade of beta-1 adrenergic receptors
D. Inhibition of calcium influx into vascular smooth muscle
Answer: B. Inhibition of angiotensin-converting enzyme
Rationale: Lisinopril is an ACE inhibitor. It decreases conversion of
angiotensin I to angiotensin II, reducing vasoconstriction and
aldosterone secretion. This lowers blood pressure and decreases sodium
and water retention.
Question 2
Which adverse effect is most characteristic of ACE inhibitors?
A. Persistent dry cough
B. Severe constipation
C. Hypoglycemia
D. Hearing loss
Answer: A. Persistent dry cough
,Rationale: ACE inhibitors increase bradykinin concentrations, which
can produce a persistent, nonproductive cough. Angioedema is another
important adverse effect requiring immediate evaluation.
Question 3
A patient taking Lisinopril develops swelling of the lips and tongue.
What is the nurse's priority action?
A. Administer the next dose with food
B. Encourage increased fluid intake
C. Recognize possible angioedema and obtain emergency treatment
D. Reassure the patient that this is an expected effect
Answer: C. Recognize possible angioedema and obtain emergency
treatment
Rationale: ACE-inhibitor-associated angioedema can rapidly
compromise the airway. The medication should be discontinued and
emergency management initiated when significant facial, tongue, or
airway swelling occurs.
Question 4
Which medication class is generally contraindicated during pregnancy
because of potential fetal renal injury?
A. ACE inhibitors
B. Proton pump inhibitors
,C. H2-receptor antagonists
D. Antacids
Answer: A. ACE inhibitors
Rationale: ACE inhibitors can cause serious fetal renal abnormalities,
oligohydramnios, and other adverse fetal outcomes. They should not be
used during pregnancy.
Question 5
A patient taking hydrochlorothiazide should be monitored particularly
closely for which electrolyte abnormality?
A. Hyperkalemia
B. Hypokalemia
C. Hypomagnesemia
D. Hypernatremia
Answer: B. Hypokalemia
Rationale: Hydrochlorothiazide is a thiazide diuretic that increases
urinary sodium and water excretion and can increase potassium loss.
Serum electrolytes should therefore be monitored.
Question 6
Which laboratory value is most important to monitor in a patient
taking spironolactone?
, A. Potassium
B. Calcium
C. Hemoglobin
D. Platelets
Answer: A. Potassium
Rationale: Spironolactone is a potassium-sparing diuretic and
aldosterone antagonist. It can cause hyperkalemia, particularly in
patients with renal impairment or those taking other medications that
increase potassium.
Question 7
Which finding would be most concerning in a patient taking
spironolactone?
A. Mild thirst
B. Potassium level of 6.1 mEq/L
C. Increased urination
D. Mild fatigue after exercise
Answer: B. Potassium level of 6.1 mEq/L
Rationale: A potassium level of 6.1 mEq/L represents significant
hyperkalemia and can produce potentially fatal cardiac dysrhythmias.
Immediate evaluation and management are warranted.
Question 8
PHARMACOLOGY MIDTERM EXAM || MOST RECENT EXAM
2026|2027 ACTUAL COMPLETE REAL EXAM QUESTIONS
AND CORRECT ANSWERS (VERIFIED ANSWERS) ALREADY
GRADED A+ | GUARANTEED SUCCESS!! NEWEST EXAM |
JUST RELEASED!! CHAMBERLAIN
A patient with hypertension is prescribed Lisinopril. Which
mechanism best describes the therapeutic action of this medication?
A. Direct relaxation of vascular smooth muscle
B. Inhibition of angiotensin-converting enzyme
C. Blockade of beta-1 adrenergic receptors
D. Inhibition of calcium influx into vascular smooth muscle
Answer: B. Inhibition of angiotensin-converting enzyme
Rationale: Lisinopril is an ACE inhibitor. It decreases conversion of
angiotensin I to angiotensin II, reducing vasoconstriction and
aldosterone secretion. This lowers blood pressure and decreases sodium
and water retention.
Question 2
Which adverse effect is most characteristic of ACE inhibitors?
A. Persistent dry cough
B. Severe constipation
C. Hypoglycemia
D. Hearing loss
Answer: A. Persistent dry cough
,Rationale: ACE inhibitors increase bradykinin concentrations, which
can produce a persistent, nonproductive cough. Angioedema is another
important adverse effect requiring immediate evaluation.
Question 3
A patient taking Lisinopril develops swelling of the lips and tongue.
What is the nurse's priority action?
A. Administer the next dose with food
B. Encourage increased fluid intake
C. Recognize possible angioedema and obtain emergency treatment
D. Reassure the patient that this is an expected effect
Answer: C. Recognize possible angioedema and obtain emergency
treatment
Rationale: ACE-inhibitor-associated angioedema can rapidly
compromise the airway. The medication should be discontinued and
emergency management initiated when significant facial, tongue, or
airway swelling occurs.
Question 4
Which medication class is generally contraindicated during pregnancy
because of potential fetal renal injury?
A. ACE inhibitors
B. Proton pump inhibitors
,C. H2-receptor antagonists
D. Antacids
Answer: A. ACE inhibitors
Rationale: ACE inhibitors can cause serious fetal renal abnormalities,
oligohydramnios, and other adverse fetal outcomes. They should not be
used during pregnancy.
Question 5
A patient taking hydrochlorothiazide should be monitored particularly
closely for which electrolyte abnormality?
A. Hyperkalemia
B. Hypokalemia
C. Hypomagnesemia
D. Hypernatremia
Answer: B. Hypokalemia
Rationale: Hydrochlorothiazide is a thiazide diuretic that increases
urinary sodium and water excretion and can increase potassium loss.
Serum electrolytes should therefore be monitored.
Question 6
Which laboratory value is most important to monitor in a patient
taking spironolactone?
, A. Potassium
B. Calcium
C. Hemoglobin
D. Platelets
Answer: A. Potassium
Rationale: Spironolactone is a potassium-sparing diuretic and
aldosterone antagonist. It can cause hyperkalemia, particularly in
patients with renal impairment or those taking other medications that
increase potassium.
Question 7
Which finding would be most concerning in a patient taking
spironolactone?
A. Mild thirst
B. Potassium level of 6.1 mEq/L
C. Increased urination
D. Mild fatigue after exercise
Answer: B. Potassium level of 6.1 mEq/L
Rationale: A potassium level of 6.1 mEq/L represents significant
hyperkalemia and can produce potentially fatal cardiac dysrhythmias.
Immediate evaluation and management are warranted.
Question 8
