HUETHER AND MCCANCES
UNDERSTANDING PATHOPHYSIOLOGY
CANADIAN EDITION SECOND EDITION
KELLY POWER KEAN EXAM REVIEW
VERIFIED QUESTIONS WITH DETAILED
ANSWERS STUDY RESOURCE GRADED A+
⩥ Eosinopenia is caused by.
Answer: migration of cells into inflammatory sites
Other causes- surgery, shock, trauma, burns or mental distress
⩥ What causes basophilia?.
Answer: response to inflammation secondary to infection (e.g.measles,
chickenpox) and hypersensitivity
⩥ What causes basopenia?.
Answer: acute infection, hyperthyroidism, pregnancy, stress and long-
term steroid use
⩥ What causes monocytosis?.
Answer: bacterial infection (e.g.tuberculosis, subacute bacterial
endocarditis) or hematological disorders (e.g. myeloproliferative
,disorders, hodgkin disease, or agranulocytosis). Poor indicator of
disease.
⩥ Monocytopenia.
Answer: rare and usually indicates hairy cell leukemia or prednisone
therapy
⩥ Lymphocytosis is most commonly caused in response to.
Answer: viral infection (Epstein-Barr)
⩥ Lymphocytopenia.
Answer: Associated with neoplasia and immune deficiencies, destruction
by drugs, radiation, or viruses. May be idiopathic. Major problem in
AIDS.
⩥ Mononucleosis.
Answer: Acute infection of B lymphocytes (B cells) with Epstein-Barr
virus transmitted by saliva. It's most common in children, adolescents,
and young adults. Incubation time is usually 30-50 days.
⩥ What are manifestations of mononucleosis?.
Answer: Fever, sore throat, cervical lymph node enlargement, fatigue
and increase lymphocyte count. In rare cases, liver and spleen
, enlargement may lead to rupture which is life threatening. (lymphocytes
usually go through apoptosis in the spleen)
⩥ How is mononucleosis diagnosed?.
Answer: monospot qualitative test for heterophilic antibodies
⩥ How is mononucleosis treated?.
Answer: Supportive care with analgesics and antipyretics. Severe cases
may require antivirals
⩥ Leukemia.
Answer: Neoplastic proliferation of leukocyte precursors in the bone
marrow. Classification depends on (1) the type of cell of origin (myeloid
or lymphoid) and (2) the rate of progression (acute or chronic) Anemia
result from suppressed red blood cells and platelet production
⩥ Acute Leukemia.
Answer: presence of undifferentiated or immature cells, usually blast
cells
⩥ Acute lymphocytic leukemia (ALL) is most common in.
Answer: Children
⩥ What are manifestations of acute lymphocytic anemia?.
UNDERSTANDING PATHOPHYSIOLOGY
CANADIAN EDITION SECOND EDITION
KELLY POWER KEAN EXAM REVIEW
VERIFIED QUESTIONS WITH DETAILED
ANSWERS STUDY RESOURCE GRADED A+
⩥ Eosinopenia is caused by.
Answer: migration of cells into inflammatory sites
Other causes- surgery, shock, trauma, burns or mental distress
⩥ What causes basophilia?.
Answer: response to inflammation secondary to infection (e.g.measles,
chickenpox) and hypersensitivity
⩥ What causes basopenia?.
Answer: acute infection, hyperthyroidism, pregnancy, stress and long-
term steroid use
⩥ What causes monocytosis?.
Answer: bacterial infection (e.g.tuberculosis, subacute bacterial
endocarditis) or hematological disorders (e.g. myeloproliferative
,disorders, hodgkin disease, or agranulocytosis). Poor indicator of
disease.
⩥ Monocytopenia.
Answer: rare and usually indicates hairy cell leukemia or prednisone
therapy
⩥ Lymphocytosis is most commonly caused in response to.
Answer: viral infection (Epstein-Barr)
⩥ Lymphocytopenia.
Answer: Associated with neoplasia and immune deficiencies, destruction
by drugs, radiation, or viruses. May be idiopathic. Major problem in
AIDS.
⩥ Mononucleosis.
Answer: Acute infection of B lymphocytes (B cells) with Epstein-Barr
virus transmitted by saliva. It's most common in children, adolescents,
and young adults. Incubation time is usually 30-50 days.
⩥ What are manifestations of mononucleosis?.
Answer: Fever, sore throat, cervical lymph node enlargement, fatigue
and increase lymphocyte count. In rare cases, liver and spleen
, enlargement may lead to rupture which is life threatening. (lymphocytes
usually go through apoptosis in the spleen)
⩥ How is mononucleosis diagnosed?.
Answer: monospot qualitative test for heterophilic antibodies
⩥ How is mononucleosis treated?.
Answer: Supportive care with analgesics and antipyretics. Severe cases
may require antivirals
⩥ Leukemia.
Answer: Neoplastic proliferation of leukocyte precursors in the bone
marrow. Classification depends on (1) the type of cell of origin (myeloid
or lymphoid) and (2) the rate of progression (acute or chronic) Anemia
result from suppressed red blood cells and platelet production
⩥ Acute Leukemia.
Answer: presence of undifferentiated or immature cells, usually blast
cells
⩥ Acute lymphocytic leukemia (ALL) is most common in.
Answer: Children
⩥ What are manifestations of acute lymphocytic anemia?.
