Wgu D Actual Exam Questions And Correct Detailed Answers With Rationales

WGU D027 2025-2026 ACTUAL EXAM
QUESTIONS AND CORRECT DETAILED
ANSWERS WITH RATIONALES
What organ does cystic fibrosis affect? - ANSWERS-
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Affects the pancreas causing secretions into the lungs
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What is Klinefelter syndrome? - ANSWERS-
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An extra X chromosome for males so example XXY causing female-like qualities
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What is Turner Syndrome? - ANSWERS-
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females. missing or deformed x chromosome. right hemisphere dysfunction, hearing l
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oss, ear infection, language and articulation disorders, visual spatial and attentional pr
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oblems

What is beta thalassemia? - ANSWERS-
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a condition in which the synthesis of the beta-
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globin chains is decreased or absent. Causes low hemoglobin.
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Which medication is contraindicated in a patient with Beta Thalassemia? -
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ANSWERS-Ferrous Sulfate
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What drug is used in combination with other agent to treat lymphoid tissue (leukemia).
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Directly toxic to lymphoid tissues Selective estrogen receptor modulators (SERM) -
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for hormone receptor positive and advanced breast cancer. (Tomaxafin -
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reduces risk and recurrence risk) - ANSWERS-Glucocorticoids
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What is the normal ejection fraction? - ANSWERS-55-60%. Less than 50% is BAD
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Is an ejection fraction of 50% reduced or preserved? - ANSWERS-Preserved
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What are symptoms of left sided heart failure? - ANSWERS-
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Think PULMONARY. JVD, FVO, rails, S3 murmurs. Number one cause of right sided
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heart failure! jv




What are symptoms of right sided heart failure? - ANSWERS-
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Think peripheral vascular. Lower extremity edema, abdominal distension.
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What is the gold standard lab test for heart failure? - ANSWERS-
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BNP. Heart failure is a result greater than 100
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What heart disease is worse with exertion? - ANSWERS-
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Ischemic heart disease because the demand requirements are higher.
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What should you assess before giving Digoxin? - ANSWERS-Apical pulse
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, How should Warfarin be started? - ANSWERS-
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Start initial dose at half to monitor the effects
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What causes the destruction of alveolar walls?
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Air goes in but can't get out which leads to hyperinflation - ANSWERS-Emphysema
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What causes excess mucus production and smooth muscle hypertrophy? -
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ANSWERS-Bronchitis
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What is a chronic inflammatory obstruction of bronchi? - ANSWERS-
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Asthma, Triggers cause mucus to clog bronchial tubes.
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What causes an overbite and buffalo hump? - ANSWERS-
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Endocrine disorder called acromegaly (overproduction of growth hormone)
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What causes Addison's disease? - ANSWERS-
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Decreased glucocorticoid (due to autoimmune destruction of adrenal cortex)
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What causes Cushing's syndrome? - ANSWERS-excess cortisol
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What causes Grave's disease? - ANSWERS-
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overproduction of thyroid hormone. HYPERthyroidism. jv jv jv jv




When should you instruct the patient to take their FIRST dose of antihypertensive? -
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ANSWERS-
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At night to avoid orthostatic hypotension. Educate slow position changes and lay dow
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n if needed.
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What are side effects of ACE inhibitors? - ANSWERS-dry cough
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angioedema
hyperkalemia
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Which type of antihypertensive should NOT be given to patients with Asthma? -
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ANSWERS-Nonselective beta blocker (-lol) because both beta-
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2 receptors are effected
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What is the first choice of calcium channel blocker? - ANSWERS-Verapamil
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What side effect should you watch for in a patient taking a statin drug? - ANSWERS-
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Muscle pain which can lead to rhabdomyolysis, kidney failure, and death.
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Which diuretic is NOT used in patients with kidney failure and sickle cell disease? -
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ANSWERS-Thiazide diuretics
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What type of drug is spironolactone? - ANSWERS-potassium sparing diuretic
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Which type of insulin is the most painful during injection? - ANSWERS-Lantus (long-
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acting)