NAPLEX Review 2026 | Questions & Answers |
Latest Update | Exam Prep | 100% Pass
Guarantee
What is the equation for corrected phenytoin? - correct AnswersCP= measured serum
phenytoin/(0.2*albumin)+0.1
What is the principle intracellular cation? - correct Answerspotassium
Principle extracellular is Sodium
How many mL in a teaspoon? - correct Answers5 mL
how many mL in a tablespoon - correct Answers15 mL
how many mL in a cup? - correct Answers240 mL
how many mL in an ounce? - correct Answers29.6 mL
how many mL in a pint? - correct Answers473 mL
how many mL in a gallon? - correct Answers3785 mL
How do we calculate mols or mmols of a substance? - correct Answersmol= g/MW
mmol= mg/MW
How many mg are in one grain? - correct Answers65 mg/grain
How many lbs in a kg? - correct Answers2.2lbs/kg
What is the conversion of aminophylline to theophylline? - correct Answerswe multiply
the aminophylline by 0.8 to get the equivalent theophylline
What is the conversion of theophylline to aminophylline? - correct Answersdivide the
amount of theophylline by 0.8 to get the equivalent aminophylline
How do we get the ratio strength from the percent strength? - correct Answersratio
strength= 100/% strength
How do we get the percent strength from the ratio strength? - correct Answers%
strength= 100/ratio strength
,How do we convert PPM to percent strength? - correct Answers-PPM to % strength,
move decimal left 4 places
-% strength to PPM, move decimal place right 4 places
specific gravity - correct AnswersSG= grams of substance/mL
mEq - correct AnswersmEq= mg x valence/MW
Which chemicals have 2 valences? - correct AnswersCalcium carbonate
Calcium chloride
Ferrous sulfate
Magnesium sulfate
mOsmol/L - correct AnswersmOsmol/L= [wt of substance (g/L)/MW (g/mole)] x number
of particles x 1000
Equation for anion gap` - correct AnswersNa - (Cl + Bicarbonate)
How much elemental calcium is found in calcium carbonate and calcium citrate? -
correct Answers40% in carbonate
20% in citrate
How much elemental Iron is in ferrous fumarate, ferrous sulfate, and ferrous gluconate?
- correct Answersfumarate: 108 mg
sulfate: 65 mg of 325mg (20%)
gluconate 35 mg
How is absolute neutrophil count calculated? - correct AnswersANC= WBC x [(%segs +
%bands)/100]
What is the formula to determine a patient's total energy expenditure? - correct
AnswersTEE= BEE x activity factor X stress factor
What is the equation to find pH of a weak acid? - correct AnswerspH = pKa +
log(salt/acid)
What is the equation to find pH of a weak base? - correct AnswerspH = (pKw - pKb) +
log(base/salt)
what can we tell about ionization of acids from the pH and the pKa? - correct
AnswerspH > pKa more acid is ionized
pH = pKa ionized and unionized are equal
pH < pKa more acid is unionized
An ionized drug is more soluble but cannot easily cross lipid membranes and vice versa
,How are the ABG measurements written out on the exam? - correct
AnswerspH/pCO2/pO2/HCO3/O2
What are the normal values for pH, HCO3, and pCO2? - correct AnswerspH = 7.35-7.45
HCO3 = 38-42
pCO2 = 22-28
When adding calcium and phosphate to TPN what should be considered? - correct
Answers-Use calcium gluconate over calcium chloride because it is less reactive and a
lower rate of precipitation.
-Add phosphate first then add calcium at the end of the prep
-when added together don't exceed 45 mEq/L
BMI - correct Answersweight in kg/height in meter^2
BSA - correct AnswersBSA = SQR [weight(kg) x height (cm)/3600]
How many kcals are in 10%, 20%, and 30% intravenous fat emulsions? How much fat is
needed for TPN? - correct Answers10% = 1.1 kcal/mL
20% = 2 kcal/mL
30% = 3 kcal/mL
Fat for TPN = 9 kcal/gram
How many kcals do amino acids and dextrose provide in TPN? - correct AnswersAmino
acids 4 kcal/gram
dextrose 3.4 kcal/gram
what is the pKa? - correct AnswersThe pKa is the pH at which half the drug is 50%
ionized. This is half the neutralization or equivalence point. The neutralization or
equivalence point is at a much higher pH and occurs when the acid has been
neutralized.
what is the correct calcium equation? - correct AnswersCorrected Ca = [(4.0-albumin) x
0.8] + serum calcium
What is the equation for absolute bioavailability? - correct AnswersF= 100 x (AUC
extravascular/AUC intravascular) x (Dose intravascular/Dose extravascular)
What is the equation to find the volume of distribution? - correct AnswersVd = amount of
drug given/concentration of drug in plasma
What is the equation for clearance? - correct AnswersCl = rate of
elimination/concentration
Cl = F x Dose/AUC
Cl = Dose/AUC (if bioavailability is 1)
, what is the equation for the elimination rate constant? - correct Answerske =
Clearance/volume of distribution
How do we find the half-life? - correct Answerst1/2 = 0.693/ke
How do we define pharmacodynamics vs. pharmacokinetics? - correct
Answerspharmacodynamics: what the drug does to the body
Pharmacokinetics: what the body does to the drug
Formula to determine patients LDL - correct AnswersLDL = TC - HDL - TG/5
What are glass, wedgwood, and porcelain mortars used for? - correct AnswersGlass-
used for mixing liquids (solutions, suspensions) and oily or staining compounds
Wedgwood- used for grinding dry crystals and hard powders
Porcelain- used to blend powders and pulverize gummy consistencies
What is the Master Formulation Record? - correct Answersrecipe that provides all
ingredients and instructions for preparing a compounded product. includes compound
name, strength, dosage form, all calculations, and everything needed to make the
compound
What is the compounding log? - correct Answersit's the log book of all products made in
the pharmacy
what is a QA plan? - correct Answersquality assurance plan that outlines the steps and
actions that ensure the maintenance of proper standards for compounding preparations.
needs to be reviewed and updated regularly.
ADR of compounded products would be recorded where? - correct AnswersIn the
pharmacy's compounding record
Comminution - correct Answersreduction of solid particles to smaller size by crushing or
grinding
AKA-trituration and levigation
trituration - correct Answersgrinding powders into smaller particles with motor and
pestle
levigation - correct Answerstrituration with liquid to help grinding process.
give an example of a lubricant for non-sterile dry compounding - correct
Answersmagnesium stearate
What is the purpose of a surfactant in regard to dry compounding? Give an example -
correct Answersneutralizes a static charge which keeps the powder from floating away
Latest Update | Exam Prep | 100% Pass
Guarantee
What is the equation for corrected phenytoin? - correct AnswersCP= measured serum
phenytoin/(0.2*albumin)+0.1
What is the principle intracellular cation? - correct Answerspotassium
Principle extracellular is Sodium
How many mL in a teaspoon? - correct Answers5 mL
how many mL in a tablespoon - correct Answers15 mL
how many mL in a cup? - correct Answers240 mL
how many mL in an ounce? - correct Answers29.6 mL
how many mL in a pint? - correct Answers473 mL
how many mL in a gallon? - correct Answers3785 mL
How do we calculate mols or mmols of a substance? - correct Answersmol= g/MW
mmol= mg/MW
How many mg are in one grain? - correct Answers65 mg/grain
How many lbs in a kg? - correct Answers2.2lbs/kg
What is the conversion of aminophylline to theophylline? - correct Answerswe multiply
the aminophylline by 0.8 to get the equivalent theophylline
What is the conversion of theophylline to aminophylline? - correct Answersdivide the
amount of theophylline by 0.8 to get the equivalent aminophylline
How do we get the ratio strength from the percent strength? - correct Answersratio
strength= 100/% strength
How do we get the percent strength from the ratio strength? - correct Answers%
strength= 100/ratio strength
,How do we convert PPM to percent strength? - correct Answers-PPM to % strength,
move decimal left 4 places
-% strength to PPM, move decimal place right 4 places
specific gravity - correct AnswersSG= grams of substance/mL
mEq - correct AnswersmEq= mg x valence/MW
Which chemicals have 2 valences? - correct AnswersCalcium carbonate
Calcium chloride
Ferrous sulfate
Magnesium sulfate
mOsmol/L - correct AnswersmOsmol/L= [wt of substance (g/L)/MW (g/mole)] x number
of particles x 1000
Equation for anion gap` - correct AnswersNa - (Cl + Bicarbonate)
How much elemental calcium is found in calcium carbonate and calcium citrate? -
correct Answers40% in carbonate
20% in citrate
How much elemental Iron is in ferrous fumarate, ferrous sulfate, and ferrous gluconate?
- correct Answersfumarate: 108 mg
sulfate: 65 mg of 325mg (20%)
gluconate 35 mg
How is absolute neutrophil count calculated? - correct AnswersANC= WBC x [(%segs +
%bands)/100]
What is the formula to determine a patient's total energy expenditure? - correct
AnswersTEE= BEE x activity factor X stress factor
What is the equation to find pH of a weak acid? - correct AnswerspH = pKa +
log(salt/acid)
What is the equation to find pH of a weak base? - correct AnswerspH = (pKw - pKb) +
log(base/salt)
what can we tell about ionization of acids from the pH and the pKa? - correct
AnswerspH > pKa more acid is ionized
pH = pKa ionized and unionized are equal
pH < pKa more acid is unionized
An ionized drug is more soluble but cannot easily cross lipid membranes and vice versa
,How are the ABG measurements written out on the exam? - correct
AnswerspH/pCO2/pO2/HCO3/O2
What are the normal values for pH, HCO3, and pCO2? - correct AnswerspH = 7.35-7.45
HCO3 = 38-42
pCO2 = 22-28
When adding calcium and phosphate to TPN what should be considered? - correct
Answers-Use calcium gluconate over calcium chloride because it is less reactive and a
lower rate of precipitation.
-Add phosphate first then add calcium at the end of the prep
-when added together don't exceed 45 mEq/L
BMI - correct Answersweight in kg/height in meter^2
BSA - correct AnswersBSA = SQR [weight(kg) x height (cm)/3600]
How many kcals are in 10%, 20%, and 30% intravenous fat emulsions? How much fat is
needed for TPN? - correct Answers10% = 1.1 kcal/mL
20% = 2 kcal/mL
30% = 3 kcal/mL
Fat for TPN = 9 kcal/gram
How many kcals do amino acids and dextrose provide in TPN? - correct AnswersAmino
acids 4 kcal/gram
dextrose 3.4 kcal/gram
what is the pKa? - correct AnswersThe pKa is the pH at which half the drug is 50%
ionized. This is half the neutralization or equivalence point. The neutralization or
equivalence point is at a much higher pH and occurs when the acid has been
neutralized.
what is the correct calcium equation? - correct AnswersCorrected Ca = [(4.0-albumin) x
0.8] + serum calcium
What is the equation for absolute bioavailability? - correct AnswersF= 100 x (AUC
extravascular/AUC intravascular) x (Dose intravascular/Dose extravascular)
What is the equation to find the volume of distribution? - correct AnswersVd = amount of
drug given/concentration of drug in plasma
What is the equation for clearance? - correct AnswersCl = rate of
elimination/concentration
Cl = F x Dose/AUC
Cl = Dose/AUC (if bioavailability is 1)
, what is the equation for the elimination rate constant? - correct Answerske =
Clearance/volume of distribution
How do we find the half-life? - correct Answerst1/2 = 0.693/ke
How do we define pharmacodynamics vs. pharmacokinetics? - correct
Answerspharmacodynamics: what the drug does to the body
Pharmacokinetics: what the body does to the drug
Formula to determine patients LDL - correct AnswersLDL = TC - HDL - TG/5
What are glass, wedgwood, and porcelain mortars used for? - correct AnswersGlass-
used for mixing liquids (solutions, suspensions) and oily or staining compounds
Wedgwood- used for grinding dry crystals and hard powders
Porcelain- used to blend powders and pulverize gummy consistencies
What is the Master Formulation Record? - correct Answersrecipe that provides all
ingredients and instructions for preparing a compounded product. includes compound
name, strength, dosage form, all calculations, and everything needed to make the
compound
What is the compounding log? - correct Answersit's the log book of all products made in
the pharmacy
what is a QA plan? - correct Answersquality assurance plan that outlines the steps and
actions that ensure the maintenance of proper standards for compounding preparations.
needs to be reviewed and updated regularly.
ADR of compounded products would be recorded where? - correct AnswersIn the
pharmacy's compounding record
Comminution - correct Answersreduction of solid particles to smaller size by crushing or
grinding
AKA-trituration and levigation
trituration - correct Answersgrinding powders into smaller particles with motor and
pestle
levigation - correct Answerstrituration with liquid to help grinding process.
give an example of a lubricant for non-sterile dry compounding - correct
Answersmagnesium stearate
What is the purpose of a surfactant in regard to dry compounding? Give an example -
correct Answersneutralizes a static charge which keeps the powder from floating away
