Nurs 5334 advanced pharmacology quiz 1 questions and answers
2026-27 updates 100% correct uta.
NURS 5334 Advanced Pharmacology Quiz 1 Practice Questions
180 Multiple Choice Questions with Answers and Rationales
SECTION 1: PHARMACOKINETICS & PHARMACODYNAMICS
FUNDAMENTALS (Questions 1-40)
Question 1
Which of the following best distinguishes pharmacodynamics from
pharmacokinetics?
A) Pharmacodynamics is what the body does to the drug;
pharmacokinetics is what the drug does to the body.
B) Pharmacodynamics is the study of drug absorption and distribution;
pharmacokinetics is the study of drug metabolism and excretion.
C) Pharmacodynamics is what the drug does to the body;
pharmacokinetics is what the body does to the drug.
D) Pharmacodynamics only involves receptor binding; pharmacokinetics
only involves drug movement across membranes.
Correct Answer: C
,Rationale: Pharmacodynamics describes the biochemical and
physiologic effects of drugs and their mechanisms of action—what the
drug does to the body. Pharmacokinetics refers to the processes of
absorption, distribution, metabolism, and excretion (ADME)—what the
body does to the drug. This foundational distinction is essential for
understanding drug action .
Question 2
The four major pharmacokinetic processes are:
A) Absorption, Digestion, Metabolism, and Excretion
B) Administration, Distribution, Metabolism, and Elimination
C) Absorption, Distribution, Metabolism, and Excretion
D) Absorption, Distribution, Metabolism, and Elimination
Correct Answer: C
Rationale: The four major pharmacokinetic processes are Absorption,
Distribution, Metabolism, and Excretion (ADME). These processes
determine the concentration of a drug at its sites of action over time
and help predict onset, peak duration, and elimination. Digestion and
administration are not standard components of the ADME framework .
,Question 3
A drug reaches steady-state concentration in approximately:
A) Two half-lives
B) Three half-lives
C) Four half-lives
D) Five half-lives
Correct Answer: D
Rationale: Steady-state is reached after approximately 4-5 half-lives,
with about 94% of steady state reached after four half-lives and more
than 97% after five half-lives. This principle determines dosing intervals
and the time to therapeutic effect, making it crucial for clinical
prescribing .
Question 4
A patient is prescribed a drug with a half-life of 12 hours. How long will
it take to reach steady-state concentration with regular dosing?
, A) 12 hours
B) 24 hours
C) 48 hours
D) 60 hours
Correct Answer: D
Rationale: Steady-state is reached after approximately 5 half-lives. Five
multiplied by 12 hours equals 60 hours. This calculation is essential for
predicting when a drug will reach its full therapeutic effect and for
planning appropriate monitoring intervals .
Question 5
What is bioavailability?
A) The amount of drug bound to plasma proteins
B) The fraction of an administered dose that reaches systemic
circulation unchanged
C) The time required for drug concentration to decrease by half
2026-27 updates 100% correct uta.
NURS 5334 Advanced Pharmacology Quiz 1 Practice Questions
180 Multiple Choice Questions with Answers and Rationales
SECTION 1: PHARMACOKINETICS & PHARMACODYNAMICS
FUNDAMENTALS (Questions 1-40)
Question 1
Which of the following best distinguishes pharmacodynamics from
pharmacokinetics?
A) Pharmacodynamics is what the body does to the drug;
pharmacokinetics is what the drug does to the body.
B) Pharmacodynamics is the study of drug absorption and distribution;
pharmacokinetics is the study of drug metabolism and excretion.
C) Pharmacodynamics is what the drug does to the body;
pharmacokinetics is what the body does to the drug.
D) Pharmacodynamics only involves receptor binding; pharmacokinetics
only involves drug movement across membranes.
Correct Answer: C
,Rationale: Pharmacodynamics describes the biochemical and
physiologic effects of drugs and their mechanisms of action—what the
drug does to the body. Pharmacokinetics refers to the processes of
absorption, distribution, metabolism, and excretion (ADME)—what the
body does to the drug. This foundational distinction is essential for
understanding drug action .
Question 2
The four major pharmacokinetic processes are:
A) Absorption, Digestion, Metabolism, and Excretion
B) Administration, Distribution, Metabolism, and Elimination
C) Absorption, Distribution, Metabolism, and Excretion
D) Absorption, Distribution, Metabolism, and Elimination
Correct Answer: C
Rationale: The four major pharmacokinetic processes are Absorption,
Distribution, Metabolism, and Excretion (ADME). These processes
determine the concentration of a drug at its sites of action over time
and help predict onset, peak duration, and elimination. Digestion and
administration are not standard components of the ADME framework .
,Question 3
A drug reaches steady-state concentration in approximately:
A) Two half-lives
B) Three half-lives
C) Four half-lives
D) Five half-lives
Correct Answer: D
Rationale: Steady-state is reached after approximately 4-5 half-lives,
with about 94% of steady state reached after four half-lives and more
than 97% after five half-lives. This principle determines dosing intervals
and the time to therapeutic effect, making it crucial for clinical
prescribing .
Question 4
A patient is prescribed a drug with a half-life of 12 hours. How long will
it take to reach steady-state concentration with regular dosing?
, A) 12 hours
B) 24 hours
C) 48 hours
D) 60 hours
Correct Answer: D
Rationale: Steady-state is reached after approximately 5 half-lives. Five
multiplied by 12 hours equals 60 hours. This calculation is essential for
predicting when a drug will reach its full therapeutic effect and for
planning appropriate monitoring intervals .
Question 5
What is bioavailability?
A) The amount of drug bound to plasma proteins
B) The fraction of an administered dose that reaches systemic
circulation unchanged
C) The time required for drug concentration to decrease by half
