Question 1
Charlie is a 65-year-old male who has been diagnosed with hypertension and benign
prostatic hyperplasia. Doxazosin has been chosen to treat his hypertension because it:
1. Increases peripheral vasoconstriction
2. Decreases detrusor muscle contractility
3. Lowers supine blood pressure more than standing pressure
4. Relaxes smooth muscle in the bladder neck
CORRECT ANSWER
4. Relaxes smooth muscle in the bladder neck
Question 2
To reduce potential adverse effects, patients taking a peripherally acting alpha1 antagonist
should do all of the following EXCEPT:
1. Take the dose at bedtime
2. Sit up slowly and dangle their feet before standing
3. Monitor their blood pressure and skip a dose if the pressure is less than 120/80
4. Weigh daily and report weight gain of greater than 2 pounds in one day
CORRECT ANSWER
3. Monitor their blood pressure and skip a dose if the pressure is less than 120/80
Question 3
1
@THE STUDY VAULT
,John has clonidine, a centrally acting adrenergic blocker, prescribed for his hypertension.
He should:
1. Not miss a dose or stop taking the drug because of potential rebound hypertension
2. Increase fiber in the diet to treat any diarrhea that may occur
3. Reduce fluid intake to less than 2 liters per day to prevent fluid retention
4. Avoid sitting for long periods, as this can lead to deep vein thrombosis
CORRECT ANSWER
1. Not miss a dose or stop taking the drug because of potential rebound hypertension
Question 4
Clonidine has several off-label uses, including:
1. Alcohol and nicotine withdrawal
2. Post-herpetic neuralgia
3. Both 1 and 2
4. Neither 1 nor 2
CORRECT ANSWER
3. Both 1 and 2
Question 5
Jim is being treated for hypertension. Because he has a history of heart attack, the drug
chosen is atenolol. Beta blockers treat hypertension by:
1. Increasing heart rate to improve cardiac output
2. Reducing vascular smooth muscle tone
3. Increasing aldosterone-mediated volume activity
4. Reducing aqueous humor production
2
@THE STUDY VAULT
,CORRECT ANSWER
2. Reducing vascular smooth muscle tone
Question 6
Which of the following adverse effects are less likely in a beta 1-selective blocker?
1. Dysrhythmias
2. Impaired insulin release
3. Reflex orthostatic changes
4. Decreased triglycerides and cholesterol
CORRECT ANSWER
2. Impaired insulin release
Question 7
Richard is 70 years old and has a history of cardiac dysrhythmias. He has been prescribed
nadolol. You do his annual laboratory work and find a CrCl of 25 ml/min. What action
should you take related to his nadolol?
1. Extend the dosage interval.
2. Decrease the dose by 75%.
3. Take no action because this value is expected in the older adult.
4. Schedule a serum creatinine level to validate the CrCl value.
CORRECT ANSWER
1. Extend the dosage interval.
Question 8
Beta blockers are the drugs of choice for exertional angina because they:
3
@THE STUDY VAULT
, 1. Improve myocardial oxygen supply by vasodilating the coronary arteries
2. Decrease myocardial oxygen demand by decreasing heart rate and vascular resistance
3. Both 1 and 2
4. Neither 1 nor 2
CORRECT ANSWER
2. Decrease myocardial oxygen demand by decreasing heart rate and vascular resistance
Question 9
Adherence to beta blocker therapy may be affected by their:
1. Short half-lives requiring twice daily dosing
2. Tendency to elevate lipid levels
3. Effects on the male genitalia, which may produce impotence
4. None of the above
CORRECT ANSWER
3. Effects on the male genitalia, which may produce impotence
Question 10
Beta blockers have favorable effects on survival and disease progression in heart failure.
Treatment should be initiated when the:
1. Symptoms are severe
2. Patient has not responded to other therapies
3. Patient has concurrent hypertension
4. Left ventricular dysfunction is diagnosed
CORRECT ANSWER
4. Left ventricular dysfunction is diagnosed
4
@THE STUDY VAULT
Charlie is a 65-year-old male who has been diagnosed with hypertension and benign
prostatic hyperplasia. Doxazosin has been chosen to treat his hypertension because it:
1. Increases peripheral vasoconstriction
2. Decreases detrusor muscle contractility
3. Lowers supine blood pressure more than standing pressure
4. Relaxes smooth muscle in the bladder neck
CORRECT ANSWER
4. Relaxes smooth muscle in the bladder neck
Question 2
To reduce potential adverse effects, patients taking a peripherally acting alpha1 antagonist
should do all of the following EXCEPT:
1. Take the dose at bedtime
2. Sit up slowly and dangle their feet before standing
3. Monitor their blood pressure and skip a dose if the pressure is less than 120/80
4. Weigh daily and report weight gain of greater than 2 pounds in one day
CORRECT ANSWER
3. Monitor their blood pressure and skip a dose if the pressure is less than 120/80
Question 3
1
@THE STUDY VAULT
,John has clonidine, a centrally acting adrenergic blocker, prescribed for his hypertension.
He should:
1. Not miss a dose or stop taking the drug because of potential rebound hypertension
2. Increase fiber in the diet to treat any diarrhea that may occur
3. Reduce fluid intake to less than 2 liters per day to prevent fluid retention
4. Avoid sitting for long periods, as this can lead to deep vein thrombosis
CORRECT ANSWER
1. Not miss a dose or stop taking the drug because of potential rebound hypertension
Question 4
Clonidine has several off-label uses, including:
1. Alcohol and nicotine withdrawal
2. Post-herpetic neuralgia
3. Both 1 and 2
4. Neither 1 nor 2
CORRECT ANSWER
3. Both 1 and 2
Question 5
Jim is being treated for hypertension. Because he has a history of heart attack, the drug
chosen is atenolol. Beta blockers treat hypertension by:
1. Increasing heart rate to improve cardiac output
2. Reducing vascular smooth muscle tone
3. Increasing aldosterone-mediated volume activity
4. Reducing aqueous humor production
2
@THE STUDY VAULT
,CORRECT ANSWER
2. Reducing vascular smooth muscle tone
Question 6
Which of the following adverse effects are less likely in a beta 1-selective blocker?
1. Dysrhythmias
2. Impaired insulin release
3. Reflex orthostatic changes
4. Decreased triglycerides and cholesterol
CORRECT ANSWER
2. Impaired insulin release
Question 7
Richard is 70 years old and has a history of cardiac dysrhythmias. He has been prescribed
nadolol. You do his annual laboratory work and find a CrCl of 25 ml/min. What action
should you take related to his nadolol?
1. Extend the dosage interval.
2. Decrease the dose by 75%.
3. Take no action because this value is expected in the older adult.
4. Schedule a serum creatinine level to validate the CrCl value.
CORRECT ANSWER
1. Extend the dosage interval.
Question 8
Beta blockers are the drugs of choice for exertional angina because they:
3
@THE STUDY VAULT
, 1. Improve myocardial oxygen supply by vasodilating the coronary arteries
2. Decrease myocardial oxygen demand by decreasing heart rate and vascular resistance
3. Both 1 and 2
4. Neither 1 nor 2
CORRECT ANSWER
2. Decrease myocardial oxygen demand by decreasing heart rate and vascular resistance
Question 9
Adherence to beta blocker therapy may be affected by their:
1. Short half-lives requiring twice daily dosing
2. Tendency to elevate lipid levels
3. Effects on the male genitalia, which may produce impotence
4. None of the above
CORRECT ANSWER
3. Effects on the male genitalia, which may produce impotence
Question 10
Beta blockers have favorable effects on survival and disease progression in heart failure.
Treatment should be initiated when the:
1. Symptoms are severe
2. Patient has not responded to other therapies
3. Patient has concurrent hypertension
4. Left ventricular dysfunction is diagnosed
CORRECT ANSWER
4. Left ventricular dysfunction is diagnosed
4
@THE STUDY VAULT
