??
??
??
47
s2
iu
en
yg
ud
, Huether & McCance — Understanding Pathophysiology, 7e
Contents
Understanding Pathophysiology
7th Edition · Sue E. Huether & Kathryn L. McCance
tu
PART ONE — BASIC CONCEPTS OF PATHOPHYSIOLOGY
Unit 1: The Cell
1. Cellular Biology
d
2. Genes and Genetic Diseases
3. Epigenetics and Disease
yg
4. Altered Cellular and Tissue Biology
5. Fluids and Electrolytes, Acids and Bases
Unit 2: Mechanisms of Self-Defense
6. Innate Immunity: Inflammation and Wound Healing
en
7. Adaptive Immunity
8. Alterations in Immunity
9. Infection and Defects in Mechanisms of Defense
10. Stress and Disease
iu
Unit 3: Cellular Proliferation: Cancer
11. Biology of Cancer
12. Cancer Epidemiology
s2
13. Cancer in Children and Adolescents
PART TWO — BODY SYSTEMS AND DISEASES
Unit 4: The Neurologic System
47
14. Structure and Function of the Neurologic System
15. Pain, Temperature, Sleep, and Sensory Function
16. Alterations in Cognitive Systems, Cerebral Hemodynamics, and Motor Function
17. Disorders of the Central and Peripheral Nervous Systems and Neuromuscular Junction
??
18. Alterations of Neurologic Function in Children
Unit 5: The Endocrine System
19. Mechanisms of Hormonal Regulation
??
20. Alterations of Hormonal Regulation
21. Obesity and Disorders of Nutrition
Unit 6: The Hematologic System
??
22. Structure and Function of the Hematologic System
23. Alterations of Hematologic Function
24. Alterations of Hematologic Function in Children
Unit 7: The Cardiovascular and Lymphatic Systems
??
25. Structure and Function of the Cardiovascular and Lymphatic Systems
26. Alterations of Cardiovascular Function
27. Alterations of Cardiovascular Function in Children
Unit 8: The Pulmonary System
1
, Huether & McCance — Understanding Pathophysiology, 7e
28. Structure and Function of the Pulmonary System
29. Alterations of Pulmonary Function
30. Alterations of Pulmonary Function in Children
Unit 9: The Renal and Urologic Systems
31. Structure and Function of the Renal and Urologic Systems
tu
32. Alterations of Renal and Urinary Tract Function
33. Alterations of Renal and Urinary Tract Function in Children
Unit 10: The Reproductive Systems
34. Structure and Function of the Reproductive Systems
d
35. Alterations of the Female Reproductive System
36. Alterations of the Male Reproductive System
yg
Unit 11: The Digestive System
37. Structure and Function of the Digestive System
38. Alterations of Digestive Function
en
39. Alterations of Digestive Function in Children
Unit 12: The Musculoskeletal and Integumentary Systems
40. Structure and Function of the Musculoskeletal System
41. Alterations of Musculoskeletal Function
iu
42. Alterations of Musculoskeletal Function in Children
43. Structure, Function, and Disorders of the Integument
44. Alterations of the Integument in Children
s2
47
??
??
??
??
2
,Chapter 1
MULTIPLE CHOICE
1. A student is observing a cell under the microscope. It is observed to have supercoiled DNA
with histones. Which of the following would also be observed by the student?
a. A single circular chromosome
b. A nucleus
c. Free-floating nuclear material
d. No organelles
ud
ANS: B
The cell described is a eukaryotic cell, so it has histones and a supercoiled DNA within its
nucleus; thus, the nucleus should be observed. A single circular chromosome called a
prokaryote contains free-floating nuclear material but has no organelles.
yg
2. A nurse is instructing the staff about cellular functions. Which cellular function is the nurse
describing when an isolated cell absorbs oxygen and uses it to transform nutrients to energy?
a. Metabolic absorption
b. Communication
en
c. Secretion
d. Respiration
ANS: D
The cell’s ability to absorb oxygen is referred to as respiration while its communication ability
involves maintenance of a steadyN dynamic state, metabolic absorption provides nutrition, and
iu
secretion allows for the synthesizing of new substances.
3. A eukaryotic cell is undergoing DNA replication. In which region of the cell would most of
s2
the genetic information be contained?
a. Mitochondria
b. Ribosome
c. Nucleolus
d. Nucleus cytoplasm
47
ANS: C
The region of the cell that contains genetic material, including a large amount of ribonucleic
acid, most of the DNA, and DNA-binding proteins, is the nucleolus, which is located within
the cell’s nucleus. Mitochondria is associated with cellular respiration while ribosomes are
??
involved with protein manufacturing. Cytoplasm is a fluid filling that is a component of the
cell.
4. Which of the following can remove proteins attached to the cell’s bilayer by dissolving the
??
layer itself?
a. Peripheral membrane proteins
b. Integral membrane proteins
c. Glycoproteins
?
d. Cell adhesion molecules