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TEST BANK: RN PHARMACOLOGY EXAM 2 | 400 Questions & Answers | A-Grade Practice Test | 2026–2027

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Prepare for RN Pharmacology with this comprehensive 400-question Exam 2 practice resource for 2026–2027. It covers medication administration, drug classifications, adverse effects, interactions, patient teaching, safety precautions, monitoring, emergency medications, and priority nursing interventions. Each question includes a clearly highlighted answer and a concise rationale to reinforce key pharmacology concepts and support effective exam preparation.

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TEST BANK: RN PHARMACOLOGY EXAM 2 | 400
Questions & Answers | A-Grade Practice Test | 2026–
2027




RN Pharmacology Exam 2 • 2026–2027 • Page 1

, TABLE OF CONTENTS


1. Medication Safety & Administration — Questions 1–40
2. Cardiovascular Medications — Questions 41–80
3. Endocrine & Diabetes — Questions 81–120
4. Antimicrobials — Questions 121–160
5. Pain, Sedation & Neurologic Medications — Questions 161–200
6. Respiratory Medications — Questions 201–240
7. Gastrointestinal Medications — Questions 241–280
8. Psychiatric Medications — Questions 281–320
9. Emergency & Antidote Review — Questions 321–360
10. Comprehensive Mixed Review — Questions 361–400




RN Pharmacology Exam 2 • 2026–2027 • Page 2

,1. A client taking warfarin has an INR of 5.8 without bleeding. Which action is most appropriate?
A. Hold the next warfarin dose and notify the provider.
B. Give an additional dose of warfarin.
C. Administer aspirin.
D. Encourage foods high in vitamin K immediately.
ANSWER: A
Rationale: An elevated INR increases bleeding risk. The prescribed response depends on severity and bleeding status; a
markedly elevated INR warrants holding therapy and contacting the provider.

2. The nurse is reviewing a client's medication plan. A client taking warfarin has an INR of 5.8
withoutbleeding. Which action is most appropriate?
A. Hold the next warfarin dose and notify the provider.
B. Give an additional dose of warfarin.
C. Administer aspirin.
D. Encourage foods high in vitamin K immediately.
ANSWER: A
Rationale: An elevated INR increases bleeding risk. The prescribed response depends on severity and bleeding status; a
markedly elevated INR warrants holding therapy and contacting the provider.

3. During medication administration, the nurse notes the following situation. A client taking warfarin hasan
INR of 5.8 without bleeding. Which action is most appropriate?
A. Hold the next warfarin dose and notify the provider.
B. Give an additional dose of warfarin.
C. Administer aspirin.
D. Encourage foods high in vitamin K immediately.
ANSWER: A
Rationale: An elevated INR increases bleeding risk. The prescribed response depends on severity and bleeding status; a
markedly elevated INR warrants holding therapy and contacting the provider.

4. A nursing student asks about the safest action in this situation. A client taking warfarin has an INR of
5.8 without bleeding. Which action is most appropriate?
A. Hold the next warfarin dose and notify the provider.
B. Give an additional dose of warfarin.
C. Administer aspirin.
D. Encourage foods high in vitamin K immediately.
ANSWER: A
Rationale: An elevated INR increases bleeding risk. The prescribed response depends on severity and bleeding status; a
markedly elevated INR warrants holding therapy and contacting the provider.

5. Which assessment finding is most concerning after administering IV morphine?
A. Respiratory rate of 8/min
B. Mild nausea
C. Dry mouth
D. Pain rated 4/10
ANSWER: A




RN Pharmacology Exam 2 • 2026–2027 • Page 3

, Rationale: Opioids can cause life-threatening respiratory depression. A markedly decreased respiratory rate requires immediate
assessment and intervention.

6. The nurse is reviewing a client's medication plan. Which assessment finding is most concerning
afteradministering IV morphine?
A. Respiratory rate of 8/min
B. Mild nausea
C. Dry mouth
D. Pain rated 4/10
ANSWER: A
Rationale: Opioids can cause life-threatening respiratory depression. A markedly decreased respiratory rate requires immediate
assessment and intervention.

7. During medication administration, the nurse notes the following situation. Which assessment finding
ismost concerning after administering IV morphine?
A. Respiratory rate of 8/min
B. Mild nausea
C. Dry mouth
D. Pain rated 4/10
ANSWER: A
Rationale: Opioids can cause life-threatening respiratory depression. A markedly decreased respiratory rate requires immediate
assessment and intervention.

8. A nursing student asks about the safest action in this situation. Which assessment finding is
mostconcerning after administering IV morphine?
A. Respiratory rate of 8/min
B. Mild nausea
C. Dry mouth
D. Pain rated 4/10
ANSWER: A
Rationale: Opioids can cause life-threatening respiratory depression. A markedly decreased respiratory rate requires immediate
assessment and intervention.

9. A client receiving vancomycin reports ringing in the ears. What should the nurse do?
A. Hold the medication and notify the provider.
B. Administer the next dose early.
C. Reassure the client that this is expected.
D. Give an antacid.
ANSWER: A
Rationale: Ototoxicity is a serious potential adverse effect of vancomycin and warrants prompt evaluation.

10. The nurse is reviewing a client's medication plan. A client receiving vancomycin reports ringing in
theears. What should the nurse do?
A. Hold the medication and notify the provider.
B. Administer the next dose early.
C. Reassure the client that this is expected.



RN Pharmacology Exam 2 • 2026–2027 • Page 4

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