W E S T E R N G O V E R N O R S U N I V E R S I T Y · C O L L E G E O F H E A LT H P R O F E S S I O N S
WGU D236
Homeostasis &
Pathophysiology
Practice Question Bank — Fluid Balance, Genetics & Immunity
Course: Pathophysiology
Edition 1 · September 2026
Table of Contents
1. Instructions for Use 2
2. Practice Questions with Answers & Rationales 2
WGU D236 · Western Governors University Page 1
,WGU D236 HOMEOSTASIS PRACTICE GUIDE INSTRUCTIONS & PRACTICE QUESTIONS
How to Use This Guide
This review contains 44 practice questions covering key concepts from WGU D236:
Homeostasis. Each question includes four answer choices, a clearly marked correct answer, and
a detailed clinical rationale explaining the underlying pathophysiology.
Category: Fluids, Genetics, Immunity & Acid-Base
1 Intercellular fluids make up what proportion of bodily fluids?
A 1/3
B 2/3
C 1/2
D 3/4
Why B is correct: Intercellular fluids (intracellular fluid) make up approximately 2/3 of the
body's total water, primarily within muscle cells.
A — This is the proportion of extracellular fluid.
C — This is incorrect.
D — This is incorrect.
, 2 Extracellular fluids are found in which of the following?
A Inside muscle cells
B Blood vessels, skin tissues, and cerebrospinal fluid (CSF)
C Within the nucleus of cells
D Exclusively in the lymphatic system
Why B is correct: Extracellular fluid is found in blood vessels (plasma), interstitial fluid (skin
tissues), and cerebrospinal fluid.
A — This describes intracellular fluid.
C — This is incorrect.
D — This is only a partial representation.
3 Diffusion is best defined as:
A Movement of solutes from an area of greater concentration to lesser concentration
B Movement of fluid from lower to higher solute concentration
C Movement of water due to hydrostatic pressure
D Active transport against a concentration gradient
Why A is correct: Diffusion is the passive movement of solutes from an area of greater
concentration to lesser concentration, leading to equalization.
B — This describes osmosis.
C — This describes filtration.
D — This is active transport.
WGU D236
Homeostasis &
Pathophysiology
Practice Question Bank — Fluid Balance, Genetics & Immunity
Course: Pathophysiology
Edition 1 · September 2026
Table of Contents
1. Instructions for Use 2
2. Practice Questions with Answers & Rationales 2
WGU D236 · Western Governors University Page 1
,WGU D236 HOMEOSTASIS PRACTICE GUIDE INSTRUCTIONS & PRACTICE QUESTIONS
How to Use This Guide
This review contains 44 practice questions covering key concepts from WGU D236:
Homeostasis. Each question includes four answer choices, a clearly marked correct answer, and
a detailed clinical rationale explaining the underlying pathophysiology.
Category: Fluids, Genetics, Immunity & Acid-Base
1 Intercellular fluids make up what proportion of bodily fluids?
A 1/3
B 2/3
C 1/2
D 3/4
Why B is correct: Intercellular fluids (intracellular fluid) make up approximately 2/3 of the
body's total water, primarily within muscle cells.
A — This is the proportion of extracellular fluid.
C — This is incorrect.
D — This is incorrect.
, 2 Extracellular fluids are found in which of the following?
A Inside muscle cells
B Blood vessels, skin tissues, and cerebrospinal fluid (CSF)
C Within the nucleus of cells
D Exclusively in the lymphatic system
Why B is correct: Extracellular fluid is found in blood vessels (plasma), interstitial fluid (skin
tissues), and cerebrospinal fluid.
A — This describes intracellular fluid.
C — This is incorrect.
D — This is only a partial representation.
3 Diffusion is best defined as:
A Movement of solutes from an area of greater concentration to lesser concentration
B Movement of fluid from lower to higher solute concentration
C Movement of water due to hydrostatic pressure
D Active transport against a concentration gradient
Why A is correct: Diffusion is the passive movement of solutes from an area of greater
concentration to lesser concentration, leading to equalization.
B — This describes osmosis.
C — This describes filtration.
D — This is active transport.
