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HESI COMPASS Comprehensive Exit Exam Questions & Answers Updated 2026/2027 – Nursing NCLEX RN Study Guide – Instant Download

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Prepare for the **HESI COMPASS Comprehensive Exit Exam** with this comprehensive nursing exam-preparation resource featuring questions, answers, rationales, clinical scenarios, medication concepts, maternity nursing, psychiatric nursing, medical-surgical nursing, pediatric nursing, renal nursing, cardiovascular care, oncology, and dosage calculations. This resource is designed for nursing students preparing for a comprehensive HESI exit examination, nursing school exit testing, NCLEX-RN preparation, and final nursing course review. The material covers a broad range of nursing concepts and scenario-based questions designed to reinforce clinical judgment, prioritization, assessment, pharmacology, patient safety, and evidence-based nursing interventions. ### COMPREHENSIVE TOPICS COVERED **Fundamentals of Nursing** * Nursing assessment and prioritization * Patient safety * Medication administration * Vital signs * Intake and output * Fluid balance * NPO precautions * Preoperative and postoperative care * Therapeutic communication * Client education * Nursing interventions * Clinical decision-making **Pharmacology & Medication Administration** * Enalapril maleate * ACE inhibitors * Postural hypotension * Ibuprofen * Lorazepam IV administration * Phenelzine * MAOI precautions * Risperidone * Antipsychotic medications * Tardive dyskinesia * Lithium carbonate * Lithium toxicity * Carbidopa/levodopa * Neostigmine * Amantadine * Chlorpromazine * Reteplase * Cisplatin * Oxytocin * Terbutaline * Magnesium sulfate * Calcium gluconate * Ferrous sulfate **Medical-Surgical Nursing** * Cardiovascular disorders * Acute myocardial infarction * Premature ventricular contractions * CABG postoperative care * Respiratory disorders * COPD * Carbon monoxide poisoning * Silicosis * Sarcoidosis * Pleural effusion * Empyema * Thoracentesis * Chronic renal failure * End-stage renal disease * Hemodialysis * Ileostomy * Dehydration * Electrolyte and fluid restrictions * Parkinson's disease * Myasthenia gravis * Huntington's disease * Rheumatoid arthritis * Systemic lupus erythematosus * Gout * Osteoporosis **Psychiatric & Mental Health Nursing** * Depression * Anxiety * Powerlessness * Ineffective coping * Agoraphobia * Systematic desensitization * Electroconvulsive therapy * Antidepressant medications * MAOI dietary restrictions * Antipsychotic medications * Tardive dyskinesia * Therapeutic communication * Suicide risk and safety considerations * Psychotropic medication monitoring **Maternity & Obstetric Nursing** * Pregnancy assessment * High-risk pregnancy * Preeclampsia * Magnesium sulfate * Calcium gluconate * Placenta previa * Placental separation * Placental abruption considerations * Labor and delivery * Fetal heart rate monitoring * Amniocentesis * Fetal lung maturity * Sickle-cell disease in pregnancy * Gestational nutrition * Folic acid * Postpartum assessment * Uterine inversion * Postpartum hemorrhage considerations * Oxytocin administration * Uterine hypertonicity * Postpartum fundal assessment * DIC * Pregnancy complications **Pediatric Nursing** * Type 1 diabetes mellitus * Exercise and diabetes management * Carbohydrate intake * Scoliosis * TLSO brace * Pediatric patient education * Growth and development considerations **Women's Health & Oncology** * Breast cancer * Infiltrating ductal carcinoma * Peau d'orange * Mastectomy * Sexual adjustment * Cervical cancer * Cisplatin chemotherapy * Radical vulvectomy * Postoperative gynecologic care * Skin cancer prevention **Renal Nursing** * Chronic renal failure * Hemodialysis * Oliguria * Fluid restriction * Sodium restriction * Potassium restriction * Dialysis nutrition * Renal diet * Dehydration * Ileostomy-related fluid loss * Intake and output calculations **Dosage Calculation & Clinical Mathematics** * Medication dosage calculations * IV medication calculations * Morphine dosage * Milliliter calculations * Fluid intake calculations * 24-hour intake and output * IV solution volumes * Clinical dosage problems **Gastrointestinal Nursing** * Upper GI series * Barium studies * NPO preparation * Barium elimination * Constipation prevention * Esophagogastroduodenoscopy * Gag reflex assessment * Gastrointestinal diagnostic procedures ### HIGH-VALUE EXAM PREPARATION AREAS The material emphasizes the types of concepts commonly encountered in comprehensive nursing examinations, including **priority nursing actions, medication administration, adverse effects, patient teaching, clinical assessment, laboratory interpretation, maternity emergencies, psychiatric care, renal disorders, cardiovascular emergencies, oncology, pediatric care, and dosage calculations**. Questions include multiple-choice, select-all-that-apply, and calculation-style formats. Rationales and answer explanations are included with the supplied material to support review and help learners understand the reasoning behind the selected responses. ### USEFUL FOR * HESI Comprehensive Exit Exam preparation * HESI COMPASS exam review * Nursing school exit exam preparation * RN comprehensive exam review * NCLEX-RN preparation * Nursing fundamentals review * Medical-surgical nursing review * Maternal-newborn nursing review * Pediatric nursing review * Psychiatric nursing review * Pharmacology review * Dosage calculation review * Nursing clinical judgment preparation * Final nursing course examination review **Important:** This is an independent study resource based on the material provided. It is not an official HESI, Elsevier, or nursing-school publication and does not guarantee a particular examination result.

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Nightingale College BSN 266


HESI COMPASS COMPREHENSIVE EXIT EXAM
2025/2026 AND PRACTICE EXAM TEST BANK WITH
A STUDY GUIDE | ALL VERSIONS OF THE EXAM
WITH ALL MODULES COVERED |
ACCURATE AND VERIFIED QUESTIONS AND
ANSWERS FOR GUARANTEED PASS | LATEST
UPDATE
C




1-Enalapril maleate (Vasotec) is prescribed for a A. Checking the client's blood pressure
hospitalized client. Which assessment does the
nurse perform as a priority before administering Checking the client's blood pressure
the medication? Enalapril maleate is an angiotensin-converting enzyme (ACE) inhibitor
used to treat hypertension. One common side effect is postural
A. Checking the client's blood pressure hypotension. Therefore the nurse would check the client's blood
B.Checking the client's peripheral pulses pressure immediately before administering each dose. Checking the
C. Checking the most recent potassium level client's peripheral pulses, the results of the most recent potassium level,
D.Checking the client's intake-and-output record and the intake and output for the previous 24 hours are not specifically
for the last 24 hours associated with this mediation.

,2-A client is scheduled to undergo an upper C. "I need to drink citrate of magnesia the night before the test and
gastrointestinal (GI) series, and the nurse provides give myself a Fleet enema on the morning of the test."
instructions to the client about the test. Which
statement by the client indicates a need for further An upper GI series involves visualization of the esophagus, duodenum,
instruction? and upper jejunum by means of the use of a contrast medium. It
involves swallowing a contrast medium (usually barium), which is
A. "The test will take about 30 minutes." administered in a flavored milkshake. Films are taken at intervals during
B. "I need to fast for 8 hours before the test." the test, which takes about 30 minutes. No special preparation is
C. "I need to drink citrate of magnesia the night necessary before a GI series, except that NPO status must be
before the test and give myself a Fleet enema on maintained for 8 hours before the test. After an upper GI series, the
the morning of the test." client is prescribed a laxative to hasten elimination of the barium.
D. "I need to take a laxative after the test is Barium that remains in the colon may become hard and difficult to
completed, because the liquid that I'll have to expel, leading to fecal impaction.
drink for the test can be constipating."



3-A nurse on the evening shift checks a physician's B. Ask the answering service to contact the on-call physician
prescriptions and notes that the dose of a
prescribed medication is higher than the normal
dose. The nurse calls the physician's answering
service and is told that the physician is off for the
night and will be available in the morning. The
nurse should:


A. Call the nursing supervisor
B. Ask the answering service to contact the on-call
physician
C. Withhold the medication until the physician
can be reached in the morning
D. Administer the medication but consult the
physician when he becomes available



4.An emergency department (ED) nurse is B. Asking the ED physician to check the client
monitoring a client with suspected acute
myocardial infarction (MI) who is awaiting transfer
to the coronary intensive care unit. The nurse notes
the sudden onset of premature ventricular
contractions (PVCs) on the monitor, checks
the client's carotid pulse, and determines that
the PVCs are not resulting in perfusion. The
appropriate action by the nurse is:


A. Documenting the findings
B. Asking the ED physician to check the client
C. Continuing to monitor the client's cardiac status
D. Informing the client that PVCs are expected
after an MI

, 5. NPO status is imposed 8 hours A. Administer the antihypertensive with a small sip of water
before the procedure on a client scheduled
to undergo
electroconvulsive therapy (ECT) at 1 p.m. On the
morning of the procedure, the nurse checks the
client's record and notes that the client routinely
takes an oral antihypertensive medication each
morning. The nurse should:


A. Administer the antihypertensive with a small
sip of water
B.Withhold the antihypertensive and administer it
at bedtime
C. Administer the medication by way of
the intravenous (IV) route
D.Hold the antihypertensive and resume
its administration on the day after the
ECT


6 A client who recently underwent coronary artery
A. "Tell me more about what you're feeling."
bypass graft surgery comes to the physician's
office for a follow-up visit. On assessment, the
client tells the nurse that he is feeling
depressed. Which response by the nurse is
therapeutic?


A. "Tell me more about what you're feeling."
B."That's a normal response after this type
of surgery."
C. "It will take time, but, I promise you, you will get
over this depression."
D."Every client who has this surgery feels the
same way for about a month."


7 A client in labor experiences spontaneous
A. Contacting the physician Correct
rupture of the membranes. The nurse immediately
counts the fetal heart rate (FHR) for 1 full minute
and then checks the amniotic fluid. The nurse
notes that the fluid is yellow and has a strong
odor.
Which of the following actions should be the
nurse's priority?


A. Contacting the physician
B. Documenting the findings
C. Checking the fluid for protein
D. Continuing to monitor the client and the FHR


8 A nurse has assisted a physician in inserting a
A. Call the radiography department to obtain a chest x-ray
central venous access device into a client with
a diagnosis of severe malnutrition who will
be
receiving parenteral nutrition (PN). After insertion
of the catheter, the nurse immediately plans
to:


A. Call the radiography department to obtain a
chest x-ray
B.Check the client's blood glucose level to
serve as a baseline measurement
C. Hang the prescribed bag of PN and start the
infusion at the prescribed rate
D.Infuse normal saline solution through the
catheter at a rate of 100 mL/hr to maintain patency

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