NUR 325 EXAM 1 UPDATED ACTUAL QUESTIONS AND
CORRECT ANSWERS
Question:
1. Brand Name drug
Answer:
Drugs commercial name Capitalized
Question:
2. Generic Drug Name
Answer:
The name given by the company who developed the drug Not capitalized
Question:
3. Forms of oral medications
Answer:
Liquid Powder Capsule Tablet
Question:
4. Fastest to slowest absorption ORAL MEDS
Answer:
Liquid Suspension Powder Capsule Tablet Coated tablet Enteric Coated tablet
Question:
5. Factors affecting absorption
Answer:
-solubility
-drug formulation
-Route of administration
-Form of medication
-Water soluble?
-Good circulation?
-Drug/Food interactions
-First pass effect
-metabolic rate
Question:
6. Parenteral routes of administration
Answer:
IV- fastest Sub-Q IM
Question:
7. Absorption
Answer:
movement of drug from site of administration to various tissues of the body.
,Question:
8. First Pass Effect
Answer:
Part of the drug may deactivate when it passes through the liver to the actual amount going into circulation
(Bioavailability) can be less than what was initially ingested
Question:
9. distribution
Answer:
movement of the drug by circulatory system (after the drug has been absorbed into the bloodstream) to the
intended site of action. Areas with richest blood supply (ex. Liver, Kidneys, Heart) receive the highest
level of the drug. Areas with not as rich supply of blood (ex. bones) and areas with natural barriers (ex.
Blood-brain barrier) receive the least amount of the drug.
Question:
10. Metabolism
Answer:
the change that occurs in a drug into a more or less potent form of the drug, more soluble form of the drug,
or an inactive form of the drug. Liver is responsible for most break down of drugs that occurs in the body.
Question:
11. Drug Half-Life
Answer:
the time it takes for a drug that enters the body to decrease in amount by half. This decrease reflects how
quickly and efficiently a drug metabolizes and excretes. Will affect how often drugs are being
administered (especially if pt has impaired functioning of kidneys and/or liver).
Question:
12. What must be considered about drug levels in the body if a patient has decreased liver and/or kidney
function?
Answer:
-Half life may take longer to reach
-Higher risk for cumulative effect & drug toxicity
-Impaired metabolism of drugs
Question:
13. Onset
Answer:
Amount of time it takes for the drug to demonstrate a therapeutic response.
Question:
14. Peak
Answer:
the time it takes the drug to demonstrate its full therapeutic effect.
Question:
15. Duration
, Answer:
the length of time the drug's therapeutic effect lasts, without additional doses.
Question:
16. Peak Level
Answer:
the point in time when the drug is at its highest level in the body
-Important to know when creating drug schedule for pts
-May be different for pts w/ impaired metabolic functioning
Question:
17. Trough Level
Answer:
the point in time when the drug is at its lowest level in the body
-Important to know when creating drug schedule for pts
-May be different for pts w/ impaired metabolic functioning
Question:
18. Pharmacokinetics
Answer:
describes the absorption, distribution, metabolism, and excretion of drugs.
Question:
19. Pharmacodynamics
Answer:
the biochemical changes that occur in the body as a result of taking the drug. Effects occur secondary to
changes in how cells function, the cellular environment, or actions of enzymes in the body.
Question:
20. adverse drug reaction
Answer:
unintended effects of the drug
Question:
21. therapeutic effects
Answer:
intended effects of the drug
Question:
22. off-label use
Answer:
prescription of drugs for uses other than those specified in the FDA approval
Question:
23. Describe the most severe type of adverse drug reaction and how the patient could present in this case
(clinical manifestations)
CORRECT ANSWERS
Question:
1. Brand Name drug
Answer:
Drugs commercial name Capitalized
Question:
2. Generic Drug Name
Answer:
The name given by the company who developed the drug Not capitalized
Question:
3. Forms of oral medications
Answer:
Liquid Powder Capsule Tablet
Question:
4. Fastest to slowest absorption ORAL MEDS
Answer:
Liquid Suspension Powder Capsule Tablet Coated tablet Enteric Coated tablet
Question:
5. Factors affecting absorption
Answer:
-solubility
-drug formulation
-Route of administration
-Form of medication
-Water soluble?
-Good circulation?
-Drug/Food interactions
-First pass effect
-metabolic rate
Question:
6. Parenteral routes of administration
Answer:
IV- fastest Sub-Q IM
Question:
7. Absorption
Answer:
movement of drug from site of administration to various tissues of the body.
,Question:
8. First Pass Effect
Answer:
Part of the drug may deactivate when it passes through the liver to the actual amount going into circulation
(Bioavailability) can be less than what was initially ingested
Question:
9. distribution
Answer:
movement of the drug by circulatory system (after the drug has been absorbed into the bloodstream) to the
intended site of action. Areas with richest blood supply (ex. Liver, Kidneys, Heart) receive the highest
level of the drug. Areas with not as rich supply of blood (ex. bones) and areas with natural barriers (ex.
Blood-brain barrier) receive the least amount of the drug.
Question:
10. Metabolism
Answer:
the change that occurs in a drug into a more or less potent form of the drug, more soluble form of the drug,
or an inactive form of the drug. Liver is responsible for most break down of drugs that occurs in the body.
Question:
11. Drug Half-Life
Answer:
the time it takes for a drug that enters the body to decrease in amount by half. This decrease reflects how
quickly and efficiently a drug metabolizes and excretes. Will affect how often drugs are being
administered (especially if pt has impaired functioning of kidneys and/or liver).
Question:
12. What must be considered about drug levels in the body if a patient has decreased liver and/or kidney
function?
Answer:
-Half life may take longer to reach
-Higher risk for cumulative effect & drug toxicity
-Impaired metabolism of drugs
Question:
13. Onset
Answer:
Amount of time it takes for the drug to demonstrate a therapeutic response.
Question:
14. Peak
Answer:
the time it takes the drug to demonstrate its full therapeutic effect.
Question:
15. Duration
, Answer:
the length of time the drug's therapeutic effect lasts, without additional doses.
Question:
16. Peak Level
Answer:
the point in time when the drug is at its highest level in the body
-Important to know when creating drug schedule for pts
-May be different for pts w/ impaired metabolic functioning
Question:
17. Trough Level
Answer:
the point in time when the drug is at its lowest level in the body
-Important to know when creating drug schedule for pts
-May be different for pts w/ impaired metabolic functioning
Question:
18. Pharmacokinetics
Answer:
describes the absorption, distribution, metabolism, and excretion of drugs.
Question:
19. Pharmacodynamics
Answer:
the biochemical changes that occur in the body as a result of taking the drug. Effects occur secondary to
changes in how cells function, the cellular environment, or actions of enzymes in the body.
Question:
20. adverse drug reaction
Answer:
unintended effects of the drug
Question:
21. therapeutic effects
Answer:
intended effects of the drug
Question:
22. off-label use
Answer:
prescription of drugs for uses other than those specified in the FDA approval
Question:
23. Describe the most severe type of adverse drug reaction and how the patient could present in this case
(clinical manifestations)