BIOM*3090 FINAL EXAM DRUG LIST UPDATED
ACTUAL QUESTIONS AND CORRECT ANSWERS
Question:
1. Clonidine
Answer:
Sympatholytic - inhibits SNS activity
Centrally acting, lowers BP to suppress outflow to periphery
A2 receptor agonist - Decrease CO and PVR
Clinical Use: Lowers BP
Adverse Effects: Light headedness, sedation, impaired concentration
Question:
2. Propranolol
Answer:
Sympatholytic - inhibitis SNS activity
Block catecholamine action - decrease BP
Non selective B blocker
Clinical Use: Lowers BP, atrial fibrillation, chest pain
Notes: Bronchoconstriction (contraindicated in athmatics)
Question:
3. Metaprolol
Answer:
Sympatholytic - inhibits SNS activity
Block catecholamine actions, decrease BP
Clinical Use: Lower BP, angina, atrial arrhythmia, treat patients with excessive
tachycardia
Notes: No contraindicators
Question:
4. Prazosin
Answer:
Sympatholytic - inhibits SNS activity
Alpha blocker - A1 antagonist
Clinical Use: lowers BP
Adverse Effects: Edema, tachycardia, dizziness, headache, water retention
Baroreceptor reflex mediated
, Question:
5. Sodium Nitroprusside (SNP)
Answer:
Vasodilators
Vasodilation of atrial + venous vessels through guanylyl cyclase activation
Clinical Uses: Heart failure, acute hypertensive emergencies
Adverse Effects: Hypotension. Cyanide toxicity can occur from prolonged drug
administration
Baroreceptor reflex mediated
Question:
6. Verapamil
Answer:
Vasodilator
Decrease Ca2+ levels, contractions decrease, inhibits Ca2+ influx results in
relaxation
Clinical Use: Hypertension, angina
Contraindicated in patients with bradycardia
Anti arrhythmic Class IV: Ca2+ channel blockers
Decrease cardiac contractility + induce vasodilator
Clinical Use: Supraventricular tachycardia
Do not take if low blood pressure present
Question:
7. Enalapril
Answer:
ACE Inhibitor
Ester prodrug converted into active metabolite
Clinical Use: Patients with left ventricular dysfunctions but no edema
Adverse Effects: Dizziness, rash headache
ACTUAL QUESTIONS AND CORRECT ANSWERS
Question:
1. Clonidine
Answer:
Sympatholytic - inhibits SNS activity
Centrally acting, lowers BP to suppress outflow to periphery
A2 receptor agonist - Decrease CO and PVR
Clinical Use: Lowers BP
Adverse Effects: Light headedness, sedation, impaired concentration
Question:
2. Propranolol
Answer:
Sympatholytic - inhibitis SNS activity
Block catecholamine action - decrease BP
Non selective B blocker
Clinical Use: Lowers BP, atrial fibrillation, chest pain
Notes: Bronchoconstriction (contraindicated in athmatics)
Question:
3. Metaprolol
Answer:
Sympatholytic - inhibits SNS activity
Block catecholamine actions, decrease BP
Clinical Use: Lower BP, angina, atrial arrhythmia, treat patients with excessive
tachycardia
Notes: No contraindicators
Question:
4. Prazosin
Answer:
Sympatholytic - inhibits SNS activity
Alpha blocker - A1 antagonist
Clinical Use: lowers BP
Adverse Effects: Edema, tachycardia, dizziness, headache, water retention
Baroreceptor reflex mediated
, Question:
5. Sodium Nitroprusside (SNP)
Answer:
Vasodilators
Vasodilation of atrial + venous vessels through guanylyl cyclase activation
Clinical Uses: Heart failure, acute hypertensive emergencies
Adverse Effects: Hypotension. Cyanide toxicity can occur from prolonged drug
administration
Baroreceptor reflex mediated
Question:
6. Verapamil
Answer:
Vasodilator
Decrease Ca2+ levels, contractions decrease, inhibits Ca2+ influx results in
relaxation
Clinical Use: Hypertension, angina
Contraindicated in patients with bradycardia
Anti arrhythmic Class IV: Ca2+ channel blockers
Decrease cardiac contractility + induce vasodilator
Clinical Use: Supraventricular tachycardia
Do not take if low blood pressure present
Question:
7. Enalapril
Answer:
ACE Inhibitor
Ester prodrug converted into active metabolite
Clinical Use: Patients with left ventricular dysfunctions but no edema
Adverse Effects: Dizziness, rash headache
