BLD 204 EXAM 2 UPDATED ACTUAL QUESTIONS AND
CORRECT ANSWERS
Question:
1. what is immunity?
Answer:
- protection against infection
- freedom from a harmful condition
- immune system is made up of the cells and molecules that defend the body
against pathogens
Question:
2. antigens
Answer:
molecules recognized as non-self (epitope is recognized)
- endogenous: native to self
- exogenous: environmental
Question:
3. antibodies
Answer:
also know as immunoglobulins (Ig)
- one monomeric unit is 2 identical heavy chains and 2 identical light chains
coming together to form 2 AB binding sites
- five classes based on heavy chain structure and how many monomeric units they
have
Question:
4. what do antibodies do?
Answer:
- agglutinate and lyse bacteria
- opsonize bacteria
- initiate classical complement pathway
- neutralize toxins
- block microbe entry into tissues
- assist in killing infected cells
not all classes do all of these
, Question:
5. function of antigen presenting cells
Answer:
- capture and display the Ag flag
- three types: DC dendritic cells, macrophages, and B cells
Question:
6. function of dendritic cells (DC)
Answer:
capture and present antigen to T cells
- express MHC II and T cell costimulatory molecules
- found in the T cell zones in lymphoid tissue
Question:
7. function of macrophages
Answer:
phagocytize and present antigen
Question:
8. function of B cells
Answer:
recognize antigen via BCR, take it in and process it, present via MHC II molecules
to helper Ts
Question:
9. MHC class I
Answer:
- present on nucleated cells
- signal to CD8+ cytotoxic Ts
- heavy α chain and β2 microglobulin chain
Question:
10. MHC class II
Answer:
- present on professional APCs
- antigen is consumed, processed, and presented in MHC II by these cells
- two peptide chains of more equal size
- signal recognized by CD4+ helper Ts
CORRECT ANSWERS
Question:
1. what is immunity?
Answer:
- protection against infection
- freedom from a harmful condition
- immune system is made up of the cells and molecules that defend the body
against pathogens
Question:
2. antigens
Answer:
molecules recognized as non-self (epitope is recognized)
- endogenous: native to self
- exogenous: environmental
Question:
3. antibodies
Answer:
also know as immunoglobulins (Ig)
- one monomeric unit is 2 identical heavy chains and 2 identical light chains
coming together to form 2 AB binding sites
- five classes based on heavy chain structure and how many monomeric units they
have
Question:
4. what do antibodies do?
Answer:
- agglutinate and lyse bacteria
- opsonize bacteria
- initiate classical complement pathway
- neutralize toxins
- block microbe entry into tissues
- assist in killing infected cells
not all classes do all of these
, Question:
5. function of antigen presenting cells
Answer:
- capture and display the Ag flag
- three types: DC dendritic cells, macrophages, and B cells
Question:
6. function of dendritic cells (DC)
Answer:
capture and present antigen to T cells
- express MHC II and T cell costimulatory molecules
- found in the T cell zones in lymphoid tissue
Question:
7. function of macrophages
Answer:
phagocytize and present antigen
Question:
8. function of B cells
Answer:
recognize antigen via BCR, take it in and process it, present via MHC II molecules
to helper Ts
Question:
9. MHC class I
Answer:
- present on nucleated cells
- signal to CD8+ cytotoxic Ts
- heavy α chain and β2 microglobulin chain
Question:
10. MHC class II
Answer:
- present on professional APCs
- antigen is consumed, processed, and presented in MHC II by these cells
- two peptide chains of more equal size
- signal recognized by CD4+ helper Ts
