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AORN Periop 101 Final Exam 2026/2027 – 321 Review Questions & Answers, Sterile Technique, Infection Control, Surgical Safety, Sharps & Radiation

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This AORN Periop 101 Final Exam Review 2026/2027 contains 321 question-and-answer review items covering essential concepts in perioperative nursing and operating-room safety. The 36-page study document begins with preoperative skin preparation, resident bacteria, antimicrobials, antiseptic contact, hair removal, surgical hand hygiene, surgical attire, sterile gowning and gloving, and prevention of surgical site infections. It then progresses through sterile-field management, draping techniques, contamination prevention, operating-room protocols, and perioperative team practices. A major portion of the review addresses pneumatic tourniquet safety and physiology, including ischemia, cuff pressure, contraindications, DVT risk factors, Bier block considerations, local-anesthetic toxicity, and physiologic responses to tourniquet inflation and deflation. The guide also provides extensive review material on the surgical fire triangle, ignition and fuel sources, oxidizers, fire-risk assessment, laser precautions, oxygen management, fire response, evacuation procedures, electrosurgery, dispersive pads, and energy-generating device safety. Infection prevention and occupational safety are covered through questions on environmental cleaning, healthcare disinfectants, Clostridium difficile, CJD, PPE, bloodborne pathogens, OSHA requirements, sharps disposal, hierarchy of controls, needleless systems, neutral zones, double gloving, safety-engineered devices, needlestick injuries, exposure reporting, and post-exposure prophylaxis. The final sections emphasize ionizing radiation, occupational dose monitoring, time-distance-shielding principles, dosimeters, pregnancy precautions, MR safety zones, radioactive materials, perioperative checklists, TIME OUT procedures, RN circulator responsibilities, Phase II recovery, and surgical technologist responsibilities. The document is particularly suited to active recall and final-exam revision because the material is organized into concise concepts followed immediately by answers. The source identifies AORN as the Association of periOperative Registered Nurses and explicitly covers AORN guidelines and perioperative practices. However, it does not identify a university or conventional academic course code; therefore, adding a fabricated university or course number would be inaccurate. For authoritative supplementary study, students can consult the Association of periOperative Registered Nurses (AORN), whose perioperative guidelines address evidence-based practices across the surgical environment. Additional regulatory context is available from the OSHA Bloodborne Pathogens and Needlestick Prevention resource and the CDC Infection Control guidance. These external references provide broader professional context; they should not be interpreted as independently verifying every answer contained in the uploaded review document. Relevant Students: This study guide is relevant to Periop 101 learners, perioperative nursing students, registered nurses transitioning into operating-room nursing, OR nurse trainees, RN circulators, surgical nursing students, perioperative nurse residency participants, surgical technology students, operating-room personnel, and healthcare professionals reviewing infection prevention, sterile technique, sharps safety, surgical fire prevention, radiation safety, and perioperative patient safety. Keywords: AORN Periop 101 final exam, Periop 101 exam questions and answers, AORN final exam 2026, AORN final exam 2027, AORN Periop 101 study guide, perioperative nursing exam, perioperative nursing questions and answers, operating room nursing exam, OR nurse study guide, sterile technique questions, surgical asepsis, surgical hand antisepsis, sterile field management, infection control nursing, surgical site infection prevention, AORN guidelines, perioperative patient safety, surgical fire safety, fire triangle operating room, pneumatic tourniquet safety, electrosurgery safety, laser safety, sharps injury prevention, bloodborne pathogens, OSHA bloodborne pathogens, double gloving, neutral zone sharps, radiation safety nursing, ionizing radiation safety, MR safety zones, RN circulator, surgical technologist, TIME OUT procedure, perioperative checklist, AORN exam review, Periop 101 practice questions

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AORN Periop 101 Final Exam
Review Questions and Answers
2026/2027 Expert Verifed Ace
the Test



Mechanical friction - ANSWER ✔✔Does not remove resident bacteria

effectively.


Resident bacteria - ANSWER ✔✔Bacteria that normally inhabit the

skin.


Antimicrobials - ANSWER ✔✔Agents that inhibit microbial growth.


Chemical burns - ANSWER ✔✔Injury from prolonged antiseptic

contact.

,Thermal burns - ANSWER ✔✔Injury caused by heat from antiseptics.


Povidone-iodine - ANSWER ✔✔Antiseptic that disrupts cell

membranes.


Preoperative skin prep - ANSWER ✔✔Cleans skin to reduce

microbial load.


Hair removal - ANSWER ✔✔Not documented if it doesn't interfere

with surgery.


Clean to dirty prep - ANSWER ✔✔Start cleaning at incision site,

move outward.


Common resident bacteria - ANSWER ✔✔Includes Staphylococcus

and diphtheroid bacilli.


Skin prep documentation - ANSWER ✔✔Includes allergies and prep

performer's name.


Surgical wound infections - ANSWER ✔✔Lead to decreased hospital

income.


Antimicrobial contact time - ANSWER ✔✔Effective after time

specified by manufacturers.

,Prep extremity positioning - ANSWER ✔✔Prevents solution from

running toward incision.


Surgical prep objectives - ANSWER ✔✔Remove dirt, oil, microbes;

prevent regrowth.


Skin sterilization - ANSWER ✔✔Not achievable through skin prep

alone.


Intraoperative time - ANSWER ✔✔Duration of surgery affected by

infections.


Depilatory use - ANSWER ✔✔Not always required for hair removal.


Scrubbing nails - ANSWER ✔✔Important before formal skin

preparation.


AORN guidelines - ANSWER ✔✔Provide standards for patient skin

preparation.


Surgical scrub solutions - ANSWER ✔✔Used before applying

surgical paint.


Injuries from equipment malfunction - ANSWER ✔✔Can occur during

prolonged antiseptic use.


Stomas - ANSWER ✔✔Surgical openings for waste elimination.


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, Chlorhexidine gluconate - ANSWER ✔✔Neurotoxic topical

antimicrobial agent.


Iodophor with alcohol - ANSWER ✔✔Provides rapid microbial

reduction on skin.


Vaginal prep - ANSWER ✔✔The vagina should not be prepped first.


Hand hygiene - ANSWER ✔✔Performed after touching surfaces or

linens.


Alcohol-based rub - ANSWER ✔✔Used when hands are not visibly

soiled.


Hand hygiene duration - ANSWER ✔✔Minimum 15 seconds with

soap and water.


Alcohol-based hand rub amount - ANSWER ✔✔Use manufacturer's

recommended amount.


Fingernail length - ANSWER ✔✔Maximum length is 2 mm (0.08

inch).


Healthy skin measures - ANSWER ✔✔Dry hands completely before

wearing gloves.

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Written in
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