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NSG 5140 EXAM 3 PATHOPHYSIOLOGY EXAM 3 ACTUAL QUESTIONS & ANSWERS /

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Master advanced disease processes and clinical concepts with this high-yield NSG 5140 Exam 3 Pathophysiology Study Guide (2026–2027 Academic Year). Designed specifically for graduate-level nursing and Nurse Practitioner (NP) students, this comprehensive document features authentic practice exam questions, verified correct answers, and detailed rationales grounded in pathophysiological mechanisms.

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NSG 5140 EXAM 3
PATHOPHYSIOLOGY EXAM 3
ACTUAL QUESTIONS & ANSWERS
/2026-2027
The nurse working in an outpatient nephrology clinic knows that which of the following are primary
functions of the kidneys? (Select all that apply.)

A. Production of clotting factors

B. Homeostasis

C. Excretion of metabolic wastes

D. Regulation of acid-base balance

E. Metabolism of fats -Answer B, C, D



The kidneys do not metabolize fats.

Production of clotting factors is a primary function of the liver.

The kidneys maintain blood pressure using the RAAS and also produce erythropoietin to stimulate RBC
production.



In caring for a patient diagnosed with acute kidney injury, the nephrology nurse knows that which of
the following tests are specific for renal function? (Select all that apply.)

A. Aspartate aminotransferase (AST)

B. Blood urea nitrogen

C. Creatinine

,D. Glomerular filtration rate

E. White blood cell count -Answer B, C, D



AST related to LIVER function



In caring for a patient with acute kidney injury the nurse knows that the patient's renal function has
returned to normal range when the patient's GFR measures:

A. 30-40 mL/min

B. 40-50 mL/min

C. 70-90 mL/min

D. 90-120 mL/min -Answer D



Normal GFR is 90-120 mL/min

Normal Creatinine 0.6-1.1 for females and 0.6-1.2 for males

Normal BUN is 10-20 mg/dL



*Be sure to know these normal values, you will use them daily as a nurse



The nursing working in a geriatric living facility understands that as patients age, which change in
glomerular filtration rate is expected?

A. Increased GFR

B. Decreased GFR

C. Same GFR

D. No GFR -Answer B



Aging and renal function:

,Decrease in renal blood flow and GFR → altered sodium and water balance

Number of nephrons decrease due to renal vascular and perfusion changes

Response to acid-base changes is delayed

Increased risk for drug toxicity

Alterations in thirst and water intake

Get dehydrated very easily; do not recognize thirst and heat

Decreased muscle mass may lead to decreased creatinine values



An older patient is experiencing urinary stasis. The registered nurse knows that urinary stasis may
lead to which of the following?

A. Increased GFR

B. Hypocoagulation

C. Hypertension

D. Infection -Answer D



Urinary stasis is a risk factor for developing UTI



Which of the following is classified as the most common primary mineral salt composition of kidney
stones?

A. Calcium

B. Struvite

C. Uric Acid

D. Cysteine -Answer A



A - calcium (i.e. oxalate or phosphate) is most common

, *Note that a change in urine pH may lead to precipitation of stones



Which of the following are risk factors for developing renal tumors? (Select all that apply.)

A. Female gender

B. Smoking

C. Obesity

D. Diabetes

E. Hypertension -Answer B, C, E



risk factors are male gender, smoking, obesity, uncontrolled hypertension



The registered nurse would expect which of the following lab values for a patient experiencing acute
kidney failure?

A. Creatinine 3.5 mg/dL

B. Sodium 122 mEq/L

C. Albumin 3.5 g/dL

D. BUN 10 mg/dL -Answer A




the normal creatinine level is 0.6 - 1.2



This BUN is within normal range (BUN would be elevated in acute kidney failure)



In caring for a patient experiencing acute kidney injury who has these lab values: urinary output 15
mL/hr, BUN 30 mg/dL, and creatinine 3.5, the nurse knows that the patient is experiencing which
phase of acute kidney injury?

A. Initiation phase

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