■ NURSE BARBIE NURSE ■
50 PHARMACOLOGY PRACTICE QUESTIONS
■ PHARMACOLOGY QUEEN EDITION ■
NCLEX-style multiple-choice questions
Answers + concise rationales
Designed for nursing revision
Study tip: Choose your answer first, then check the rationale. Focus on medication class, major adverse effects,
nursing assessments, and patient teaching.
Nurse Barbie Nurse • Pharmacology Revision Page 1
, 1. A client taking warfarin asks which food choice is most important to discuss with the nurse?
A. Maintaining a consistent intake of vitamin K–rich foods
B. Avoiding all carbohydrates
C. Increasing grapefruit juice
D. Taking extra vitamin E daily
Answer: A
Rationale: Warfarin effectiveness is affected by vitamin K. The client should keep vitamin K intake consistent rather than abruptly
increasing or eliminating it.
2. Which medication is classified as a loop diuretic?
A. Spironolactone
B. Furosemide
C. Hydrochlorothiazide
D. Mannitol
Answer: B
Rationale: Furosemide is a loop diuretic that increases sodium and water excretion. It can cause hypokalemia and volume
depletion.
3. A patient receiving digoxin should have which assessment prioritized before administration?
A. Respiratory rate
B. Apical pulse
C. Bowel sounds
D. Temperature
Answer: B
Rationale: Digoxin can slow the heart rate. The apical pulse should be assessed before administration according to prescribed
parameters.
4. Which adverse effect is most associated with ACE inhibitors such as lisinopril?
A. Dry cough
B. Orange urine
C. Severe constipation
D. Hearing loss
Answer: A
Rationale: ACE inhibitors commonly cause a persistent dry cough because of increased bradykinin. Angioedema is a rare but
serious reaction.
5. Which insulin has the fastest onset of action?
A. Glargine
B. NPH
C. Lispro
D. Detemir
Answer: C
Rationale: Insulin lispro is rapid-acting and begins working quickly, making it useful around mealtimes.
6. A client taking metformin is scheduled for iodinated contrast imaging. What should the nurse anticipate?
A. Metformin may need to be temporarily withheld
B. The dose should be doubled
C. Give metformin with the contrast
D. Replace metformin with insulin permanently
Answer: A
Rationale: Metformin may be temporarily withheld around iodinated contrast in appropriate patients because of concern for renal
impairment and lactic acidosis.
Nurse Barbie Nurse • Pharmacology Revision Page 2
50 PHARMACOLOGY PRACTICE QUESTIONS
■ PHARMACOLOGY QUEEN EDITION ■
NCLEX-style multiple-choice questions
Answers + concise rationales
Designed for nursing revision
Study tip: Choose your answer first, then check the rationale. Focus on medication class, major adverse effects,
nursing assessments, and patient teaching.
Nurse Barbie Nurse • Pharmacology Revision Page 1
, 1. A client taking warfarin asks which food choice is most important to discuss with the nurse?
A. Maintaining a consistent intake of vitamin K–rich foods
B. Avoiding all carbohydrates
C. Increasing grapefruit juice
D. Taking extra vitamin E daily
Answer: A
Rationale: Warfarin effectiveness is affected by vitamin K. The client should keep vitamin K intake consistent rather than abruptly
increasing or eliminating it.
2. Which medication is classified as a loop diuretic?
A. Spironolactone
B. Furosemide
C. Hydrochlorothiazide
D. Mannitol
Answer: B
Rationale: Furosemide is a loop diuretic that increases sodium and water excretion. It can cause hypokalemia and volume
depletion.
3. A patient receiving digoxin should have which assessment prioritized before administration?
A. Respiratory rate
B. Apical pulse
C. Bowel sounds
D. Temperature
Answer: B
Rationale: Digoxin can slow the heart rate. The apical pulse should be assessed before administration according to prescribed
parameters.
4. Which adverse effect is most associated with ACE inhibitors such as lisinopril?
A. Dry cough
B. Orange urine
C. Severe constipation
D. Hearing loss
Answer: A
Rationale: ACE inhibitors commonly cause a persistent dry cough because of increased bradykinin. Angioedema is a rare but
serious reaction.
5. Which insulin has the fastest onset of action?
A. Glargine
B. NPH
C. Lispro
D. Detemir
Answer: C
Rationale: Insulin lispro is rapid-acting and begins working quickly, making it useful around mealtimes.
6. A client taking metformin is scheduled for iodinated contrast imaging. What should the nurse anticipate?
A. Metformin may need to be temporarily withheld
B. The dose should be doubled
C. Give metformin with the contrast
D. Replace metformin with insulin permanently
Answer: A
Rationale: Metformin may be temporarily withheld around iodinated contrast in appropriate patients because of concern for renal
impairment and lactic acidosis.
Nurse Barbie Nurse • Pharmacology Revision Page 2
