ACRP CCRA | ASSOCIATION OF CLINICAL RESEARCH
PROFESSIONALS (ACRP) CERTIFIED CLINICAL RESEARCH
ASSOCIATE EXAM ACTUAL EXAM 2026 || MOST RECENT
EXAM 2026|2027 ACTUAL COMPLETE REAL EXAM QUESTIONS
AND CORRECT ANSWERS (VERIFIED ANSWERS) ALREADY
GRADED A+ | GUARANTEED SUCCESS!! NEWEST EXAM | JUST
RELEASED!!
Which statement about equivalence margin is NOT true?
a) The equivalence margin should be specified in protocol
b) The equivalence margin is the largest difference that can be judged
as being clinically acceptable
c) Equivalence is inferred when entire confidence interval falls within
equivalence margin
d) Equivalence margin should be same as difference observed in
superiority trials of active comparator -ANSWERS-d) Equivalence
margin should be same as difference observed in superiority trials of
active comparator
What techniques reduce bias? -ANSWERS-- Blinding
- Randomization
Which is NOT true about Double Dummy trials?
,a) Double Dummy may be single-blind or double-blind
b) Double Dummy is a placebo-controlled trial
c) Double Dummy enables blinding for products that have different
physical appearance
d) Double Dummy enables blinding for products which have different
administration schedule -ANSWERS-b) Double Dummy is a placebo-
controlled trial
Which results of trial conduct issues have statistical impact? -ANSWERS-
- Changes to IC/EC
- Trialing accural rates
- Sample size adjustments
According to ICH E9, IDMCs should provide what? -ANSWERS-- Intervals
assess the safety of clinical trial
- Recommend to sponsor whether to continue, modify, or stop trial
Which are for full-analysis sample set? -ANSWERS-- Includes all
randomized subjects
- Complete follow-up of all randomized subjects for study outcomes if
necessary
- Most likely to mirror normal day to day practice
,Which are for a per-protocol sample set? -ANSWERS-- Completion of
pre-specified minimal exposure to treatment is necessary
- Availability of measurements of primary variable is necessary
- No major protocol violations nor violation of entry criteria
Investigator continues to randomize patient until patient is grouped
with investigators desired product. Is this ethical? -ANSWERS-No
Data manager suspects fraud and immediately calls investigator stating
fraud was committed. Was this the best course of action? -ANSWERS-
No
What must or may the physician do with regard to unproven
intervention? (Declaration of Helsinki) -ANSWERS-May consider an
unproved intervention
Who can detect fraud/misconduct? -ANSWERS-Site staff, trial subject,
auditors/inspectors, CRA, data entry personnel or data manager,
whistle blower, writer of final trial report
Investigator continues postponing dates for QC. Is this unethical
behavior? -ANSWERS-Yes
, When selecting trial site, which does the selector need to be vigilant
about regarding ethics? -ANSWERS-Investigator and site staff have
potential subjects and resources to conduct trial according to protocol
What are three key principles of the Belmont Report? -ANSWERS--
Respect for persons
- Justice
- Beneficence
True or False? Nuremberg Code states human subjects should be at
liberty to withdraw. -ANSWERS-True
True or False? A site has limited resources and the investigator is
promised a trip if enrollment increases. The CRA claims this is ethical. -
ANSWERS-False
True or False? There's no need to review/cross-check because unethical
conduct almost never occurs anymore. -ANSWERS-False
Inspection objective include verifying? -ANSWERS-- Rights, safety,
welfare of subjects
- Compliance with regulations
- Adherence to pharmacovigilance requirements
- Data integrity of submitted data and reports
PROFESSIONALS (ACRP) CERTIFIED CLINICAL RESEARCH
ASSOCIATE EXAM ACTUAL EXAM 2026 || MOST RECENT
EXAM 2026|2027 ACTUAL COMPLETE REAL EXAM QUESTIONS
AND CORRECT ANSWERS (VERIFIED ANSWERS) ALREADY
GRADED A+ | GUARANTEED SUCCESS!! NEWEST EXAM | JUST
RELEASED!!
Which statement about equivalence margin is NOT true?
a) The equivalence margin should be specified in protocol
b) The equivalence margin is the largest difference that can be judged
as being clinically acceptable
c) Equivalence is inferred when entire confidence interval falls within
equivalence margin
d) Equivalence margin should be same as difference observed in
superiority trials of active comparator -ANSWERS-d) Equivalence
margin should be same as difference observed in superiority trials of
active comparator
What techniques reduce bias? -ANSWERS-- Blinding
- Randomization
Which is NOT true about Double Dummy trials?
,a) Double Dummy may be single-blind or double-blind
b) Double Dummy is a placebo-controlled trial
c) Double Dummy enables blinding for products that have different
physical appearance
d) Double Dummy enables blinding for products which have different
administration schedule -ANSWERS-b) Double Dummy is a placebo-
controlled trial
Which results of trial conduct issues have statistical impact? -ANSWERS-
- Changes to IC/EC
- Trialing accural rates
- Sample size adjustments
According to ICH E9, IDMCs should provide what? -ANSWERS-- Intervals
assess the safety of clinical trial
- Recommend to sponsor whether to continue, modify, or stop trial
Which are for full-analysis sample set? -ANSWERS-- Includes all
randomized subjects
- Complete follow-up of all randomized subjects for study outcomes if
necessary
- Most likely to mirror normal day to day practice
,Which are for a per-protocol sample set? -ANSWERS-- Completion of
pre-specified minimal exposure to treatment is necessary
- Availability of measurements of primary variable is necessary
- No major protocol violations nor violation of entry criteria
Investigator continues to randomize patient until patient is grouped
with investigators desired product. Is this ethical? -ANSWERS-No
Data manager suspects fraud and immediately calls investigator stating
fraud was committed. Was this the best course of action? -ANSWERS-
No
What must or may the physician do with regard to unproven
intervention? (Declaration of Helsinki) -ANSWERS-May consider an
unproved intervention
Who can detect fraud/misconduct? -ANSWERS-Site staff, trial subject,
auditors/inspectors, CRA, data entry personnel or data manager,
whistle blower, writer of final trial report
Investigator continues postponing dates for QC. Is this unethical
behavior? -ANSWERS-Yes
, When selecting trial site, which does the selector need to be vigilant
about regarding ethics? -ANSWERS-Investigator and site staff have
potential subjects and resources to conduct trial according to protocol
What are three key principles of the Belmont Report? -ANSWERS--
Respect for persons
- Justice
- Beneficence
True or False? Nuremberg Code states human subjects should be at
liberty to withdraw. -ANSWERS-True
True or False? A site has limited resources and the investigator is
promised a trip if enrollment increases. The CRA claims this is ethical. -
ANSWERS-False
True or False? There's no need to review/cross-check because unethical
conduct almost never occurs anymore. -ANSWERS-False
Inspection objective include verifying? -ANSWERS-- Rights, safety,
welfare of subjects
- Compliance with regulations
- Adherence to pharmacovigilance requirements
- Data integrity of submitted data and reports
