Nursing Study Guide & Exam Prep 2026/2027 | Psychiatric
Nursing Practice Questions, Therapeutic Communication,
Mental Status Assessment, Psychopharmacology, Anxiety &
Mood Disorders, Schizophrenia, Substance Use, Crisis
Intervention, Patient Safety, Clinical Judgment & Detailed
Rationales
Question 1: A client diagnosed with major depressive disorder is started on
phenelzine. Which dietary instruction is most critical for the nurse to provide?
A. Increase intake of aged cheeses and red wine.
B. Avoid foods high in tyramine, such as salami and sauerkraut.
C. Supplement the diet with foods rich in tryptophan.
D. Restrict fluid intake to 1.5 liters per day.
CORRECT ANSWER: B. Avoid foods high in tyramine, such as salami and
sauerkraut.
Rationale: Phenelzine is a monoamine oxidase inhibitor (MAOI). MAOIs block the
breakdown of tyramine, potentially leading to a hypertensive crisis if tyramine-rich foods
are consumed. Salami and sauerkraut are high in tyramine.
Question 2: A nurse is caring for a client with schizophrenia who reports
hearing voices that tell them they are "evil." Which nursing intervention is the
priority?
A. Ask the client to describe the content and frequency of the voices.
B. Tell the client that the voices are not real and should be ignored.
C. Encourage the client to participate in a group activity.
D. Place the client in seclusion until the voices stop.
CORRECT ANSWER: A. Ask the client to describe the content and frequency of
the voices.
Rationale: The priority is to assess the nature of the hallucinations, specifically looking
for command hallucinations that could instruct the client to harm themselves or others.
This ensures client safety while maintaining therapeutic communication.
Question 3: A client with bipolar disorder is prescribed lithium. Which
laboratory value should the nurse monitor most closely to prevent toxicity?
A. Serum sodium
B. Serum potassium
C. Serum calcium
D. Serum magnesium
CORRECT ANSWER: A. Serum sodium
,Rationale: Lithium excretion is directly related to serum sodium levels. Low sodium
levels cause the kidneys to retain lithium, increasing the risk of toxicity. Hyponatremia
can occur due to diuretic use, sweating, or dehydration.
Question 4: A client with borderline personality disorder uses splitting as a
primary defense mechanism. Which statement by the client best reflects this
behavior?
A. "I feel like I'm falling apart and can't keep myself together."
B. "You are the only nurse who understands me; the other one is incompetent."
C. "I don't remember what happened during the argument."
D. "I know I have a problem, but I refuse to take medication."
CORRECT ANSWER: B. "You are the only nurse who understands me; the other
one is incompetent."
Rationale: Splitting is the inability to integrate positive and negative aspects of self or
others, leading to viewing people as all good or all bad. This statement idealizes one
nurse while devaluing another, a classic presentation of splitting.
Question 5: A client with post-traumatic stress disorder (PTSD) experiences
recurrent nightmares and flashbacks. Which medication classification is
considered first-line pharmacotherapy for this condition?
A. Benzodiazepines
B. Atypical antipsychotics
C. Selective Serotonin Reuptake Inhibitors (SSRIs)
D. Tricyclic antidepressants
CORRECT ANSWER: C. Selective Serotonin Reuptake Inhibitors (SSRIs)
Rationale: SSRIs (e.g., sertraline, paroxetine) are the first-line pharmacological treatment
for PTSD. They are effective in reducing core symptoms such as intrusive thoughts,
nightmares, and hyperarousal.
Question 6: A nurse is assessing a client for alcohol withdrawal. Which
symptom would indicate the potential for severe withdrawal and seizures?
A. Insomnia and anxiety
B. Nausea and vomiting
C. Diaphoresis and tachycardia
D. Tremors and hallucinations
CORRECT ANSWER: D. Tremors and hallucinations
,Rationale: The presence of tremors (specifically gross tremors) and hallucinations
indicates severe alcohol withdrawal, often progressing to delirium tremens, which is a
medical emergency associated with seizures and cardiovascular collapse.
Question 7: A client with obsessive-compulsive disorder (OCD) spends 3 hours
daily washing their hands. What is the primary purpose of this compulsive
behavior?
A. To reduce anxiety related to contamination obsessions.
B. To gain attention from family members.
C. To physically remove dirt from the skin.
D. To punish themselves for unwanted thoughts.
CORRECT ANSWER: A. To reduce anxiety related to contamination obsessions.
Rationale: Compulsions are repetitive behaviors performed to neutralize or reduce the
anxiety caused by obsessions. The handwashing ritual directly targets the obsession
with contamination to temporarily decrease distress.
Question 8: A client is admitted with anorexia nervosa. The nurse notes a
body mass index (BMI) of 15. Which physiological finding is most concerning
and requires immediate intervention?
A. Lanugo hair on the back
B. Bradycardia with a heart rate of 48 bpm
C. Dry, brittle hair and nails
D. Amenorrhea
CORRECT ANSWER: B. Bradycardia with a heart rate of 48 bpm
Rationale: Bradycardia is a sign of severe malnutrition and cardiac muscle wasting. A
heart rate of 48 is critically low and indicates the heart is struggling to pump blood,
which could lead to sudden cardiac arrest and requires immediate medical evaluation.
Question 9: A client with dementia is wandering the hallways and attempting
to leave the unit. Which intervention is most appropriate to address this
behavior?
A. Apply a physical restraint to prevent injury.
B. Use a calm voice and redirect the client to a safe activity.
C. Tell the client they must return to their room immediately.
D. Administer a PRN dose of haloperidol.
CORRECT ANSWER: B. Use a calm voice and redirect the client to a safe
activity.
, Rationale: Wandering is common in dementia and often has an unmet need (e.g.,
boredom, hunger). The least restrictive, most therapeutic intervention is redirection with
a calm demeanor to a safe, engaging activity. Restraints are a last resort.
Question 10: A nurse is educating a client about benzodiazepine therapy for
generalized anxiety disorder. What is the most significant risk associated with
long-term use?
A. Weight gain
B. Sexual dysfunction
C. Physical dependence and withdrawal
D. Hepatotoxicity
CORRECT ANSWER: C. Physical dependence and withdrawal
Rationale: Benzodiazepines have a high potential for physical dependence and tolerance.
Abrupt discontinuation can lead to severe withdrawal symptoms, including rebound
anxiety, insomnia, and potentially life-threatening seizures.
Question 11: A client with antisocial personality disorder is manipulative and
frequently breaks unit rules. Which nursing approach is most effective?
A. Allowing flexible rules to prevent the client from becoming angry.
B. Confronting the client about their manipulative behaviors openly.
C. Setting firm, consistent limits with clear consequences.
D. Avoiding the client to minimize interactions.
CORRECT ANSWER: C. Setting firm, consistent limits with clear consequences.
Rationale: Clients with antisocial personality disorder require clear, consistent
boundaries and consequences to prevent manipulation. A unified team approach with
consistent limit-setting is crucial for safety and therapeutic progress.
Question 12: A client presents to the emergency department with sudden onset
of severe anxiety, palpitations, chest pain, and fear of dying. These symptoms
began abruptly 15 minutes ago. Which condition is most likely?
A. Generalized anxiety disorder
B. Panic attack
C. Social anxiety disorder
D. Agoraphobia
CORRECT ANSWER: B. Panic attack