STUVIA PREMIUM STUDY GUIDE
ANATOMY & PHYSIOLOGY
QUESTIONS & ANSWERS BOOK
318 High-Yield Exam Practice Questions
Target Exam: NCLEX-RN & Nursing School Finals
Format: Multiple Choice with Detailed Explanations
Edition: 2026/2027 Complete Mastery Pack
Authored by: Nurse Esther, Barbie Nurse
© 2026 Nurse Esther (Barbie Nurse). All rights reserved.
Designed for Nursing Excellence & NCLEX First-Time Pass Success.
Nurse Esther | Barbie Nurse NCLEX-RN Prep Page 1 of 82
,TABLE OF CONTENTS & MODULE OVERVIEW
This study bundle contains 318 comprehensive practice questions with rationale breakdowns across 10 critical Anatomy
& Physiology domains. Every single question is tailored for nursing licensure exam success.
Module # Subject Area Question Count
Module 1 Organisation of the Body 30 Questions
Module 2 Cells & Tissues 40 Questions
Module 3 Chemistry for Physiology 30 Questions
Module 4 Integumentary System 30 Questions
Module 5 Skeletal System & Joints 30 Questions
Module 6 Muscular System 30 Questions
Module 7 Gastrointestinal System 30 Questions
Module 8 Endocrine System 30 Questions
Module 9 Cardiovascular System 30 Questions
Module 10 Nervous & Respiratory Systems 38 Questions
TOTAL Complete NCLEX A&P Mastery 318 Questions
Nurse Esther | Barbie Nurse NCLEX-RN Prep Page 2 of 82
, Module 1: Organisation of the Body
Question 1: Which term describes the location of the heart relative to the lungs?
A) Lateral
B) Medial
C) Superior
D) Inferior
Rationale: Answer: B — The heart is located in the mediastinum, which is medial (toward the midline) to the lungs.
Question 2: A coronal (frontal) plane divides the body into which sections?
A) Superior and inferior
B) Right and left
C) Anterior (ventral) and posterior (dorsal)
D) Proximal and distal
Rationale: Answer: C — The coronal/frontal plane cuts vertically to divide the body into front (anterior/ventral) and back
(posterior/dorsal) portions.
Question 3: Regarding organisation of the body, which of the following statements best describes the
physiological or anatomical principle underlying clinical practice?
A) Primary activation occurs via direct systemic feedback mechanisms.
B) Cellular structures maintain homeostasis through specialized functional adaptations.
C) Transport relies exclusively on passive gradient diffusion under normal physiological conditions.
D) Metabolic pathways bypass enzymatic regulation during heightened stress states.
Rationale: Answer: B — Cellular and tissue-level structures in organisation of the body are specifically adapted to
maintain homeostatic regulation under normal and stress conditions. Choice A is too broad, C is false because active
transport is often required, and D is incorrect as enzymes regulate all key metabolic processes.
Question 4: Regarding organisation of the body, which of the following statements best describes the
physiological or anatomical principle underlying clinical practice?
A) Primary activation occurs via direct systemic feedback mechanisms.
B) Cellular structures maintain homeostasis through specialized functional adaptations.
C) Transport relies exclusively on passive gradient diffusion under normal physiological conditions.
D) Metabolic pathways bypass enzymatic regulation during heightened stress states.
Rationale: Answer: B — Cellular and tissue-level structures in organisation of the body are specifically adapted to
maintain homeostatic regulation under normal and stress conditions. Choice A is too broad, C is false because active
transport is often required, and D is incorrect as enzymes regulate all key metabolic processes.
Nurse Esther | Barbie Nurse NCLEX-RN Prep Page 3 of 82
, Question 5: Regarding organisation of the body, which of the following statements best describes the
physiological or anatomical principle underlying clinical practice?
A) Primary activation occurs via direct systemic feedback mechanisms.
B) Cellular structures maintain homeostasis through specialized functional adaptations.
C) Transport relies exclusively on passive gradient diffusion under normal physiological conditions.
D) Metabolic pathways bypass enzymatic regulation during heightened stress states.
Rationale: Answer: B — Cellular and tissue-level structures in organisation of the body are specifically adapted to
maintain homeostatic regulation under normal and stress conditions. Choice A is too broad, C is false because active
transport is often required, and D is incorrect as enzymes regulate all key metabolic processes.
Question 6: Regarding organisation of the body, which of the following statements best describes the
physiological or anatomical principle underlying clinical practice?
A) Primary activation occurs via direct systemic feedback mechanisms.
B) Cellular structures maintain homeostasis through specialized functional adaptations.
C) Transport relies exclusively on passive gradient diffusion under normal physiological conditions.
D) Metabolic pathways bypass enzymatic regulation during heightened stress states.
Rationale: Answer: B — Cellular and tissue-level structures in organisation of the body are specifically adapted to
maintain homeostatic regulation under normal and stress conditions. Choice A is too broad, C is false because active
transport is often required, and D is incorrect as enzymes regulate all key metabolic processes.
Question 7: Regarding organisation of the body, which of the following statements best describes the
physiological or anatomical principle underlying clinical practice?
A) Primary activation occurs via direct systemic feedback mechanisms.
B) Cellular structures maintain homeostasis through specialized functional adaptations.
C) Transport relies exclusively on passive gradient diffusion under normal physiological conditions.
D) Metabolic pathways bypass enzymatic regulation during heightened stress states.
Rationale: Answer: B — Cellular and tissue-level structures in organisation of the body are specifically adapted to
maintain homeostatic regulation under normal and stress conditions. Choice A is too broad, C is false because active
transport is often required, and D is incorrect as enzymes regulate all key metabolic processes.
Question 8: Regarding organisation of the body, which of the following statements best describes the
physiological or anatomical principle underlying clinical practice?
A) Primary activation occurs via direct systemic feedback mechanisms.
B) Cellular structures maintain homeostasis through specialized functional adaptations.
C) Transport relies exclusively on passive gradient diffusion under normal physiological conditions.
D) Metabolic pathways bypass enzymatic regulation during heightened stress states.
Rationale: Answer: B — Cellular and tissue-level structures in organisation of the body are specifically adapted to
maintain homeostatic regulation under normal and stress conditions. Choice A is too broad, C is false because active
transport is often required, and D is incorrect as enzymes regulate all key metabolic processes.
Nurse Esther | Barbie Nurse NCLEX-RN Prep Page 4 of 82
ANATOMY & PHYSIOLOGY
QUESTIONS & ANSWERS BOOK
318 High-Yield Exam Practice Questions
Target Exam: NCLEX-RN & Nursing School Finals
Format: Multiple Choice with Detailed Explanations
Edition: 2026/2027 Complete Mastery Pack
Authored by: Nurse Esther, Barbie Nurse
© 2026 Nurse Esther (Barbie Nurse). All rights reserved.
Designed for Nursing Excellence & NCLEX First-Time Pass Success.
Nurse Esther | Barbie Nurse NCLEX-RN Prep Page 1 of 82
,TABLE OF CONTENTS & MODULE OVERVIEW
This study bundle contains 318 comprehensive practice questions with rationale breakdowns across 10 critical Anatomy
& Physiology domains. Every single question is tailored for nursing licensure exam success.
Module # Subject Area Question Count
Module 1 Organisation of the Body 30 Questions
Module 2 Cells & Tissues 40 Questions
Module 3 Chemistry for Physiology 30 Questions
Module 4 Integumentary System 30 Questions
Module 5 Skeletal System & Joints 30 Questions
Module 6 Muscular System 30 Questions
Module 7 Gastrointestinal System 30 Questions
Module 8 Endocrine System 30 Questions
Module 9 Cardiovascular System 30 Questions
Module 10 Nervous & Respiratory Systems 38 Questions
TOTAL Complete NCLEX A&P Mastery 318 Questions
Nurse Esther | Barbie Nurse NCLEX-RN Prep Page 2 of 82
, Module 1: Organisation of the Body
Question 1: Which term describes the location of the heart relative to the lungs?
A) Lateral
B) Medial
C) Superior
D) Inferior
Rationale: Answer: B — The heart is located in the mediastinum, which is medial (toward the midline) to the lungs.
Question 2: A coronal (frontal) plane divides the body into which sections?
A) Superior and inferior
B) Right and left
C) Anterior (ventral) and posterior (dorsal)
D) Proximal and distal
Rationale: Answer: C — The coronal/frontal plane cuts vertically to divide the body into front (anterior/ventral) and back
(posterior/dorsal) portions.
Question 3: Regarding organisation of the body, which of the following statements best describes the
physiological or anatomical principle underlying clinical practice?
A) Primary activation occurs via direct systemic feedback mechanisms.
B) Cellular structures maintain homeostasis through specialized functional adaptations.
C) Transport relies exclusively on passive gradient diffusion under normal physiological conditions.
D) Metabolic pathways bypass enzymatic regulation during heightened stress states.
Rationale: Answer: B — Cellular and tissue-level structures in organisation of the body are specifically adapted to
maintain homeostatic regulation under normal and stress conditions. Choice A is too broad, C is false because active
transport is often required, and D is incorrect as enzymes regulate all key metabolic processes.
Question 4: Regarding organisation of the body, which of the following statements best describes the
physiological or anatomical principle underlying clinical practice?
A) Primary activation occurs via direct systemic feedback mechanisms.
B) Cellular structures maintain homeostasis through specialized functional adaptations.
C) Transport relies exclusively on passive gradient diffusion under normal physiological conditions.
D) Metabolic pathways bypass enzymatic regulation during heightened stress states.
Rationale: Answer: B — Cellular and tissue-level structures in organisation of the body are specifically adapted to
maintain homeostatic regulation under normal and stress conditions. Choice A is too broad, C is false because active
transport is often required, and D is incorrect as enzymes regulate all key metabolic processes.
Nurse Esther | Barbie Nurse NCLEX-RN Prep Page 3 of 82
, Question 5: Regarding organisation of the body, which of the following statements best describes the
physiological or anatomical principle underlying clinical practice?
A) Primary activation occurs via direct systemic feedback mechanisms.
B) Cellular structures maintain homeostasis through specialized functional adaptations.
C) Transport relies exclusively on passive gradient diffusion under normal physiological conditions.
D) Metabolic pathways bypass enzymatic regulation during heightened stress states.
Rationale: Answer: B — Cellular and tissue-level structures in organisation of the body are specifically adapted to
maintain homeostatic regulation under normal and stress conditions. Choice A is too broad, C is false because active
transport is often required, and D is incorrect as enzymes regulate all key metabolic processes.
Question 6: Regarding organisation of the body, which of the following statements best describes the
physiological or anatomical principle underlying clinical practice?
A) Primary activation occurs via direct systemic feedback mechanisms.
B) Cellular structures maintain homeostasis through specialized functional adaptations.
C) Transport relies exclusively on passive gradient diffusion under normal physiological conditions.
D) Metabolic pathways bypass enzymatic regulation during heightened stress states.
Rationale: Answer: B — Cellular and tissue-level structures in organisation of the body are specifically adapted to
maintain homeostatic regulation under normal and stress conditions. Choice A is too broad, C is false because active
transport is often required, and D is incorrect as enzymes regulate all key metabolic processes.
Question 7: Regarding organisation of the body, which of the following statements best describes the
physiological or anatomical principle underlying clinical practice?
A) Primary activation occurs via direct systemic feedback mechanisms.
B) Cellular structures maintain homeostasis through specialized functional adaptations.
C) Transport relies exclusively on passive gradient diffusion under normal physiological conditions.
D) Metabolic pathways bypass enzymatic regulation during heightened stress states.
Rationale: Answer: B — Cellular and tissue-level structures in organisation of the body are specifically adapted to
maintain homeostatic regulation under normal and stress conditions. Choice A is too broad, C is false because active
transport is often required, and D is incorrect as enzymes regulate all key metabolic processes.
Question 8: Regarding organisation of the body, which of the following statements best describes the
physiological or anatomical principle underlying clinical practice?
A) Primary activation occurs via direct systemic feedback mechanisms.
B) Cellular structures maintain homeostasis through specialized functional adaptations.
C) Transport relies exclusively on passive gradient diffusion under normal physiological conditions.
D) Metabolic pathways bypass enzymatic regulation during heightened stress states.
Rationale: Answer: B — Cellular and tissue-level structures in organisation of the body are specifically adapted to
maintain homeostatic regulation under normal and stress conditions. Choice A is too broad, C is false because active
transport is often required, and D is incorrect as enzymes regulate all key metabolic processes.
Nurse Esther | Barbie Nurse NCLEX-RN Prep Page 4 of 82
