QUESTIONS & ANSWERS A+ GRADE LATEST STUDY
GUIDE (2026)
Which statement is true regarding cancer? (Select all that apply.)
a. The greater the undifferentiated cell count, the more
aggressive the cancer.
b. Malignant tumors have the potential to kill the host.
c. Benign tumors grow rapidly than malignant ones.
d. Anaplasia means more differentiated cells.
e. Metastasis means less differentiated cells.
a. The greater the undifferentiated cell count, the more
aggressive the cancer.
b. Malignant tumors have the potential to kill the host.
Rationale:The greater the degree of anaplasia, the more
aggressive the malignant tumor.Malignant tumors, if left
untreated, have the potential to kill.Benign tumors often grow
slowly than malignant ones.Anaplasia is a lack of cell
differentiation.Metastasis means the invasion of cancer to distant
sites.
Which is a pathophysiologic change that is consistent with
Alzheimer disease? (Select all that apply)
a. Amyloid plaques
b. Epileptogenic focus
,c. Focal cerebral infarct
d. Neurofibrillary tangles
e. Abnormal serotonin system
a. Amyloid plaques
d. Neurofibrillary tangles
Amyloid plaques and neurofibrillary tangles occur in the brains
of Alzheimer patients and are found at autopsy. Neural thread
proteins (tau protein) have a normal function and stabilize
microtubules. In Alzheimer disease, they are chemically altered
and twist into paired helical filaments known as neurofibrillary
tangles. Epileptogenic focus is associated with seizure disorder.
Focal cerebral infarct is a stroke occurring in a localized area of
the brain. Abnormalities in the cholinergic system are associated
with Alzheimer disease; serotonin abnormalities are found in
depression.
Which statement regarding chronic myeloid leukemia (CML) is a
true statement?
a. It is not seen in children.
b. It represents 30% of all cases of leukemia.
c. The average age of onset is older than 70 years.
d. Affected persons carry the Philadelphia chromosome.
d. Affected persons carry the Philadelphia chromosome.
,Philadelphia chromosome occurs in this leukemia. CML occurs
occasionally in children and adolescents. CML represents
approximately 15% of all cases of leukemia in the US. The
average age of onset is between 40-50 years.
Which term is used to describe an excess of red blood cells?
a. Anemia
b. Polycythemia
c. Pancytopenia
d. Granulocytopenia
b. Polycythemia
- Polycythemia is an excess of red blood cells.
- Anemia is a deficiency of red blood cells.
- Pancytopenia is a decrease in red blood cells, white blood cells,
and platelets.
- Granulocytopenia is a decrease in platelets
It is true that acute lymphoid leukemia (ALL) is
a. Incurable
b. More curable in adults
c. Primarily diagnosed in children
, d. Generally seen in adults older than 70 years
c. Primarily diagnosed in children
ALL is primarily a disorder occurring in children. ALL is highly
curable in children, less so in adults. Peak incidence is between
ages 3-7 years of age. A second rise occurs in middle age
An enlarged thyroid gland produces a colloid goiter when
a. Lack of iodine prevents formation of thyroid-stimulating
hormone without stopping T4 and T3 production
b. Lack of iodine prevents T4 and T3 but without stopping
thyroglobulin formation
c. Excessive iodine suppresses thyroid-stimulating hormone, T4,
and T3 formation
d. Dietary iodine is insufficient and replaced with iodized salt
b. Lack of iodine prevents T4 and T3 but without stopping
thyroglobulin formation
Which is a modifiable risk factor for prevention of
atherosclerosis?
a. Smoking
b. Genetics
c. Gender