Unit 4: Laboratory Techniques and their Application
Assignment C: Making a headache tablet.
Preparation of aspirin
, Introduction
Aspirin is a medication which is used to reduce pain, fevers, and inflammations, swelling, muscle
aches and toothaches. In the past, aspirin was made from willow bark which could contain silicon
which is a precursor to aspirin.
Aim
The aim of this experiment is to synthesis aspirin and to check the boiling point and purity by TLC
and melting point.
Risk assessment
Hazardous chemicals during this experiment are phosphoric acid, which is corrosive, ethanoic acid
which is highly corrosive, flammable and irritant, 2-hydroxbenzie acid (salicylic acid) which is
corrosive and irritant, aspirin (acetysaic acid) is irritant, ethanoic acid is corrosive and flammable,
isopropanol is highly flammable and irritant and a heating metal plate and heating mantle (iomante)
can lead to burns also, glassware which can lead to breakages and cuts. To reduce these risks, we
wear lab coats, goggles, and gloves in case these risks do happen, emergency procedures are to
wash your hands with plenty of cold water and to inform your teacher.
Equipment
- Round bottom flask, isomantle (heating mantle).
- Plastic pipettes, Buchner filter and clips.
- Stopper, two filter papers and clamp stands.
- Condenser, deionized wate and a beaker.
keywords
recrystallization= A technique used to purify crystals
filtration= The process to separate solids from crystals or gases
impurities= “The state of quantity of being impure.”
Crystallization = “The process where crystals are formed that has been melted or from a solution”.
Stage 1: Making crude aspirin under reflux.
Assignment C: Making a headache tablet.
Preparation of aspirin
, Introduction
Aspirin is a medication which is used to reduce pain, fevers, and inflammations, swelling, muscle
aches and toothaches. In the past, aspirin was made from willow bark which could contain silicon
which is a precursor to aspirin.
Aim
The aim of this experiment is to synthesis aspirin and to check the boiling point and purity by TLC
and melting point.
Risk assessment
Hazardous chemicals during this experiment are phosphoric acid, which is corrosive, ethanoic acid
which is highly corrosive, flammable and irritant, 2-hydroxbenzie acid (salicylic acid) which is
corrosive and irritant, aspirin (acetysaic acid) is irritant, ethanoic acid is corrosive and flammable,
isopropanol is highly flammable and irritant and a heating metal plate and heating mantle (iomante)
can lead to burns also, glassware which can lead to breakages and cuts. To reduce these risks, we
wear lab coats, goggles, and gloves in case these risks do happen, emergency procedures are to
wash your hands with plenty of cold water and to inform your teacher.
Equipment
- Round bottom flask, isomantle (heating mantle).
- Plastic pipettes, Buchner filter and clips.
- Stopper, two filter papers and clamp stands.
- Condenser, deionized wate and a beaker.
keywords
recrystallization= A technique used to purify crystals
filtration= The process to separate solids from crystals or gases
impurities= “The state of quantity of being impure.”
Crystallization = “The process where crystals are formed that has been melted or from a solution”.
Stage 1: Making crude aspirin under reflux.
