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Nursing 354 Immune System Nursing
Exam Questions And Correct Answers
(Verified Answers) Plus Rationales 2026
Q&A Instant Download Pdf
___________________________________________________________________
1. Which component of the immune system provides the body's first line of
defense against pathogens?
A. Antibodies
B. Skin and mucous membranes
C. T lymphocytes
D. B lymphocytes
Answer: B. Skin and mucous membranes
Rationale: Skin and mucous membranes form physical and chemical barriers
that prevent many pathogens from entering the body.
2. Which type of immunity develops after a person receives a vaccine?
A. Natural passive immunity
B. Artificial passive immunity
C. Artificial active immunity
D. Natural active immunity
Answer: C. Artificial active immunity
,Rationale: Vaccination exposes the immune system to antigens, stimulating an
active immune response and formation of memory cells.
3. Which white blood cell is primarily responsible for producing antibodies?
A. Neutrophil
B. B lymphocyte
C. Natural killer cell
D. Monocyte
Answer: B. B lymphocyte
Rationale: B lymphocytes differentiate into plasma cells that produce antibodies
against specific antigens.
4. Which immunoglobulin is most abundant in the blood and provides long-
term systemic protection?
A. IgA
B. IgE
C. IgM
D. IgG
Answer: D. IgG
Rationale: IgG is the most abundant immunoglobulin in serum and provides
significant protection against many bacterial and viral infections.
5. Which immunoglobulin is primarily associated with allergic reactions?
A. IgE
B. IgG
C. IgA
D. IgM
Answer: A. IgE
Rationale: IgE binds to mast cells and basophils and plays a major role in
immediate hypersensitivity and allergic reactions.
, 6. Which immunoglobulin is found primarily in secretions such as saliva, tears,
and breast milk?
A. IgM
B. IgA
C. IgG
D. IgE
Answer: B. IgA
Rationale: IgA protects mucosal surfaces and is found in secretions such as
saliva, tears, respiratory secretions, and breast milk.
7. Which immune cell is most directly responsible for destroying virus-infected
cells and tumor cells without prior sensitization?
A. Natural killer cell
B. B lymphocyte
C. Plasma cell
D. Basophil
Answer: A. Natural killer cell
Rationale: Natural killer cells can recognize and destroy certain infected or
abnormal cells as part of innate immunity.
8. A patient has an elevated eosinophil count. Which condition should the
nurse consider?
A. Severe blood loss
B. Parasitic infection or allergy
C. Bacterial pneumonia only
D. Iron-deficiency anemia
Answer: B. Parasitic infection or allergy
Rationale: Eosinophils are commonly increased with allergic disorders and
parasitic infections.
, 9. Which cells are responsible for initiating and coordinating many adaptive
immune responses?
A. Platelets
B. Red blood cells
C. Lymphocytes
D. Erythrocytes
Answer: C. Lymphocytes
Rationale: B and T lymphocytes are central components of adaptive immunity
and provide antigen-specific immune responses.
10.Which T lymphocyte primarily coordinates immune responses by releasing
cytokines?
A. Helper T cell
B. Cytotoxic T cell
C. Memory B cell
D. Plasma cell
Answer: A. Helper T cell
Rationale: Helper T cells release cytokines that activate and coordinate other
immune cells.
11.Which T cell directly destroys infected or abnormal body cells?
A. Helper T cell
B. Cytotoxic T cell
C. Regulatory T cell
D. Memory T cell
Answer: B. Cytotoxic T cell
Rationale: Cytotoxic T cells recognize specific antigen-presenting target cells and
induce their destruction.
12.Which organ is the primary site of T-cell maturation?
Nursing 354 Immune System Nursing
Exam Questions And Correct Answers
(Verified Answers) Plus Rationales 2026
Q&A Instant Download Pdf
___________________________________________________________________
1. Which component of the immune system provides the body's first line of
defense against pathogens?
A. Antibodies
B. Skin and mucous membranes
C. T lymphocytes
D. B lymphocytes
Answer: B. Skin and mucous membranes
Rationale: Skin and mucous membranes form physical and chemical barriers
that prevent many pathogens from entering the body.
2. Which type of immunity develops after a person receives a vaccine?
A. Natural passive immunity
B. Artificial passive immunity
C. Artificial active immunity
D. Natural active immunity
Answer: C. Artificial active immunity
,Rationale: Vaccination exposes the immune system to antigens, stimulating an
active immune response and formation of memory cells.
3. Which white blood cell is primarily responsible for producing antibodies?
A. Neutrophil
B. B lymphocyte
C. Natural killer cell
D. Monocyte
Answer: B. B lymphocyte
Rationale: B lymphocytes differentiate into plasma cells that produce antibodies
against specific antigens.
4. Which immunoglobulin is most abundant in the blood and provides long-
term systemic protection?
A. IgA
B. IgE
C. IgM
D. IgG
Answer: D. IgG
Rationale: IgG is the most abundant immunoglobulin in serum and provides
significant protection against many bacterial and viral infections.
5. Which immunoglobulin is primarily associated with allergic reactions?
A. IgE
B. IgG
C. IgA
D. IgM
Answer: A. IgE
Rationale: IgE binds to mast cells and basophils and plays a major role in
immediate hypersensitivity and allergic reactions.
, 6. Which immunoglobulin is found primarily in secretions such as saliva, tears,
and breast milk?
A. IgM
B. IgA
C. IgG
D. IgE
Answer: B. IgA
Rationale: IgA protects mucosal surfaces and is found in secretions such as
saliva, tears, respiratory secretions, and breast milk.
7. Which immune cell is most directly responsible for destroying virus-infected
cells and tumor cells without prior sensitization?
A. Natural killer cell
B. B lymphocyte
C. Plasma cell
D. Basophil
Answer: A. Natural killer cell
Rationale: Natural killer cells can recognize and destroy certain infected or
abnormal cells as part of innate immunity.
8. A patient has an elevated eosinophil count. Which condition should the
nurse consider?
A. Severe blood loss
B. Parasitic infection or allergy
C. Bacterial pneumonia only
D. Iron-deficiency anemia
Answer: B. Parasitic infection or allergy
Rationale: Eosinophils are commonly increased with allergic disorders and
parasitic infections.
, 9. Which cells are responsible for initiating and coordinating many adaptive
immune responses?
A. Platelets
B. Red blood cells
C. Lymphocytes
D. Erythrocytes
Answer: C. Lymphocytes
Rationale: B and T lymphocytes are central components of adaptive immunity
and provide antigen-specific immune responses.
10.Which T lymphocyte primarily coordinates immune responses by releasing
cytokines?
A. Helper T cell
B. Cytotoxic T cell
C. Memory B cell
D. Plasma cell
Answer: A. Helper T cell
Rationale: Helper T cells release cytokines that activate and coordinate other
immune cells.
11.Which T cell directly destroys infected or abnormal body cells?
A. Helper T cell
B. Cytotoxic T cell
C. Regulatory T cell
D. Memory T cell
Answer: B. Cytotoxic T cell
Rationale: Cytotoxic T cells recognize specific antigen-presenting target cells and
induce their destruction.
12.Which organ is the primary site of T-cell maturation?
