WGU COMPREHENSIVE NURSING 2026
ACTUAL PRACTICE EXAM QUESTIONS
AND VERIFIED CORRECT ANSWERS
GRADED A+
A client receives a prescription for ciprofloxacin 400 mg intravenously (IV) every
12 hours to be infused over an hour. The IV bag contains ciprofloxacin 400 mg in
dextrose 5% in water (DW) 200 mL. The nurse should program the infusion pump
to deliver how many mL/hr? (Enter numerical value only.)
200
A client with anemia secondary to chronic kidney disease (CKD) started a
prescription for epoetin alfa two months ago. Which client finding best indicates
that the medication is effective?
Reference Range:
Hemoglobin (Hgb) [14 to 18 g/dL (8.7 to 11.2 mmol/L)
A. Reports of increased energy levels and decreased fatigue.
B. Takes concurrent iron therapy without adverse effects.
C. Food diary shows increased consumption of iron-rich foods.
D. Hemoglobin level
D. Hemoglobin level
The nurse administers naloxone to a client with opioid-induced respiratory
depression. One hour later, nursing assessment reveals that the client has a
,respiratory rate of 4 breaths/minute, oxygen saturation of 75%, and is unable to be
aroused. Which action should the nurse implement?
A. Administer a second dose of naloxone.
B. Determine Glasgow Coma Scale score.
C. Initiate cardiopulmonary resuscitation (CPR)
D. Prepare to assist with chest tube insertion.
A. Administer a second dose of naloxone.
The healthcare provider prescribes propylthiouracil (PTU) and Lugol's solution, a
strong iodine solution, for a client with hyperthyroidism. How should the nurse
schedule the administration of these medications?
A. Offer both drugs together with a meal.
B. Schedule both medications at bedtime.
C. Give parental dose once every 24 hours.
D. Administer iodine one hour before PTU.
D. Administer iodine one hour before PTU.
The nurse is assessing a client who was recently diagnosed with Parkinson's
disease and is taking carbidopa-levodopa. The client is concerned that the
medication is not working. Which intervention should the nurse implement first?
A. Ask if the dient's morning voids are dark colored.
B. Explore what the client means by the drug "is not working."
,C. Evaluate the client for signs of dyskinesia.
D. Determine if the client is taking the medication before meals.
B. Explore what the client means by the drug "is not working."
A client who is taking dextroamphetamine-amphetamine extended-release tablets
for attention deficit hyperactivity disorder (ADHD), reports about having difficulty
sleeping at night. Which assessment is most important for the nurse to obtain?
A. Determine what time the dose is taken.
B. Determine daily caffeine intake.
C. Ask about the client's bedtime routine.
D. Inquire about perceived anxiety.
. Determine what time the dose is taken.
A client receives a prescription for allopurinol. Which information provided by the
client requires additional instruction by the nurse?
A. Avoid taking on an empty stomach.
B. Reduce caffeine and acidic intake.
C. Consume 2 liters of water daily.
D. Double the dose if a dose is missed.
D. Double the dose if a dose is missed.
, Which nursing intervention has priority when initiating a continuous epidural
infusion with an opioid analgesic?
A. Apply a pulse oximeter to the client per protocol.
B. Administer a stool softener per PRN protocol.
C. Insert an indwelling urinary catheter per protocol.
D. Administer an antiemetic per PRN prescription.
A. Apply a pulse oximeter to the client per protocol
A client is receiving orlistat as part of a weight management program. Which
ongoing assessment should be included in the plan of care to determine the
effectiveness of the medication?
A. Serum protein levels.
B. Body mass index (BMI).
C. Daily calorie count.
D. Depression screening.
B. Body mass index (BMI).
The nurse is teaching a client who has been diagnosed with human
immunodeficiency virus (HIV) about the antiretroviral medication regimen. Which
statement provided by the client requires additional instruction by the nurse?
A. HIV infection is not cured by the antiretroviral regimen.
B. The viral load can be decreased to an undetectable level.
ACTUAL PRACTICE EXAM QUESTIONS
AND VERIFIED CORRECT ANSWERS
GRADED A+
A client receives a prescription for ciprofloxacin 400 mg intravenously (IV) every
12 hours to be infused over an hour. The IV bag contains ciprofloxacin 400 mg in
dextrose 5% in water (DW) 200 mL. The nurse should program the infusion pump
to deliver how many mL/hr? (Enter numerical value only.)
200
A client with anemia secondary to chronic kidney disease (CKD) started a
prescription for epoetin alfa two months ago. Which client finding best indicates
that the medication is effective?
Reference Range:
Hemoglobin (Hgb) [14 to 18 g/dL (8.7 to 11.2 mmol/L)
A. Reports of increased energy levels and decreased fatigue.
B. Takes concurrent iron therapy without adverse effects.
C. Food diary shows increased consumption of iron-rich foods.
D. Hemoglobin level
D. Hemoglobin level
The nurse administers naloxone to a client with opioid-induced respiratory
depression. One hour later, nursing assessment reveals that the client has a
,respiratory rate of 4 breaths/minute, oxygen saturation of 75%, and is unable to be
aroused. Which action should the nurse implement?
A. Administer a second dose of naloxone.
B. Determine Glasgow Coma Scale score.
C. Initiate cardiopulmonary resuscitation (CPR)
D. Prepare to assist with chest tube insertion.
A. Administer a second dose of naloxone.
The healthcare provider prescribes propylthiouracil (PTU) and Lugol's solution, a
strong iodine solution, for a client with hyperthyroidism. How should the nurse
schedule the administration of these medications?
A. Offer both drugs together with a meal.
B. Schedule both medications at bedtime.
C. Give parental dose once every 24 hours.
D. Administer iodine one hour before PTU.
D. Administer iodine one hour before PTU.
The nurse is assessing a client who was recently diagnosed with Parkinson's
disease and is taking carbidopa-levodopa. The client is concerned that the
medication is not working. Which intervention should the nurse implement first?
A. Ask if the dient's morning voids are dark colored.
B. Explore what the client means by the drug "is not working."
,C. Evaluate the client for signs of dyskinesia.
D. Determine if the client is taking the medication before meals.
B. Explore what the client means by the drug "is not working."
A client who is taking dextroamphetamine-amphetamine extended-release tablets
for attention deficit hyperactivity disorder (ADHD), reports about having difficulty
sleeping at night. Which assessment is most important for the nurse to obtain?
A. Determine what time the dose is taken.
B. Determine daily caffeine intake.
C. Ask about the client's bedtime routine.
D. Inquire about perceived anxiety.
. Determine what time the dose is taken.
A client receives a prescription for allopurinol. Which information provided by the
client requires additional instruction by the nurse?
A. Avoid taking on an empty stomach.
B. Reduce caffeine and acidic intake.
C. Consume 2 liters of water daily.
D. Double the dose if a dose is missed.
D. Double the dose if a dose is missed.
, Which nursing intervention has priority when initiating a continuous epidural
infusion with an opioid analgesic?
A. Apply a pulse oximeter to the client per protocol.
B. Administer a stool softener per PRN protocol.
C. Insert an indwelling urinary catheter per protocol.
D. Administer an antiemetic per PRN prescription.
A. Apply a pulse oximeter to the client per protocol
A client is receiving orlistat as part of a weight management program. Which
ongoing assessment should be included in the plan of care to determine the
effectiveness of the medication?
A. Serum protein levels.
B. Body mass index (BMI).
C. Daily calorie count.
D. Depression screening.
B. Body mass index (BMI).
The nurse is teaching a client who has been diagnosed with human
immunodeficiency virus (HIV) about the antiretroviral medication regimen. Which
statement provided by the client requires additional instruction by the nurse?
A. HIV infection is not cured by the antiretroviral regimen.
B. The viral load can be decreased to an undetectable level.
