MAMMALIAN GENETICS BCH5413 EXAM 1 UPDATED
ACTUAL QUESTIONS AND CORRECT ANSWERS
Question:
1. Because the DNA was not destroyed, meaning that the
pathogenic strain is still able to be taken up by the
healthy DNA, causing death
Answer:
Why does the mouse die if the researcher mixes the dead pathogenic strain with
the live non-pathogenic strain bacteria and then inject it into the mouse?
Question:
2. When the DNA was completely destroyed; the S strain
was no longer able to be pathogenic without its DNA
Answer:
What was the only scenario in which the mouse lives? Why?
Question:
3. How many angstroms is the distance between stacked base pairs in DNA?
Answer:
3.4 A
Question:
4. What year was the structure of DNA discovered?
Answer:
1953
Question:
5. They did x-ray crystallography to discover the "X" helix
pattern of DNA
Answer:
How did Wilkins and Franklin contribute to the discovery of DNA's structure?
Question:
6. A phosphate, a 5-C sugar, and a nitrogenous base
Answer:
What are the 3 components of a nucleotide?
,Question:
7. They made a model of the structure of helical DNA using
others' previous research
Answer:
How did Watson and Crick contribute to the discovery of DNA's structure?
Question:
8. A nitrogenous base (A, G, T, or C)
Answer:
What is attached to the 1' C in DNA's 5-C sugar?
Question:
9. Which bases are the purines?
Answer:
A and G
Question:
10. Which bases are the pyrimidines?
Answer:
C, T, and U
Question:
11. True
Answer:
T/F: Purines have a double-ring structure while pyrimidines have a single-ring
structure.
Question:
12. An -H group (if DNA) or an -OH group (if RNA)
Answer:
What is attached to the 2' C in DNA's 5-C sugar?
Question:
13. An -OH group (will interact with the phosphate on the 5'
C of the next nucleotide)
Answer:
What is attached to the 3' C in DNA's 5-C sugar?
, Question:
14. It completes the ring structure (connects the 5' C and 3'
C to the oxygen in the ring)
Answer:
What is attached to the 4' C in DNA's 5-C sugar?
Question:
15. A phosphate group (will interact with the -OH group on
the 3' C of the next nucleotide)
Answer:
What is attached to the 5' C in DNA's 5-C sugar?
Question:
16. The phosphate group losing an oxygen in water
Answer:
What gives DNA its (-) charge?
Question:
17. It connects from phosphate group -> -OH group ->
phosphate group, etc. (never backwards), which allows
the nitrogenous bases to hydrogen bond
Answer:
Why does DNA have directionality?
Question:
18. One single-strand of DNA is 5' -> 3' and the other strand
it connects to is 3' -> 5' (the strands do not connect in the
same direction to form dsDNA)
Answer:
What does it mean that DNA is antiparallel?
Question:
19. That DNA replication is semiconservative (the parent
strand unzips to allow for synthesis of a new strand)
Answer:
What does the Meselson and Stahl experiment (1958) confirm?
ACTUAL QUESTIONS AND CORRECT ANSWERS
Question:
1. Because the DNA was not destroyed, meaning that the
pathogenic strain is still able to be taken up by the
healthy DNA, causing death
Answer:
Why does the mouse die if the researcher mixes the dead pathogenic strain with
the live non-pathogenic strain bacteria and then inject it into the mouse?
Question:
2. When the DNA was completely destroyed; the S strain
was no longer able to be pathogenic without its DNA
Answer:
What was the only scenario in which the mouse lives? Why?
Question:
3. How many angstroms is the distance between stacked base pairs in DNA?
Answer:
3.4 A
Question:
4. What year was the structure of DNA discovered?
Answer:
1953
Question:
5. They did x-ray crystallography to discover the "X" helix
pattern of DNA
Answer:
How did Wilkins and Franklin contribute to the discovery of DNA's structure?
Question:
6. A phosphate, a 5-C sugar, and a nitrogenous base
Answer:
What are the 3 components of a nucleotide?
,Question:
7. They made a model of the structure of helical DNA using
others' previous research
Answer:
How did Watson and Crick contribute to the discovery of DNA's structure?
Question:
8. A nitrogenous base (A, G, T, or C)
Answer:
What is attached to the 1' C in DNA's 5-C sugar?
Question:
9. Which bases are the purines?
Answer:
A and G
Question:
10. Which bases are the pyrimidines?
Answer:
C, T, and U
Question:
11. True
Answer:
T/F: Purines have a double-ring structure while pyrimidines have a single-ring
structure.
Question:
12. An -H group (if DNA) or an -OH group (if RNA)
Answer:
What is attached to the 2' C in DNA's 5-C sugar?
Question:
13. An -OH group (will interact with the phosphate on the 5'
C of the next nucleotide)
Answer:
What is attached to the 3' C in DNA's 5-C sugar?
, Question:
14. It completes the ring structure (connects the 5' C and 3'
C to the oxygen in the ring)
Answer:
What is attached to the 4' C in DNA's 5-C sugar?
Question:
15. A phosphate group (will interact with the -OH group on
the 3' C of the next nucleotide)
Answer:
What is attached to the 5' C in DNA's 5-C sugar?
Question:
16. The phosphate group losing an oxygen in water
Answer:
What gives DNA its (-) charge?
Question:
17. It connects from phosphate group -> -OH group ->
phosphate group, etc. (never backwards), which allows
the nitrogenous bases to hydrogen bond
Answer:
Why does DNA have directionality?
Question:
18. One single-strand of DNA is 5' -> 3' and the other strand
it connects to is 3' -> 5' (the strands do not connect in the
same direction to form dsDNA)
Answer:
What does it mean that DNA is antiparallel?
Question:
19. That DNA replication is semiconservative (the parent
strand unzips to allow for synthesis of a new strand)
Answer:
What does the Meselson and Stahl experiment (1958) confirm?
