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Samenvatting Embryologie & Genetica | Gametogenese | VIVES | 2024/25

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Collegeanotities voor Embryologie en Genetica aan Katholieke Hogeschool VIVES, met focus op Hoofdstuk 4 Gametogenese onder leiding van Dr. Maarten Biesbrouck. De stof behandelt de vorming van geslachtscellen (oögenese en spermatogenese), kiembaancellen, non-disjunctie meiose, en het maternale leeftijdseffect op chromosomale afwijkingen zoals trisomie 21. Uitstekend materiaal voor examenvoorbereiding in de Bachelor Vroedkunde, met duidelijke uitleg van essentiële concepten en grafieken over risicofactoren.

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EMBRYOLOGIE
& GENETICA
V3C404




1
Dr. Maarten Biesbrouck


,H4 GAMETOGENESE

, GAMETOGENESE

• Vorming van (rijpe) geslachtscellen (gameten) vanuit primordiale kiemcellen

= toepassing van mitose en meiose


o Oögenese bij de vrouw: vorming van eicellen
o Spermatogenese bij de man: vorming van zaadcellen
H4 GAMETOGENESE




3
! à essentiële kennis voor het begrijpen van hoofdstuk 14

, KIEMBAANCELLEN

= primordiale kiemcellen, stamcellen, germ line cells
= de cellen waaruit gameten worden gevormd


(!) Foutjes (of therapeutische aanpassingen) in
kiembaancellen worden doorgegeven aan het
nageslacht
H4 GAMETOGENESE




”the advent of human-germline editing
brings urgency to ethical discussions”
4
(Jennifer Doudna, Nature, 2015)
Cfr. 20.2.2

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