Test Bank for Abrams’ Clinical
Drug Therapy Rationales For
Nursing And Pharmacy Practice
Questions and Correct Answers
A woman with a long history of clot formation is scheduled for bowel resection due to
colorectal
cancer. What anticoagulant agent will be administered prophylactically?
A. Acetylsalicylic acid
B. Dalteparin
C. Warfarin
D. Streptokinase
B. Dalteparin
A man has been administered heparin to prevent thromboembolism development status
postmyocardial infarction. The man develops heparin-induced thrombocytopenia. Which
medication will be administered?
A. Argatroban 9
B. Vitamin K
C. Calcium gluconate
D. Aminocaproic acid
A. Argatroban 9
A man is receiving low-molecular-weight heparin (LMWH) to prevent thromboembolic
complications. The nursing student asks the instructor the reason why this treatment is
given instead of heparin. What is the instructor's best explanation of the rationale for
LMWH over heparin?
A. "LMWH is associated with less thrombocytopenia than standard heparin."
B. "LWMH is associated with stronger anticoagulant effects than standard heparin."
C. "LWMH is given to clients who have a history of blood dyscrasia."
D. "LWMH is more effective than standard heparin for clients with hypertension."
A. "LMWH is associated with less thrombocytopenia than standard heparin."
A client who is receiving warfarin has blood in the urinary drainage bag. What
medication
will likely be prescribed by the health care provider?
A. Aminocaproic acid
B. Platelets
C. Protamine sulfate
D. Vitamin K
D. Vitamin K
A client has developed the formation of clots and has bruising. It is determined that
there
is a depletion of the client's coagulation factors and widespread bleeding. Which
medication will be administered?
,A. Aminocaproic acid
B. Heparin
C. Warfarin
D. Protamine sulfate
B. Heparin
A client is admitted with thrombophlebitis and sent home on enoxaparin therapy. Which
statement indicates a good understanding of why enoxaparin is being administered?
A. Enoxaparin inhibits the formation of additional clots.
B. Enoxaparin eliminates certain clotting factors.
C. Enoxaparin decreases the viscosity of blood.
D. Enoxaparin will dissolve the clots.
A. Enoxaparin inhibits the formation of additional clots.
A client is being discharged from the hospital with warfarin to be taken at home. Which
food should the client be instructed to avoid?
A. eggs
B. dairy products
C. citrus fruits
D. spinach
D. spinach
A patient is discharged from the hospital with a prescription for warfarin. Which
statement
by the client indicates successful client teaching?
A. "I'll stop taking vitamin C supplements."
B. "I will avoid ginseng and St. John's wort."
C. "I will eat plenty of spinach or broccoli daily."
D. "I will discontinue my other medications."
B. "I will avoid ginseng and St. John's wort."
A client is being administered heparin IV and has been started on warfarin. The client
asks
the nurse why both medications have been prescribed. What is the
nurse's most accurate
response?
A. "A low dose of both drugs carries fewer risks for adverse effects than a larger dose
of one drug."
B. "You will need both warfarin and heparin for several weeks until you're cleared by
your health care provider."
C. "Warfarin takes 3-5 days to develop anticoagulant effects so you still need
heparin."
D. "Warfarin cannot be given without heparin due to the amount of anticoagulation
you need."
C. "Warfarin takes 3-5 days to develop anticoagulant effects so you still need
heparin."
A client is prescribed eptifibatide, which inhibits platelet aggregation by preventing
activation of GP IIb/IIIa receptors on the platelet surface and the subsequent binding of
fibrinogen and von Willebrand factor to platelets. Which syndrome is treated with
eptifibatide?
,A. Blocked carotid arteries
B. Intermittent claudication
C. Hypertension
D. Unstable angina
D. Unstable angina
A client is receiving IV heparin every 6 hours. An activated partial thromboplastin time
(aPTT) is drawn 1 hour before the 08:00 am dose. The PTT is 92 seconds. What is the
most appropriate action by the nurse?
A. Give the next two doses at the same time.
B. Give the dose and chart the client response.
C. Check the client's vital signs and give the dose.
D. Hold the dose and the call the aPTT result to the health care provider's attention.
D. Hold the dose and the call the aPTT result to the health care provider's attention.
A client is taking warfarin to prevent clot formation related to atrial fibrillation. How are
the effects of the warfarin monitored?
A. RBC
B. aPTT
C. PT and INR
D. Platelet count
C. PT and INR
A client taking warfarin after open heart surgery reports pain in both knees that began
this
week. The nurse notes bruises on both knees. Based on the effects of the medications
and
the report of pain, what should the nurse suspect is the cause of the pain?
A. Joint thrombosis
B. Torn medial meniscus
C. Degenerative joint disease caused by her medication
D. Bleeding
D. Bleeding
A man who is recovering in hospital from a bilateral mastectomy has developed minor
bleeding at one of the incision sites. During the process of clot formation, plasminogen
will become part of a clot by which means?
A. By binding with fibrin
B. By binding with platelets
C. By activating plasmin
D. By activating factor VII
A. By binding with fibrin
A 60-year-old client has been diagnosed with coronary artery disease and begun
antiplatelet therapy. The client has asked the nurse why a "blood thinner like warfarin"
hasn't been prescribed. What is the most likely rationale for the clinician's use of an
antiplatelet agent rather than an anticoagulant?
A. Antiplatelet agents do not require the client to undergo frequent blood work;
anticoagulants require constant blood work to ensure safety.
B. Antiplatelet agents are more effective against arterial thrombosis; anticoagulants
are more effective against venous thrombosis.
, C. Antiplatelet agents are most effective in large vessels; anticoagulants are most
effective in the small vessels of the peripheral circulation.
D. Antiplatelet agents have fewer adverse effects than anticoagulants.
B. Antiplatelet agents are more effective against arterial thrombosis; anticoagulants
are more effective against venous thrombosis.
A nurse at a long-term care facility is conducting a medication reconciliation for a client
who has just moved into the facility. The client is currently taking clopidogrel. The nurse
is most justified suspecting that this client has a history of what condition?
A. Hemorrhagic cerebrovascular accident
B. Hemophilia A
C. Idiopathic thrombocytopenic purpura (ITP)
D. Myocardial infarction
D. Myocardial infarction
A 79-year-old client has been brought to the emergency department by ambulance with
signs and symptoms of ischemic stroke. The care team would consider the immediate
(STAT) administration of what drug?
A. Low-molecular-weight heparin
B. Vitamin K
C. clopidogrel
D. Alteplase
D. Alteplase
A 50-year-old client has undergone a bunionectomy and has been admitted to the
postsurgical unit. What aspect of the client's medical history would contraindicate the
use
of heparin for deep vein thrombosis (DVT) prophylaxis?
A. Obesity
B. Diagnosis of ulcerative colitis
C. Myocardial infarction (MI) 18 months ago.
D. Diagnosis of type 2 diabetes mellitus
B. Diagnosis of ulcerative colitis
A client with atrial fibrillation was prescribed 20 mg rivaroxaban daily, beginning 2
weeks
ago. Prior to administering the scheduled dose, the nurse will perform which action?
A. Ensure the client has recently eaten.
B. Confirm patency of the client's IV access.
C. Confirm the client's most recent international normalized ratio (INR).
D. Confirm the client's most recent D-dimer.
A. Ensure the client has recently eaten.
A client with atrial fibrillation has been prescribed dabigatran etexilate. When monitoring
for adverse effects, the nurse should prioritize which assessment?
A. assessment for bleeding
B. heart rate and rhythm
C. monitoring for anaphylaxis
D. observing for hypercoagulable state
A. assessment for bleeding
Drug Therapy Rationales For
Nursing And Pharmacy Practice
Questions and Correct Answers
A woman with a long history of clot formation is scheduled for bowel resection due to
colorectal
cancer. What anticoagulant agent will be administered prophylactically?
A. Acetylsalicylic acid
B. Dalteparin
C. Warfarin
D. Streptokinase
B. Dalteparin
A man has been administered heparin to prevent thromboembolism development status
postmyocardial infarction. The man develops heparin-induced thrombocytopenia. Which
medication will be administered?
A. Argatroban 9
B. Vitamin K
C. Calcium gluconate
D. Aminocaproic acid
A. Argatroban 9
A man is receiving low-molecular-weight heparin (LMWH) to prevent thromboembolic
complications. The nursing student asks the instructor the reason why this treatment is
given instead of heparin. What is the instructor's best explanation of the rationale for
LMWH over heparin?
A. "LMWH is associated with less thrombocytopenia than standard heparin."
B. "LWMH is associated with stronger anticoagulant effects than standard heparin."
C. "LWMH is given to clients who have a history of blood dyscrasia."
D. "LWMH is more effective than standard heparin for clients with hypertension."
A. "LMWH is associated with less thrombocytopenia than standard heparin."
A client who is receiving warfarin has blood in the urinary drainage bag. What
medication
will likely be prescribed by the health care provider?
A. Aminocaproic acid
B. Platelets
C. Protamine sulfate
D. Vitamin K
D. Vitamin K
A client has developed the formation of clots and has bruising. It is determined that
there
is a depletion of the client's coagulation factors and widespread bleeding. Which
medication will be administered?
,A. Aminocaproic acid
B. Heparin
C. Warfarin
D. Protamine sulfate
B. Heparin
A client is admitted with thrombophlebitis and sent home on enoxaparin therapy. Which
statement indicates a good understanding of why enoxaparin is being administered?
A. Enoxaparin inhibits the formation of additional clots.
B. Enoxaparin eliminates certain clotting factors.
C. Enoxaparin decreases the viscosity of blood.
D. Enoxaparin will dissolve the clots.
A. Enoxaparin inhibits the formation of additional clots.
A client is being discharged from the hospital with warfarin to be taken at home. Which
food should the client be instructed to avoid?
A. eggs
B. dairy products
C. citrus fruits
D. spinach
D. spinach
A patient is discharged from the hospital with a prescription for warfarin. Which
statement
by the client indicates successful client teaching?
A. "I'll stop taking vitamin C supplements."
B. "I will avoid ginseng and St. John's wort."
C. "I will eat plenty of spinach or broccoli daily."
D. "I will discontinue my other medications."
B. "I will avoid ginseng and St. John's wort."
A client is being administered heparin IV and has been started on warfarin. The client
asks
the nurse why both medications have been prescribed. What is the
nurse's most accurate
response?
A. "A low dose of both drugs carries fewer risks for adverse effects than a larger dose
of one drug."
B. "You will need both warfarin and heparin for several weeks until you're cleared by
your health care provider."
C. "Warfarin takes 3-5 days to develop anticoagulant effects so you still need
heparin."
D. "Warfarin cannot be given without heparin due to the amount of anticoagulation
you need."
C. "Warfarin takes 3-5 days to develop anticoagulant effects so you still need
heparin."
A client is prescribed eptifibatide, which inhibits platelet aggregation by preventing
activation of GP IIb/IIIa receptors on the platelet surface and the subsequent binding of
fibrinogen and von Willebrand factor to platelets. Which syndrome is treated with
eptifibatide?
,A. Blocked carotid arteries
B. Intermittent claudication
C. Hypertension
D. Unstable angina
D. Unstable angina
A client is receiving IV heparin every 6 hours. An activated partial thromboplastin time
(aPTT) is drawn 1 hour before the 08:00 am dose. The PTT is 92 seconds. What is the
most appropriate action by the nurse?
A. Give the next two doses at the same time.
B. Give the dose and chart the client response.
C. Check the client's vital signs and give the dose.
D. Hold the dose and the call the aPTT result to the health care provider's attention.
D. Hold the dose and the call the aPTT result to the health care provider's attention.
A client is taking warfarin to prevent clot formation related to atrial fibrillation. How are
the effects of the warfarin monitored?
A. RBC
B. aPTT
C. PT and INR
D. Platelet count
C. PT and INR
A client taking warfarin after open heart surgery reports pain in both knees that began
this
week. The nurse notes bruises on both knees. Based on the effects of the medications
and
the report of pain, what should the nurse suspect is the cause of the pain?
A. Joint thrombosis
B. Torn medial meniscus
C. Degenerative joint disease caused by her medication
D. Bleeding
D. Bleeding
A man who is recovering in hospital from a bilateral mastectomy has developed minor
bleeding at one of the incision sites. During the process of clot formation, plasminogen
will become part of a clot by which means?
A. By binding with fibrin
B. By binding with platelets
C. By activating plasmin
D. By activating factor VII
A. By binding with fibrin
A 60-year-old client has been diagnosed with coronary artery disease and begun
antiplatelet therapy. The client has asked the nurse why a "blood thinner like warfarin"
hasn't been prescribed. What is the most likely rationale for the clinician's use of an
antiplatelet agent rather than an anticoagulant?
A. Antiplatelet agents do not require the client to undergo frequent blood work;
anticoagulants require constant blood work to ensure safety.
B. Antiplatelet agents are more effective against arterial thrombosis; anticoagulants
are more effective against venous thrombosis.
, C. Antiplatelet agents are most effective in large vessels; anticoagulants are most
effective in the small vessels of the peripheral circulation.
D. Antiplatelet agents have fewer adverse effects than anticoagulants.
B. Antiplatelet agents are more effective against arterial thrombosis; anticoagulants
are more effective against venous thrombosis.
A nurse at a long-term care facility is conducting a medication reconciliation for a client
who has just moved into the facility. The client is currently taking clopidogrel. The nurse
is most justified suspecting that this client has a history of what condition?
A. Hemorrhagic cerebrovascular accident
B. Hemophilia A
C. Idiopathic thrombocytopenic purpura (ITP)
D. Myocardial infarction
D. Myocardial infarction
A 79-year-old client has been brought to the emergency department by ambulance with
signs and symptoms of ischemic stroke. The care team would consider the immediate
(STAT) administration of what drug?
A. Low-molecular-weight heparin
B. Vitamin K
C. clopidogrel
D. Alteplase
D. Alteplase
A 50-year-old client has undergone a bunionectomy and has been admitted to the
postsurgical unit. What aspect of the client's medical history would contraindicate the
use
of heparin for deep vein thrombosis (DVT) prophylaxis?
A. Obesity
B. Diagnosis of ulcerative colitis
C. Myocardial infarction (MI) 18 months ago.
D. Diagnosis of type 2 diabetes mellitus
B. Diagnosis of ulcerative colitis
A client with atrial fibrillation was prescribed 20 mg rivaroxaban daily, beginning 2
weeks
ago. Prior to administering the scheduled dose, the nurse will perform which action?
A. Ensure the client has recently eaten.
B. Confirm patency of the client's IV access.
C. Confirm the client's most recent international normalized ratio (INR).
D. Confirm the client's most recent D-dimer.
A. Ensure the client has recently eaten.
A client with atrial fibrillation has been prescribed dabigatran etexilate. When monitoring
for adverse effects, the nurse should prioritize which assessment?
A. assessment for bleeding
B. heart rate and rhythm
C. monitoring for anaphylaxis
D. observing for hypercoagulable state
A. assessment for bleeding
