ANCC FAMILY NURSE PRACTITIONER
(FNP) COMPREHENSIVE FINAL EXAM
PREP (2026/2027) QUESTIONS AND
ANSWERS
1. A 68-year-old male presents with a harsh, crescendo-decrescendo systolic murmur heard
best at the second right intercostal space, radiating to the carotids. He reports recent
episodes of exertional syncope. What is the most likely diagnosis?
A. Mitral Regurgitation
B. Aortic Regurgitation
C. Aortic Stenosis
D. Mitral Stenosis
Answer: C
Conceptual Explanation: Aortic stenosis is characterized by a harsh systolic crescendo-
decrescendo murmur at the right upper sternal border that radiates to the carotids. The
classic triad of symptoms includes chest pain, heart failure, and syncope.
,2. Which ethical principle is defined as the duty to ‘do no harm’ to the patient?
A. Beneficence
B. Non-maleficence
C. Autonomy
D. Justice
Answer: B
Conceptual Explanation: Non-maleficence is the ethical obligation to protect the patient
from harm. Beneficence is the duty to do good, while Justice refers to fairness in the
distribution of resources.
3. A 45-year-old female patient with a history of Type 2 Diabetes presents with a new onset
of microalbuminuria. Which class of medication should be initiated to provide renal
protection?
A. ACE Inhibitors
B. Calcium Channel Blockers
C. Thiazide Diuretics
D. Beta-Blockers
Answer: A
, Conceptual Explanation: ACE inhibitors (or ARBs) are recommended for diabetic patients
with microalbuminuria because they lower intraglomerular pressure and provide a
renoprotective effect.
4. An 8-year-old child presents with a ‘slapped-cheek’ rash and a lacy, reticular rash on the
trunk and arms. Which pathogen is responsible for this condition?
A. Coxsackievirus
B. Human Herpesvirus 6
C. Varicella Zoster
D. Parvovirus B19
Answer: D
Conceptual Explanation: Parvovirus B19 causes Erythema Infectiosum (Fifth Disease),
typically presenting with the classic ‘slapped-cheek’ appearance followed by a lacy
maculopapular rash.
5. A patient’s lab results show: HBsAg positive, HBeAg positive, Anti-HBc IgM positive, and
Anti-HBs negative. What is the clinical interpretation?
A. Acute Hepatitis B infection
B. Chronic Hepatitis B infection
C. Immunity due to vaccination
D. Recovery from prior infection
(FNP) COMPREHENSIVE FINAL EXAM
PREP (2026/2027) QUESTIONS AND
ANSWERS
1. A 68-year-old male presents with a harsh, crescendo-decrescendo systolic murmur heard
best at the second right intercostal space, radiating to the carotids. He reports recent
episodes of exertional syncope. What is the most likely diagnosis?
A. Mitral Regurgitation
B. Aortic Regurgitation
C. Aortic Stenosis
D. Mitral Stenosis
Answer: C
Conceptual Explanation: Aortic stenosis is characterized by a harsh systolic crescendo-
decrescendo murmur at the right upper sternal border that radiates to the carotids. The
classic triad of symptoms includes chest pain, heart failure, and syncope.
,2. Which ethical principle is defined as the duty to ‘do no harm’ to the patient?
A. Beneficence
B. Non-maleficence
C. Autonomy
D. Justice
Answer: B
Conceptual Explanation: Non-maleficence is the ethical obligation to protect the patient
from harm. Beneficence is the duty to do good, while Justice refers to fairness in the
distribution of resources.
3. A 45-year-old female patient with a history of Type 2 Diabetes presents with a new onset
of microalbuminuria. Which class of medication should be initiated to provide renal
protection?
A. ACE Inhibitors
B. Calcium Channel Blockers
C. Thiazide Diuretics
D. Beta-Blockers
Answer: A
, Conceptual Explanation: ACE inhibitors (or ARBs) are recommended for diabetic patients
with microalbuminuria because they lower intraglomerular pressure and provide a
renoprotective effect.
4. An 8-year-old child presents with a ‘slapped-cheek’ rash and a lacy, reticular rash on the
trunk and arms. Which pathogen is responsible for this condition?
A. Coxsackievirus
B. Human Herpesvirus 6
C. Varicella Zoster
D. Parvovirus B19
Answer: D
Conceptual Explanation: Parvovirus B19 causes Erythema Infectiosum (Fifth Disease),
typically presenting with the classic ‘slapped-cheek’ appearance followed by a lacy
maculopapular rash.
5. A patient’s lab results show: HBsAg positive, HBeAg positive, Anti-HBc IgM positive, and
Anti-HBs negative. What is the clinical interpretation?
A. Acute Hepatitis B infection
B. Chronic Hepatitis B infection
C. Immunity due to vaccination
D. Recovery from prior infection
