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Phar 100 Midterm (Modules 1-3) Questions With Correct Answers..

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PHAR 100 MIDTERM (MODULES 1-3) QUESTIONS WITH CORRECT ANSWERS

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What type of drugs enhance GABA receptor function in the brain?


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CNS depressants like benzodiazepines or barbiturates




Which drug has a low therepeutic index and potential for lethality?


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barbiturates




If you're given a 100mg of acetaminophen, how much will remain after one half-life?
And after two half-lives?

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After 1 half-life, 50mg would remain in the body and after two half-lives,
25mg would remain.




What is the limbic system?


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a region of the brain that integrates memory, emotion, and reward.
Together with the hypothalamus, the limbic system controls emotion and
behaviour




What is the duration of action of barbiturates?


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-Long acting (1-2days)
-Short Acting (3-8hours)
-Ultra Short Acting (20 minutes)




What is the only therapeutic use of cocaine?


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as a local aesthetic for the mouth and throat; however rarely used

,What is the mechanism of action of nicotine?


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activates nicotinic receptors that increase psychomotor activity, cognitive
function, attention, and memory.




What does a therapeutic index of 2 tell you about the drug toxicity?


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Since there is only a 2-fold difference between the beneficial dose and the
toxic dose, it's more probable that adverse effects will occur




Thiopental


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An ultra-short acting sedative that functions rapidly induce anaesthesia.




What are some reasons for variations in drug response between two people?


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, genetic factors, environmental factors, disease states, altered physiological
stages, presence of other drugs




what are the common reason athletes use blood doping?


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increase speed and endurance




Name 2 commonly used stimulant drugs


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Nicotine and Caffeine




How is caffeine eliminated?


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half-life of caffeine varies from individuals between 2.5 - 10 hours and
excreted from kidneys




How do you calculate the therapeutic index?


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