PTCB Immunization Exam Questions and
Answers
1. 1. Which of the following antibody classes is the mediator of
allergy and anaphylaxis?
a. IgA
b. IgE
c. IgG
d. IgM
ANS B
2. 1. Which of the following describes the role of Helper T cells in
mounting an immune response to a vaccine?
a. Directly kills infected cells
b. Present antigen to antibodies
c. Produce cytokines that stimulate B cells to produce antibodies
d. Produce large amounts of antigen specific antibodies
ANS C
3. 1. Which of the following is an advantage of passive immunity
compared to active immunity?
a. Passive immunity develops in response to infection or after giving a
vaccine or toxoid
,b. Passive immunity is long-lasting
c.Passive immunity doesn't interfere with the development immune
responses from live vaccines
d. Passive immunity protects almost immediately
ANS D
4. 1. Which of the following is NOT an example of active immunity?
a. Administration of a recombinant immunogenic protein
b. Infection with natural disease
c. Administration of high titer immune globulin
d. Administration of a live attenuated viral vaccine
ANS C
5. 1. Mary received a blood transfusion following a recent motor
vehicle acci- dent. Response to which of the following vaccines will
be most affected by this event?
a. Pneumococcal polysaccharide vaccine (PPSV)
b. Tetanus-diphtheria
c. Measles vaccine
d. Inactivated influence vaccine (IIV)
ANS C
6. 1. A US born 67-year-old was recently diagnosed with diabetes.
His vaccine records indicate that he received his Tdap,
,pneumococcal (PPSV23), and in- fluenza vaccines in October 2015.
What vaccines would you recommend for him?
a. Influenza vaccine, PCV13, varicella vaccine, and hepatitis B vaccine
series
b. Influenza vaccine, zoster, PCV13, and hepatitis B vaccine series
c. Influenza vaccine and hepatitis B vaccine series
d. Influenza vaccine, zoster vaccine, and hepatitis B vaccine series
ANS B
7. 1. Which of the following is/are true regarding live attenuated
vaccines?
a. The injectable live attenuated vaccines usually product immunity
with one dose
b. They are stronger versions of the "wild" virus
c. Live attenuated vaccines generally have milder reactions versus
inactivated vaccines
d. All of the above
ANS A
8. 1. Joe is a 28-year-old accountant who traveled to Bangkok for a
two-month visit two years ago. As part of his preparations for that
trip he received a dose of hepatitis A vaccine. He has received only
a Tdap booster for a finger laceration since his return. He is not
planning a trip to Beijing and seeks your advice regarding hepatitis
, A vaccination. What do you recommend?
a. He should start the hepatitis A series over and receive a dose
now and another dose in 6 months
b. He should receive a dose of hepatitis A vaccine now to complete the
series
c. He should receive a double dose of hepatitis A vaccine prior to his
departure
d. He should receive a half dose of hepatitis A vaccine now and
another dose in 6 months
ANS B
9. 1. Which of the following represents a true contraindication to
measles vac- cine?
a. History of thrombocytopenia
b. Vaccine candidate's mother is pregnant
c. Vaccine candidate is pregnant
d. Moderate or severe acute illness with or without fever
ANS C
10. 1. A 26-year-old female received the second dose in her
series of varicella vaccine 2 weeks ago. Today she stepped on a
rusty nail while working on
her farm. Her last tetanus-diphtheria (Td) dose was 6 years ago.
Which of the following immunization strategies is appropriate?
Answers
1. 1. Which of the following antibody classes is the mediator of
allergy and anaphylaxis?
a. IgA
b. IgE
c. IgG
d. IgM
ANS B
2. 1. Which of the following describes the role of Helper T cells in
mounting an immune response to a vaccine?
a. Directly kills infected cells
b. Present antigen to antibodies
c. Produce cytokines that stimulate B cells to produce antibodies
d. Produce large amounts of antigen specific antibodies
ANS C
3. 1. Which of the following is an advantage of passive immunity
compared to active immunity?
a. Passive immunity develops in response to infection or after giving a
vaccine or toxoid
,b. Passive immunity is long-lasting
c.Passive immunity doesn't interfere with the development immune
responses from live vaccines
d. Passive immunity protects almost immediately
ANS D
4. 1. Which of the following is NOT an example of active immunity?
a. Administration of a recombinant immunogenic protein
b. Infection with natural disease
c. Administration of high titer immune globulin
d. Administration of a live attenuated viral vaccine
ANS C
5. 1. Mary received a blood transfusion following a recent motor
vehicle acci- dent. Response to which of the following vaccines will
be most affected by this event?
a. Pneumococcal polysaccharide vaccine (PPSV)
b. Tetanus-diphtheria
c. Measles vaccine
d. Inactivated influence vaccine (IIV)
ANS C
6. 1. A US born 67-year-old was recently diagnosed with diabetes.
His vaccine records indicate that he received his Tdap,
,pneumococcal (PPSV23), and in- fluenza vaccines in October 2015.
What vaccines would you recommend for him?
a. Influenza vaccine, PCV13, varicella vaccine, and hepatitis B vaccine
series
b. Influenza vaccine, zoster, PCV13, and hepatitis B vaccine series
c. Influenza vaccine and hepatitis B vaccine series
d. Influenza vaccine, zoster vaccine, and hepatitis B vaccine series
ANS B
7. 1. Which of the following is/are true regarding live attenuated
vaccines?
a. The injectable live attenuated vaccines usually product immunity
with one dose
b. They are stronger versions of the "wild" virus
c. Live attenuated vaccines generally have milder reactions versus
inactivated vaccines
d. All of the above
ANS A
8. 1. Joe is a 28-year-old accountant who traveled to Bangkok for a
two-month visit two years ago. As part of his preparations for that
trip he received a dose of hepatitis A vaccine. He has received only
a Tdap booster for a finger laceration since his return. He is not
planning a trip to Beijing and seeks your advice regarding hepatitis
, A vaccination. What do you recommend?
a. He should start the hepatitis A series over and receive a dose
now and another dose in 6 months
b. He should receive a dose of hepatitis A vaccine now to complete the
series
c. He should receive a double dose of hepatitis A vaccine prior to his
departure
d. He should receive a half dose of hepatitis A vaccine now and
another dose in 6 months
ANS B
9. 1. Which of the following represents a true contraindication to
measles vac- cine?
a. History of thrombocytopenia
b. Vaccine candidate's mother is pregnant
c. Vaccine candidate is pregnant
d. Moderate or severe acute illness with or without fever
ANS C
10. 1. A 26-year-old female received the second dose in her
series of varicella vaccine 2 weeks ago. Today she stepped on a
rusty nail while working on
her farm. Her last tetanus-diphtheria (Td) dose was 6 years ago.
Which of the following immunization strategies is appropriate?
