SEPSIS QUESTIONS WITH DETAILED VERIFIED AND 100%
ACCURATE ANSWERS
What is the pathophysiology of sepsis? Correct Answers
What is the result of the release of pro-inflammatory mediators in
sepsis? Correct Answers Magnitude of the inflammatory response
exceeds localized area and produces systemic dysfunction (dysregulated
immune response)
increase WBC and Temp
Sepsis leads to what in the body? Correct Answers 1.) Endothelial
Dysfunction
2.) Cardiovascular Dysfunction
3.) Multi-Organ Failure
Describe the Endothelial Dysfunction associated with sepsis. Correct
Answers The endothelium participates in regulation of vascular tone,
cell and nutrient movement, and coagulation. Each of these becomes
disrupted, resulting in decreased vascular tone, increased permeability,
and a pro-coagulant state
Describe the Cardiovascular Dysfunction associated with sepsis. Correct
Answers The heart increases the rate and force of contraction resulting
in an increased cardiac output to attempt to maintain BP with the loss of
vascular tone. Increased need for oxygenation and ventilation due to
hyper-metabolic state
, What vital sign changes result from the Dysfunction associated with
sepsis? Correct Answers increase HR & RR
Describe the Multi-Organ Failure associated with sepsis. Correct
Answers Hypoperfusion and cellular damage from reactive oxygen
species and inflammatory mediators cause failure of vital processes
across multiple organ systems
What are the SIRS criteria? Correct Answers 1.) WBC >12 or <4 or
>10% bands
2.) T >38 or <36
3.) HR >90
4.) RR >20
What was the definition of Sepsis (2016)? Correct Answers ≥ 2/4 SIRS
Criteria
Suspected Infection
What was the definition of severe Sepsis (2016)? Correct Answers ≥ 2/4
SIRS Criteria or Suspected Infection + End Organ Dysfunction
What are some signs of End Organ Dysfunction? Correct Answers
ACCURATE ANSWERS
What is the pathophysiology of sepsis? Correct Answers
What is the result of the release of pro-inflammatory mediators in
sepsis? Correct Answers Magnitude of the inflammatory response
exceeds localized area and produces systemic dysfunction (dysregulated
immune response)
increase WBC and Temp
Sepsis leads to what in the body? Correct Answers 1.) Endothelial
Dysfunction
2.) Cardiovascular Dysfunction
3.) Multi-Organ Failure
Describe the Endothelial Dysfunction associated with sepsis. Correct
Answers The endothelium participates in regulation of vascular tone,
cell and nutrient movement, and coagulation. Each of these becomes
disrupted, resulting in decreased vascular tone, increased permeability,
and a pro-coagulant state
Describe the Cardiovascular Dysfunction associated with sepsis. Correct
Answers The heart increases the rate and force of contraction resulting
in an increased cardiac output to attempt to maintain BP with the loss of
vascular tone. Increased need for oxygenation and ventilation due to
hyper-metabolic state
, What vital sign changes result from the Dysfunction associated with
sepsis? Correct Answers increase HR & RR
Describe the Multi-Organ Failure associated with sepsis. Correct
Answers Hypoperfusion and cellular damage from reactive oxygen
species and inflammatory mediators cause failure of vital processes
across multiple organ systems
What are the SIRS criteria? Correct Answers 1.) WBC >12 or <4 or
>10% bands
2.) T >38 or <36
3.) HR >90
4.) RR >20
What was the definition of Sepsis (2016)? Correct Answers ≥ 2/4 SIRS
Criteria
Suspected Infection
What was the definition of severe Sepsis (2016)? Correct Answers ≥ 2/4
SIRS Criteria or Suspected Infection + End Organ Dysfunction
What are some signs of End Organ Dysfunction? Correct Answers
