lOMoARcPSD|50131128
ATI RN Pharmacology Practice Exam (2026)
, lOMoARcPSD|50131128
Section 60 total marks
Multiple Choice
Select the single best answer for each question.
Question 1 2 marks
A nurse is reviewing a medication order that is poorly handwritten and ambiguous. Which of the
following actions is the priority to ensure patient safety?
A Contact the prescribing healthcare provider for clarification of the order.
B Consult with a fellow nurse and proceed if both agree on the meaning.
C Administer the lowest possible dose of the medication to minimize risk.
D Ask the patient if they recall the correct dosage from previous use.
Question 2 2 marks
Which of the following pharmacological terms describes the study of how a drug is absorbed, distrib-
uted, metabolized, and excreted by the body?
A Pharmacokinetics
B Pharmacodynamics
C Pharmacogenetics
D Therapeutic Index
Question 3 2 marks
A nurse is teaching a client who has a new prescription for Albuterol. The nurse should explain that the
primary mechanism of action for this medication is to:
A Prevent the growth of fungal organisms in the mouth.
B Cause rapid bronchodilation by relaxing smooth muscle.
C Reduce the viscosity of thick respiratory secretions.
D Decrease inflammation in the airway over several weeks.
, lOMoARcPSD|50131128
Question 4 2 marks
When administering an intramuscular (IM) injection of an antibiotic known to be irritating to the tissues,
which technique is recommended to prevent leaking into the subcutaneous tissue?
A Utilize the Z-track method.
B Apply vigorous massage to the site after injection.
C Use a inch needle to ensure shallow delivery.
D Aspirate for 10 seconds before injecting.
Question 5 2 marks
A nurse discovers that a client was accidentally administered an expired medication. Which of the
following actions should the nurse perform first?
A Notify the pharmacy to replace the stock.
B Assess the client's condition and vital signs.
C Inform the nurse manager of the error.
D Complete an incident report per facility policy.
Question 6 2 marks
A provider orders g of a medication to be given orally. The medication is available in mg
tablets. How many tablets should the nurse administer?
A 0.5 tablets
B 4 tablets
C 1 tablet
D 2 tablets
ATI RN Pharmacology Practice Exam (2026)
, lOMoARcPSD|50131128
Section 60 total marks
Multiple Choice
Select the single best answer for each question.
Question 1 2 marks
A nurse is reviewing a medication order that is poorly handwritten and ambiguous. Which of the
following actions is the priority to ensure patient safety?
A Contact the prescribing healthcare provider for clarification of the order.
B Consult with a fellow nurse and proceed if both agree on the meaning.
C Administer the lowest possible dose of the medication to minimize risk.
D Ask the patient if they recall the correct dosage from previous use.
Question 2 2 marks
Which of the following pharmacological terms describes the study of how a drug is absorbed, distrib-
uted, metabolized, and excreted by the body?
A Pharmacokinetics
B Pharmacodynamics
C Pharmacogenetics
D Therapeutic Index
Question 3 2 marks
A nurse is teaching a client who has a new prescription for Albuterol. The nurse should explain that the
primary mechanism of action for this medication is to:
A Prevent the growth of fungal organisms in the mouth.
B Cause rapid bronchodilation by relaxing smooth muscle.
C Reduce the viscosity of thick respiratory secretions.
D Decrease inflammation in the airway over several weeks.
, lOMoARcPSD|50131128
Question 4 2 marks
When administering an intramuscular (IM) injection of an antibiotic known to be irritating to the tissues,
which technique is recommended to prevent leaking into the subcutaneous tissue?
A Utilize the Z-track method.
B Apply vigorous massage to the site after injection.
C Use a inch needle to ensure shallow delivery.
D Aspirate for 10 seconds before injecting.
Question 5 2 marks
A nurse discovers that a client was accidentally administered an expired medication. Which of the
following actions should the nurse perform first?
A Notify the pharmacy to replace the stock.
B Assess the client's condition and vital signs.
C Inform the nurse manager of the error.
D Complete an incident report per facility policy.
Question 6 2 marks
A provider orders g of a medication to be given orally. The medication is available in mg
tablets. How many tablets should the nurse administer?
A 0.5 tablets
B 4 tablets
C 1 tablet
D 2 tablets
