CITI
Training: Biomedical Research Modules 1–24 |
Practice Questions, Answers & Complete Solutions
Resource Features
➢ Biomedical Research practice questions
➢ Answers for self-assessment
➢ Detailed explanations and rationales
➢ Human-subjects protection review
➢ IRB practice scenarios
, CITI Training (Biomedical Research) Test Bank
Modules 1-24: Complete with Questions, Answers, and
Rationales
Question 1
The Belmont Report's principle of respect for persons incorporates at least
two ethical convictions: first, that individuals should be treated as
autonomous agents, and second, that:
A. Persons with diminished autonomy should only participate in no more
than minimal risk research.
B. Persons with diminished autonomy should be excluded from research.
C. Persons with diminished autonomy are entitled to protection.
D. Persons involved in research cannot financially benefit.
Answer: C. Persons with diminished autonomy are entitled to
protection.
Rationale: The Belmont Report's principle of respect for persons requires
that individuals be treated as autonomous agents and that persons with
diminished autonomy are entitled to protection. This recognizes that some
individuals may have diminished capacity to make decisions and therefore
require additional safeguards.
Question 2
,Which of the following is an example of how the principle of beneficence
can be applied to a study employing human subjects?
A. Ensuring that persons with diminished autonomy are protected.
B. Providing detailed information about the study and obtaining the
subject's consent to participate.
C. Determining that the study has a maximization of benefits and a
minimization of risks.
D. Ensuring that the selection of subjects includes people from all segments
of the population.
Answer: C. Determining that the study has a maximization of benefits
and a minimization of risks.
Rationale: The principle of beneficence requires researchers to maximize
possible benefits and minimize possible risks to subjects. This involves
careful consideration of the risk-benefit ratio in research design.
Question 3
Which of the following are the three principles discussed in the Belmont
Report?
A. IRB Review, Federal Regulations, Declaration of Helsinki
B. Privacy, Confidentiality, Equitable Selection of Subjects
C. Informed Consent, Institutional Assurance, Researcher Responsibility
D. Respect for Persons, Beneficence, Justice
Answer: D. Respect for Persons, Beneficence, Justice
, Rationale: The Belmont Report identifies three fundamental ethical
principles for research involving human subjects: Respect for Persons,
Beneficence, and Justice.
Question 4
When an IRB is reviewing a research study and they are considering if a
potential subject population is vulnerable, they should consider:
A. Are there adequate resources to conduct the study?
B. Is there a power differential between researchers and subjects?
C. Has the researcher completed required training?
D. Are the research procedures greater than minimal risk of harm?
Answer: B. Is there a power differential between researchers and
subjects?
Rationale: Vulnerability often arises from power differentials between
researchers and subjects. The IRB should consider whether the relationship
between researchers and potential subjects could compromise voluntary
participation or informed consent.
Question 5
Which is an example of a situation where deferential vulnerability might be
a factor?
A. An army medical officer recruiting subjects among lower ranks
B. A college professor recruiting among their students
Training: Biomedical Research Modules 1–24 |
Practice Questions, Answers & Complete Solutions
Resource Features
➢ Biomedical Research practice questions
➢ Answers for self-assessment
➢ Detailed explanations and rationales
➢ Human-subjects protection review
➢ IRB practice scenarios
, CITI Training (Biomedical Research) Test Bank
Modules 1-24: Complete with Questions, Answers, and
Rationales
Question 1
The Belmont Report's principle of respect for persons incorporates at least
two ethical convictions: first, that individuals should be treated as
autonomous agents, and second, that:
A. Persons with diminished autonomy should only participate in no more
than minimal risk research.
B. Persons with diminished autonomy should be excluded from research.
C. Persons with diminished autonomy are entitled to protection.
D. Persons involved in research cannot financially benefit.
Answer: C. Persons with diminished autonomy are entitled to
protection.
Rationale: The Belmont Report's principle of respect for persons requires
that individuals be treated as autonomous agents and that persons with
diminished autonomy are entitled to protection. This recognizes that some
individuals may have diminished capacity to make decisions and therefore
require additional safeguards.
Question 2
,Which of the following is an example of how the principle of beneficence
can be applied to a study employing human subjects?
A. Ensuring that persons with diminished autonomy are protected.
B. Providing detailed information about the study and obtaining the
subject's consent to participate.
C. Determining that the study has a maximization of benefits and a
minimization of risks.
D. Ensuring that the selection of subjects includes people from all segments
of the population.
Answer: C. Determining that the study has a maximization of benefits
and a minimization of risks.
Rationale: The principle of beneficence requires researchers to maximize
possible benefits and minimize possible risks to subjects. This involves
careful consideration of the risk-benefit ratio in research design.
Question 3
Which of the following are the three principles discussed in the Belmont
Report?
A. IRB Review, Federal Regulations, Declaration of Helsinki
B. Privacy, Confidentiality, Equitable Selection of Subjects
C. Informed Consent, Institutional Assurance, Researcher Responsibility
D. Respect for Persons, Beneficence, Justice
Answer: D. Respect for Persons, Beneficence, Justice
, Rationale: The Belmont Report identifies three fundamental ethical
principles for research involving human subjects: Respect for Persons,
Beneficence, and Justice.
Question 4
When an IRB is reviewing a research study and they are considering if a
potential subject population is vulnerable, they should consider:
A. Are there adequate resources to conduct the study?
B. Is there a power differential between researchers and subjects?
C. Has the researcher completed required training?
D. Are the research procedures greater than minimal risk of harm?
Answer: B. Is there a power differential between researchers and
subjects?
Rationale: Vulnerability often arises from power differentials between
researchers and subjects. The IRB should consider whether the relationship
between researchers and potential subjects could compromise voluntary
participation or informed consent.
Question 5
Which is an example of a situation where deferential vulnerability might be
a factor?
A. An army medical officer recruiting subjects among lower ranks
B. A college professor recruiting among their students
