And Answers 2026/2027 chamberlain
1. A master's-prepared nurse is analyzing research findings to determine if a
new intervention should be adopted in practice. The nurse notes that the
study results are statistically significant (p < 0.05) but is uncertain about
their practical importance. Which concept should the nurse evaluate to
determine the real-world impact of the findings?
A) Statistical power
B) Clinical significance
C) Internal validity
D) Reliability
**Correct Answer:** B) Clinical significance
**Rationale:** Clinical significance refers to the practical importance and
real-world impact of research findings, indicating whether the intervention
produces a meaningful difference in patient outcomes. Statistical significance
only indicates that results are unlikely due to chance, not that they are
clinically meaningful.
2. A nurse researcher is comparing two treatment groups and finds a
statistically significant difference with a p-value of 0.03. Which of the
following is the correct interpretation of this p-value?
A) There is a 3% probability that the null hypothesis is true
B) There is a 3% probability that the results are due to chance, assuming the
null hypothesis is true
C) The treatment effect is clinically significant
D) There is a 97% chance that the alternative hypothesis is true
**Correct Answer:** B) There is a 3% probability that the results are due to
chance, assuming the null hypothesis is true
, **Rationale:** A p-value represents the probability of obtaining results as
extreme as those observed, assuming the null hypothesis is true. A p-value
of 0.03 means there is a 3% chance of observing the results if no true
difference exists. It does not directly indicate the probability that the null
hypothesis is true or the clinical significance of the findings.
3. A nurse is leading a quality improvement initiative to reduce catheter-
associated urinary tract infections (CAUTIs). The team implements a new
evidence-based protocol and observes a 30% reduction in infection rates.
The nurse should consider this finding as:
A) Clinically significant because it represents a meaningful improvement in
patient outcomes
B) Statistically significant only
C) Not clinically relevant because it is not statistically significant
D) Only relevant if the p-value is less than 0.05
**Correct Answer:** A) Clinically significant because it represents a
meaningful improvement in patient outcomes
**Rationale:** Clinical significance is determined by the practical impact of
an intervention on patient outcomes. A 30% reduction in infection rates
represents a meaningful improvement in patient safety and quality of care,
regardless of statistical testing. Statistical significance and clinical
significance are distinct concepts that should both be considered.
4. According to the 2021 AACN Essentials, which domain focuses on the
master's-prepared nurse's ability to translate evidence into practice and
evaluate outcomes?
A) Domain 1: Knowledge for Nursing Practice
B) Domain 4: Scholarship for Nursing Practice
C) Domain 5: Quality and Safety