HESI A2 Entrance Exam Prep 2026–2027 | 318
Practice Questions with Answers & Detailed
Rationales | Math, Reading, Vocabulary, Grammar,
Biology, Chemistry, Anatomy & Physiology +
Comprehensive Mock Exam
HESI A2 ENTRANCE EXAM
Table of Contents
Updated 2026–2027
Section Content Area High-Yield Coverage
Whole numbers, fractions, decimals, percentages,
ratios, proportions, algebra, metric & household
I Mathematics
conversions, military time, dosage-style
calculations, tables and graphs
Main idea, supporting details, inference,
Reading summaries, author's purpose, tone, context clues,
II
Comprehension sequencing, fact vs. opinion, source evaluation,
data interpretation
General and healthcare vocabulary, medical
Vocabulary &
III terminology, prefixes, suffixes, roots, synonyms,
General Knowledge
antonyms, context clues and word usage
Sentence structure, subject–verb agreement,
pronouns, verb tense, modifiers, punctuation,
IV Grammar
possessives, capitalization, spelling and
commonly confused words
Cell structure, macromolecules, enzymes,
DNA/RNA, protein synthesis, genetics, mitosis,
V Biology
meiosis, cellular respiration, photosynthesis and
membrane transport
Atomic structure, periodic table, bonding,
chemical reactions, acids and bases, solutions,
VI Chemistry
states of matter, gas behavior, density, redox and
nuclear chemistry
Anatomy & Anatomical terminology, homeostasis, tissues,
VII
Physiology body systems, organ functions, hormones,
,Section Content Area High-Yield Coverage
circulation, respiration, digestion, urinary
function and system integration
Mixed high-difficulty questions integrating all
Comprehensive
seven core subject areas with calculations,
VIII HESI A2 Mock
passages, tables, diagrams and data-based
Exam
reasoning
Premium Exam Features
• Difficult, high-yield and commonly tested concepts
• Detailed answer rationales and exam strategies
• Tables, diagrams, sketches, graphs and data displays
• Clinical and real-world application questions
• Integrated multistep and critical-reasoning problems
• Section-by-section answer keys
• Updated 2026–2027 comprehensive preparation
HESI A2 ENTRANCE EXAM — SECTION I: MATHEMATICS
Question 1
A supply department begins with 5,460 examination gloves. During the
morning, 1,785 gloves are used. An afternoon delivery adds 2,240 gloves, after
which another 675 gloves are used. How many gloves remain?
A. 4,365 B. 4,565 C. 5,015 D. 5,240
Correct Answer: D — 5,240
Rationale:
[ 5460-1785+2240-675=5240 ]
🎯 HESI Strategy: Process multistep inventory problems in the exact
chronological order given.
💡 Math Pearl: Intermediate values are often included as distractors.
,Yes. I’ll make it high-yield and challenging, while keeping the same structure
as your sample. Questions will emphasize concepts students are likely to need
for HESI A2 preparation, with clear distractors and useful rationales.
HESI A2 ENTRANCE EXAM — SECTION I: MATHEMATICS
Question 2
A nursing student needs to convert 2.75 liters of IV fluid into milliliters. How
many milliliters are equivalent to 2.75 liters?
A. 27.5 mL
B. 275 mL
C. 2,750 mL
D. 27,500 mL
Correct Answer: C — 2,750 mL
Rationale:
There are 1,000 milliliters (mL) in 1 liter (L).
2.75 L×1,000 mL1 L=2,750 mL2.75\text{ L}\times\frac{1,000\text{
mL}}{1\text{ L}}=2,750\text{ mL}
Therefore, 2.75 L = 2,750 mL.
🎯 HESI Strategy: Memorize the most frequently tested metric conversions: 1
L = 1,000 mL, 1 g = 1,000 mg, and 1 kg = 1,000 g.
💡 Math Pearl: When converting a larger metric unit to a smaller unit, the
numerical value increases.
Question 3
A patient drinks 34\frac{3}{4} of a 240-mL bottle of water. How many
milliliters of water did the patient drink?
A. 160 mL
B. 180 mL
C. 200 mL
D. 210 mL
, Correct Answer: B — 180 mL
Rationale:
Multiply the total volume by the fraction consumed:
34×240\frac{3}{4}\times240
First divide:
240÷4=60240\div4=60
Then multiply:
60×3=18060\times3=180
Therefore, the patient drank 180 mL.
🎯 HESI Strategy: For fraction-of-a-number questions, divide by the
denominator first and multiply by the numerator.
💡 Math Pearl: Always identify whether the question asks for the amount
used, remaining, increased, or decreased.
Question 4
A clinic has 360 syringes. If 15% are defective, how many syringes are
defective?
A. 36
B. 45
C. 54
D. 60
Correct Answer: C — 54
Rationale:
Convert 15% to a decimal:
15%=0.1515\%=0.15
Then calculate:
Practice Questions with Answers & Detailed
Rationales | Math, Reading, Vocabulary, Grammar,
Biology, Chemistry, Anatomy & Physiology +
Comprehensive Mock Exam
HESI A2 ENTRANCE EXAM
Table of Contents
Updated 2026–2027
Section Content Area High-Yield Coverage
Whole numbers, fractions, decimals, percentages,
ratios, proportions, algebra, metric & household
I Mathematics
conversions, military time, dosage-style
calculations, tables and graphs
Main idea, supporting details, inference,
Reading summaries, author's purpose, tone, context clues,
II
Comprehension sequencing, fact vs. opinion, source evaluation,
data interpretation
General and healthcare vocabulary, medical
Vocabulary &
III terminology, prefixes, suffixes, roots, synonyms,
General Knowledge
antonyms, context clues and word usage
Sentence structure, subject–verb agreement,
pronouns, verb tense, modifiers, punctuation,
IV Grammar
possessives, capitalization, spelling and
commonly confused words
Cell structure, macromolecules, enzymes,
DNA/RNA, protein synthesis, genetics, mitosis,
V Biology
meiosis, cellular respiration, photosynthesis and
membrane transport
Atomic structure, periodic table, bonding,
chemical reactions, acids and bases, solutions,
VI Chemistry
states of matter, gas behavior, density, redox and
nuclear chemistry
Anatomy & Anatomical terminology, homeostasis, tissues,
VII
Physiology body systems, organ functions, hormones,
,Section Content Area High-Yield Coverage
circulation, respiration, digestion, urinary
function and system integration
Mixed high-difficulty questions integrating all
Comprehensive
seven core subject areas with calculations,
VIII HESI A2 Mock
passages, tables, diagrams and data-based
Exam
reasoning
Premium Exam Features
• Difficult, high-yield and commonly tested concepts
• Detailed answer rationales and exam strategies
• Tables, diagrams, sketches, graphs and data displays
• Clinical and real-world application questions
• Integrated multistep and critical-reasoning problems
• Section-by-section answer keys
• Updated 2026–2027 comprehensive preparation
HESI A2 ENTRANCE EXAM — SECTION I: MATHEMATICS
Question 1
A supply department begins with 5,460 examination gloves. During the
morning, 1,785 gloves are used. An afternoon delivery adds 2,240 gloves, after
which another 675 gloves are used. How many gloves remain?
A. 4,365 B. 4,565 C. 5,015 D. 5,240
Correct Answer: D — 5,240
Rationale:
[ 5460-1785+2240-675=5240 ]
🎯 HESI Strategy: Process multistep inventory problems in the exact
chronological order given.
💡 Math Pearl: Intermediate values are often included as distractors.
,Yes. I’ll make it high-yield and challenging, while keeping the same structure
as your sample. Questions will emphasize concepts students are likely to need
for HESI A2 preparation, with clear distractors and useful rationales.
HESI A2 ENTRANCE EXAM — SECTION I: MATHEMATICS
Question 2
A nursing student needs to convert 2.75 liters of IV fluid into milliliters. How
many milliliters are equivalent to 2.75 liters?
A. 27.5 mL
B. 275 mL
C. 2,750 mL
D. 27,500 mL
Correct Answer: C — 2,750 mL
Rationale:
There are 1,000 milliliters (mL) in 1 liter (L).
2.75 L×1,000 mL1 L=2,750 mL2.75\text{ L}\times\frac{1,000\text{
mL}}{1\text{ L}}=2,750\text{ mL}
Therefore, 2.75 L = 2,750 mL.
🎯 HESI Strategy: Memorize the most frequently tested metric conversions: 1
L = 1,000 mL, 1 g = 1,000 mg, and 1 kg = 1,000 g.
💡 Math Pearl: When converting a larger metric unit to a smaller unit, the
numerical value increases.
Question 3
A patient drinks 34\frac{3}{4} of a 240-mL bottle of water. How many
milliliters of water did the patient drink?
A. 160 mL
B. 180 mL
C. 200 mL
D. 210 mL
, Correct Answer: B — 180 mL
Rationale:
Multiply the total volume by the fraction consumed:
34×240\frac{3}{4}\times240
First divide:
240÷4=60240\div4=60
Then multiply:
60×3=18060\times3=180
Therefore, the patient drank 180 mL.
🎯 HESI Strategy: For fraction-of-a-number questions, divide by the
denominator first and multiply by the numerator.
💡 Math Pearl: Always identify whether the question asks for the amount
used, remaining, increased, or decreased.
Question 4
A clinic has 360 syringes. If 15% are defective, how many syringes are
defective?
A. 36
B. 45
C. 54
D. 60
Correct Answer: C — 54
Rationale:
Convert 15% to a decimal:
15%=0.1515\%=0.15
Then calculate:
