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UKMLA Blood & Lymph Practice Questions – Polycythaemia

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x50 Questions. Test your knowledge of polycythaemia with this UKMLA-style practice question set. Questions cover the distinction between primary and secondary erythrocytosis, including polycythaemia vera and hypoxia-driven causes. Practise interpreting haemoglobin, haematocrit, erythropoietin and JAK2 results while recognising important complications such as hyperviscosity and thrombosis. Ideal for high-yield UKMLA haematology revision.

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MLA SB A Qu estion B an k
Polycythaemia
50 single best answer questions — Domain 6: Conditions, Body system: Blood and Lymph




Based on the GMC Medical Licensing Assessment (MLA) content map — applicable from September 2026

,BLOOD AND LY MPH Question 1 of 50

Polycythaemia Polycythaemia vera: features




A 60-year-old man presents with facial plethora, headache, and pruritus that worsens after a hot bath. Full blood count shows a markedly
raised haematocrit. What is the most likely diagnosis?




A Iron deficiency anaemia


B Myelofibrosis


C Polycythaemia vera


D Secondary polycythaemia due to chronic hypoxia


E Relative (apparent) polycythaemia due to dehydration


Select the single best answer.

,BLOOD AND LY MPH Question 1 of 50 — Answer

Polycythaemia Polycythaemia vera: features




A 60-year-old man presents with facial plethora, headache, and pruritus that worsens after a hot bath. Full blood count shows a markedly raised haematocrit. What is the
most likely diagnosis?



A Iron deficiency anaemia


B Myelofibrosis


C Polycythaemia vera ✓ Correct



D Secondary polycythaemia due to chronic hypoxia


E Relative (apparent) polycythaemia due to dehydration



EXPLANATION

Polycythaemia vera classically presents with facial plethora, headache, and pruritus (characteristically worse after a hot bath, known as aquagenic pruritus), alongside
a markedly raised haematocrit.

, BLOOD AND LY MPH Question 2 of 50

Polycythaemia Polycythaemia vera: features




🖼
The image shown is from a 62-year-old man with polycythaemia vera. What does this photograph INSERT IMAGE
demonstrate, and what causes this finding? Clinical photograph showing facial plethora (ruddy, red-purple facial
complexion)




A An allergic reaction


B A normal, healthy complexion unrelated to his diagnosis


C Facial plethora


D Sunburn


E Rosacea unrelated to his polycythaemia vera


Select the single best answer.

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