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UKMLA Blood & Lymph Practice Questions – Disseminated Intravascular Coagulation (DIC)

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x50 Questions. Test your knowledge of disseminated intravascular coagulation with this focused UKMLA practice question set. Questions cover the causes, clinical features, investigation findings and management of DIC, including its association with sepsis, trauma, malignancy and obstetric emergencies. Practise recognising the characteristic combination of widespread coagulation activation, consumption of clotting factors and bleeding. Designed for high-yield UKMLA haematology and acute medicine revision.

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MLA SB A Qu estion B an k
Disseminated Intravascular Coagulation (DIC)
50 single best answer questions — Domain 6: Conditions, Body system: Blood and Lymph




Based on the GMC Medical Licensing Assessment (MLA) content map — applicable from September 2026

,BLOOD AND LY MPH Question 1 of 50

Disseminated Intravascular Coagulation Disseminated intravascular coagulation




What is the underlying pathophysiological process in disseminated intravascular coagulation (DIC)?




A Isolated platelet destruction only


B A purely fibrinolytic process with no clot formation


Widespread activation of the coagulation cascade, leading to consumption of clotting factors and platelets, causing simultaneous thrombosis
C
and bleeding


D An isolated inherited clotting factor deficiency


E Isolated deficiency of vitamin K-dependent factors


Select the single best answer.

,BLOOD AND LY MPH Question 1 of 50 — Answer

Disseminated Intravascular Coagulation Disseminated intravascular coagulation




What is the underlying pathophysiological process in disseminated intravascular coagulation (DIC)?




A Isolated platelet destruction only


B A purely fibrinolytic process with no clot formation


Widespread activation of the coagulation cascade, leading to consumption of clotting factors and platelets, causing simultaneous thrombosis and
C ✓ Correct
bleeding


D An isolated inherited clotting factor deficiency


E Isolated deficiency of vitamin K-dependent factors



EXPLANATION

DIC involves widespread, inappropriate activation of the coagulation cascade, consuming clotting factors and platelets, which paradoxically causes both microvascular
thrombosis and a bleeding tendency.

, BLOOD AND LY MPH Question 2 of 50

Disseminated Intravascular Coagulation Disseminated intravascular coagulation




Which of the following is a recognised trigger of disseminated intravascular coagulation?




A Well-controlled type 2 diabetes


B Mild dehydration


C Simple viral upper respiratory tract infection


D Severe sepsis


E Chronic stable angina


Select the single best answer.

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