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UKMLA Blood & Lymph Practice Questions – Anaemia

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x50 Questions. Test your knowledge of anaemia with this comprehensive set of UKMLA-style practice questions. The questions cover the major causes and patterns of anaemia, including microcytic, normocytic and macrocytic anaemia, iron deficiency, vitamin B12 and folate deficiency, haemolysis and anaemia of chronic disease. Designed to reinforce interpretation of clinical presentations and investigations while helping you recognise the most appropriate diagnosis, investigation and management. Ideal for high-yield UKMLA haematology revision.

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MLA SBA Question Bank
Anaemia
50 single best answer questions — Domain 6: Conditions, Body system: Blood and Lymph




Based on the GMC Medical Licensing Assessment (MLA) content map — applicable from September 2026

,BLOOD AND LYMPH Question 1 of 50

Anaemia Chronic kidney disease: anaemia




A 58-year-old man with stage 4 chronic kidney disease is found to have a normocytic anaemia. What is the most likely underlying cause?




A Vitamin B12 deficiency


B Bone marrow infiltration


C Haemolysis


D Reduced erythropoietin production by the kidneys


E Acute blood loss


Select the single best answer.

,BLOOD AND LYMPH Question 1 of 50 — Answer

Anaemia Chronic kidney disease: anaemia




A 58-year-old man with stage 4 chronic kidney disease is found to have a normocytic anaemia. What is the most likely underlying cause?




A Vitamin B12 deficiency


B Bone marrow infiltration


C Haemolysis


D Reduced erythropoietin production by the kidneys ✓ Correct



E Acute blood loss



EXPLANATION

Anaemia in CKD is primarily due to reduced renal erythropoietin production, leading to decreased red cell production; it is typically normocytic and normochromic.

, BLOOD AND LYMPH Question 2 of 50

Anaemia Pregnancy: anaemia




A pregnant woman at 28 weeks gestation has a haemoglobin of 105 g/L on routine screening, with a low MCV. What is the most likely
underlying cause?




A Aplastic anaemia


B Myelofibrosis


C Iron deficiency anaemia, exacerbated by increased iron demands and plasma volume expansion in pregnancy


D Sickle cell disease


E Polycythaemia vera


Select the single best answer.

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