SARAH MICHELLE LIVE REVIEW
PRACTICE QUESTIONS FOR NURSE
PRACTITIONER EXAM PREP
1. A 65-year-old male with NYHA Class III heart failure and type 2 diabetes presents for a
follow-up. Which of the following medications is contraindicated due to its potential to cause
fluid retention?
A. Lisinopril
B. Metformin
C. Pioglitazone
D. Amlodipine
Answer: C
Conceptual Explanation: Thiazolidinediones (TZDs) like pioglitazone cause sodium and
water retention and are contraindicated in patients with symptomatic heart failure.
2. A patient presents with a ‘herald patch’ followed by a ‘Christmas tree’ distribution of
smaller maculopapular lesions on the trunk. What is the most likely diagnosis?
A. Tinea Corporis
,B. Psoriasis
C. Pityriasis Rosea
D. Secondary Syphilis
Answer: C
Conceptual Explanation: Pityriasis Rosea typically begins with a single herald patch
followed by smaller lesions in a Christmas tree pattern along skin cleavage lines.
3. Which of the following physical exam findings is most suggestive of acute cholecystitis?
A. Murphy’s Sign
B. McBurney’s Sign
C. Rovsing’s Sign
D. Psoas Sign
Answer: A
Conceptual Explanation: Murphy’s sign, which is inspiratory arrest during deep palpation
of the right upper quadrant, is highly specific for acute cholecystitis.
4. A 24-year-old female presents with purulent vaginal discharge and cervical motion
tenderness. Which treatment regimen is currently recommended by the CDC for suspected
PID?
A. Ceftriaxone 250mg IM once + Azithromycin 1g PO once
B. Azithromycin 1g PO once
, C. Doxycycline 100mg BID x 7 days
D. Ceftriaxone 500mg IM once + Doxycycline 100mg BID x 14 days + Metronidazole 500mg
BID x 14 days
Answer: D
Conceptual Explanation: The CDC updated PID guidelines recommend Ceftriaxone 500mg
IM, Doxycycline, and Metronidazole for anaerobic coverage.
5. Which lab result is most characteristic of iron deficiency anemia?
A. High Ferritin, Low TIBC
B. Normal RDW, Low Hgb
C. High MCV, Low Reticulocytes
D. Low Ferritin, High TIBC
Answer: D
Conceptual Explanation: In iron deficiency, ferritin (storage iron) is low, and TIBC
(binding capacity) increases as the body attempts to find more iron.
6. A patient with a history of COPD presents with increased sputum purulence and dyspnea.
Which antibiotic is first-line for a COPD exacerbation in a patient with no risk factors for
Pseudomonas?
A. Amoxicillin-Clavulanate
B. Ciprofloxacin
PRACTICE QUESTIONS FOR NURSE
PRACTITIONER EXAM PREP
1. A 65-year-old male with NYHA Class III heart failure and type 2 diabetes presents for a
follow-up. Which of the following medications is contraindicated due to its potential to cause
fluid retention?
A. Lisinopril
B. Metformin
C. Pioglitazone
D. Amlodipine
Answer: C
Conceptual Explanation: Thiazolidinediones (TZDs) like pioglitazone cause sodium and
water retention and are contraindicated in patients with symptomatic heart failure.
2. A patient presents with a ‘herald patch’ followed by a ‘Christmas tree’ distribution of
smaller maculopapular lesions on the trunk. What is the most likely diagnosis?
A. Tinea Corporis
,B. Psoriasis
C. Pityriasis Rosea
D. Secondary Syphilis
Answer: C
Conceptual Explanation: Pityriasis Rosea typically begins with a single herald patch
followed by smaller lesions in a Christmas tree pattern along skin cleavage lines.
3. Which of the following physical exam findings is most suggestive of acute cholecystitis?
A. Murphy’s Sign
B. McBurney’s Sign
C. Rovsing’s Sign
D. Psoas Sign
Answer: A
Conceptual Explanation: Murphy’s sign, which is inspiratory arrest during deep palpation
of the right upper quadrant, is highly specific for acute cholecystitis.
4. A 24-year-old female presents with purulent vaginal discharge and cervical motion
tenderness. Which treatment regimen is currently recommended by the CDC for suspected
PID?
A. Ceftriaxone 250mg IM once + Azithromycin 1g PO once
B. Azithromycin 1g PO once
, C. Doxycycline 100mg BID x 7 days
D. Ceftriaxone 500mg IM once + Doxycycline 100mg BID x 14 days + Metronidazole 500mg
BID x 14 days
Answer: D
Conceptual Explanation: The CDC updated PID guidelines recommend Ceftriaxone 500mg
IM, Doxycycline, and Metronidazole for anaerobic coverage.
5. Which lab result is most characteristic of iron deficiency anemia?
A. High Ferritin, Low TIBC
B. Normal RDW, Low Hgb
C. High MCV, Low Reticulocytes
D. Low Ferritin, High TIBC
Answer: D
Conceptual Explanation: In iron deficiency, ferritin (storage iron) is low, and TIBC
(binding capacity) increases as the body attempts to find more iron.
6. A patient with a history of COPD presents with increased sputum purulence and dyspnea.
Which antibiotic is first-line for a COPD exacerbation in a patient with no risk factors for
Pseudomonas?
A. Amoxicillin-Clavulanate
B. Ciprofloxacin
